Patents by Inventor Antonio Chiocca

Antonio Chiocca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oncolytic virus
    Patent number: 8450106
    Abstract: Malignant tumors that are intrinsically resistant to conventional therapies are significant therapeutic challenges. An embodiment of the present invention provides an oncolytic virus capable of killing target cells, such as a tumor cells. In various embodiments presented herein, the oncolytic virus is armed or encodes a therapeutic polypeptide. In at least one embodiment, a recombinant oncolytic virus has been generated that can specifically replicate in cancer cells leading to their destruction and at the same time secrete robust amounts of a therapeutic polypeptide. Compositions and methods disclosed herein have broad therapeutic applicability.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: May 28, 2013
    Assignee: The Ohio State University Research Foundation
    Inventors: Balveen Kaur, Antonio Chiocca, Yoshinaga Saeki
  • ONCOLYTIC VIRUS
    Publication number: 20100272686
    Abstract: Malignant tumors that are intrinsically resistant to conventional therapies are significant therapeutic challenges. An embodiment of the present invention provides an oncolytic virus capable of killing target cells, such as a tumor cells. In various embodiments presented herein, the oncolytic virus is armed or encodes a therapeutic polypeptide. In at least one embodiment, a recombinant oncolytic virus has been generated that can specifically replicate in cancer cells leading to their destruction and at the same time secrete robust amounts of a therapeutic polypeptide. Compositions and methods disclosed herein have broad therapeutic applicability.
    Type: Application
    Filed: February 1, 2010
    Publication date: October 28, 2010
    Applicant: The Ohio State University Research Founddation
    Inventors: Balveen Kaur, Antonio Chiocca, Yoshinaga Saeki