Patents by Inventor Antonino Amato

Antonino Amato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250046369
    Abstract: Systems, methods, and apparatuses are provided for drift compensation for codewords in memory. A memory device comprises memory cells and circuitry configured to sense a codeword stored in the array of memory cells using a reference voltage and determine an amount by which to adjust the reference voltage used to sense the codeword based on an estimated weight of the original codeword, a mean of threshold voltage values of each memory cell of the sensed codeword, and a total quantity of memory cells of the sensed codeword. The circuitry can further be configured to adjust the reference voltage used to sense the codeword by the determined amount.
    Type: Application
    Filed: October 23, 2024
    Publication date: February 6, 2025
    Inventors: Marco Sforzin, Paolo Amato, Luca Barletta, Marco Pietro Ferrari, Antonino Favano
  • Publication number: 20230414861
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: August 14, 2023
    Publication date: December 28, 2023
    Applicant: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20230355223
    Abstract: The present disclosure relates generally to methods and apparatus to control delivery of a sealant during an invasive procedure. Disclosed methods and apparatus control movement of a syringe to control injection of sealant stored therein. For example, disclosed methods and apparatus can displace the syringe body relative to the plunger as the syringe is withdrawn from the target site, rather than displacing the plunger relative to the syringe body, to thereby pressurize the sealant or inject the sealant in an amount proportional to a distance the syringe body is withdrawn. This reduces the variability in the amount of sealant delivered along the syringe withdrawal pathway. The disclosed methods and apparatus can increase precision in movement of a syringe, thereby increasing precision in sealant delivery.
    Type: Application
    Filed: May 20, 2021
    Publication date: November 9, 2023
    Inventors: J. Christopher Flaherty, Antonino Amato, Jason Schense, Massimo Romanelli, Maria L. Constantino, Francesco de Gaetano, Kasra Osouli
  • Patent number: 11724023
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: August 15, 2023
    Assignee: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20230079546
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: August 31, 2022
    Publication date: March 16, 2023
    Applicant: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20220387733
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: October 31, 2020
    Publication date: December 8, 2022
    Inventors: Marco D'Arienzo, Giovanni Ganelli, Antonino Amato
  • Patent number: 11464897
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: October 11, 2022
    Assignee: BETAGLUE TECHNOLOGIES S.P.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20220096734
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: October 11, 2021
    Publication date: March 31, 2022
    Applicant: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Patent number: 11141526
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: October 12, 2021
    Assignee: BetaGlue Technologies S.p.A
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20210128819
    Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
    Type: Application
    Filed: May 11, 2020
    Publication date: May 6, 2021
    Inventors: Antonino Amato, Giovanni Paganelli
  • Publication number: 20200147413
    Abstract: A method for measuring radiotherapy doses on a subject undergoing radiotherapy or other treatments with ionizing radiations includes: electrically insulating the subject during the radiotherapy treatment; applying at least one electrode to the subject, or connected to an amplifier with a system for acquiring the signal outgoing from the amplifier; detecting, by means of the at least one electrode, the voltage pulse produced during the radiotherapy treatment and deriving from the ionization secondary electrons set into motion and/or by the loaded net charge induced in the subject; converting said voltage pulse into a value of charge induced by the treatment in the subject; and determining the dose of ionizing radiations received by the subject by a processing system which uses the above value of the induced charge, the energy spectrum of the incident beam and the contact surface of the incident beam on the subject.
    Type: Application
    Filed: July 30, 2018
    Publication date: May 14, 2020
    Applicant: Istituto Nazionale di Fisica Nucleare (INFN)
    Inventors: Giuseppe Antonio Pablo CIRRONE, Francesco ROMANO, Giada PETRINGA, Antonino AMATO
  • Patent number: 8952059
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: February 10, 2015
    Assignee: Sigma-Tau Industrie Faramceutiche Riunite S.p.A.
    Inventors: Antonino Amato, Menotti Calvani
  • Publication number: 20140024712
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Antonino AMATO, Menotti CALVANI
  • Patent number: 8569366
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: October 29, 2013
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Antonino Amato, Menotti Calvani
  • Patent number: 7560485
    Abstract: The present invention discloses a method for treating a subject suffering from intermittent claudication (IC) wherein said subject takes an effective dose of propionyl L-carnitine or a pharmaceutically acceptable salt thereof and also engaging in a concomitant physical training program. The method is particular effective for patients with intermittent claudication at class II of the Leriche-Fontaine's classification. The method provides a relief from peripheral arterial disease symptoms, as shown by claudication-limited exercise tolerance, while also improving quality of life.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: July 14, 2009
    Assignee: SIGMA-TAU Industrie Parmaceutiche Riunite S.p.A.
    Inventor: Antonino Amato
  • Publication number: 20080161604
    Abstract: The use of acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is described for the preparation of a medicament useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which said symptoms are selected from the group consisting of pain, paraesthesia and hyperaesthesia, in which the acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Application
    Filed: April 18, 2006
    Publication date: July 3, 2008
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
    Inventors: Menotti Calvani, Antonino Amato
  • Publication number: 20070213408
    Abstract: The use of acetyl L-carnitine, or one of its pharmaceutically acceptable salts, is described for the treatment of neu-ropathic pain in patients with type 2 diabetes not treated with insulin.
    Type: Application
    Filed: April 5, 2005
    Publication date: September 13, 2007
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Menotti Calvani, Antonino Amato
  • Publication number: 20060241058
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Application
    Filed: April 26, 2005
    Publication date: October 26, 2006
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Antonino Amato, Menotti Calvani
  • Publication number: 20060004095
    Abstract: Acetyl L-carnitine is used to treat neuropathic pain in patients with type 2 diabetes who are not treated with insulin.
    Type: Application
    Filed: October 21, 2004
    Publication date: January 5, 2006
    Inventors: Menotti Calvani, Antonino Amato