Patents by Inventor Antonio Bedalov

Antonio Bedalov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inhibiting deacetylase activity
    Patent number: 7514406
    Abstract: A method for identifying a compound that inhibits the NAD+-dependent deacetylase activity of a SIR2 protein is disclosed. These compounds are useful for the treatment of cancers and other diseases, through the activation of silenced genes, through the promotion of apoptosis in cancerous cells, and through the inhibition of transcriptional repressor activity in oncogenes.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: April 7, 2009
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Antonio Bedalov, Daniel E. Gottschling, Julian Simon
  • Interfering with telomere maintenance in treatment of diseases
    Publication number: 20050059077
    Abstract: The invention relates to novel nucleotide sequences and the polypeptide sequences derived therefrom, which are involved in yeast and mammalian telomere regulation. Methods for screening drugs and compositions are also provided. The invention furthermore relates to methods involving a diagnostic and/or therapeutic use of these gene(s)/protein(s), principally for treating cancer and aging.
    Type: Application
    Filed: October 27, 2004
    Publication date: March 17, 2005
    Applicant: Fred Hutchinson Cancer Research Center
    Inventors: Stephen Friend, Patrick Paddison, Melisa Dashiel, Antonio Bedalov