Abstract: An example device for selection of one or more masses among a plurality of masses arranged and removably fixed to a guide of a main frame of a test machine for determining material properties of a material during a test, the selected mass or masses allowing to push an effector for performing the test, the device comprising: a means for selecting at least one mass among said plurality of masses, comprising a means to determine which mass or masses are selected, said means to determine being configured to send a signal indicative of which mass or masses are selected to a computing unit for controlling a test process using the selected mass or masses.

Abstract: The present disclosure provides therapeutic nanoparticles that include a first layer surrounding a core region, one or more particle modifiers present in or on the first layer, and one or more therapeutics present in the core region. Compositions and methods related to the nanoparticles are also provided.

Abstract: An example device for selection of one or more masses among a plurality of masses arranged and removably fixed to a guide of a main frame of a test machine for determining material properties of a material during a test, the selected mass or masses allowing to push an effector for performing the test, the device comprising: a means for selecting at least one mass among said plurality of masses, comprising a means to determine which mass or masses are selected, said means to determine being configured to send a signal indicative of which mass or masses are selected to a computing unit for controlling a test process using the selected mass or masses.

Abstract: An analyte monitoring platform consisting of a proximity communicator and an implantable biosensor that includes system architecture for biosensor authentication, identification and methods to use analyte sensors for general wellness. The system architecture also permits multi-analyte sensing. In addition, the system and methods can be used for a single analyte or combination of analytes.

Abstract: The present disclosure provides systems and methods for the continuous production of liposomes. An example method includes (a) mixing a solution of lipid and organic solvent from one or more containers to create an organic solvent-lipid solution, (b) providing the organic solvent-lipid solution to a first inlet of an injection port at a first flow rate, wherein the first inlet is in fluid communication with a first conduit, (c) providing an aqueous solution to a second inlet of the injection port at a second flow rate, wherein the second inlet is influid communication with a second conduit, wherein the first conduit is positioned concentrically within the second conduit at an outlet of the injection port, and wherein the first conduit extends through the outlet of the injection port, and (d) mixing the organic lipid solution and the aqueous solution to create a plurality of liposomes.

Abstract: The present disclosure provides systems and methods for the continuous production of liposomes. An example method includes (a) mixing a solution of lipid and organic solvent from one or more containers to create an organic solvent-lipid solution, (b) providing the organic solvent-lipid solution to a first inlet of an injection port at a first flow rate, wherein the first inlet is in fluid communication with a first conduit, (c) providing an aqueous solution to a second inlet of the injection port at a second flow rate, wherein the second inlet is in fluid communication with a second conduit, wherein the first conduit is positioned concentrically within the second conduit at an outlet of the injection port, and wherein the first conduit extends through the outlet of the injection port, and (d) mixing the organic lipid solution and the aqueous solution to create a plurality of liposomes.

Abstract: An analyte monitoring platform consisting of a proximity communicator and an implantable biosensor that includes system architecture for biosensor authentication, identification and methods to use analyte sensors for general wellness. The system architecture also permits multi-analyte sensing. In addition, the system and methods can be used for a single analyte or combination of analytes.

Abstract: A system and method is outlined for a wearable external device that communicates with a fully implantable miniaturized biosensor platform providing fast spatial detection and accurate assessment of the position and orientation of the implant within highly scattering tissue. The device and method provides spatial (x, y) position, depth (z) and rotational (?) state of the implantable biosensor platform. The spatial (x, y) position allows the ability to turn-on only one out of an entire array of LEDs that is in line-of-sight with the implant in order to conserve power. Similarly, the depth and rotational coordinates information is used to adjust the output light intensity of the selected light emitters to compensate the power delivered to the implant. The above attributes render the system compatible for usage during intense physical activity and for added user comfort through improved skin ventilation.

Abstract: A handle assembly is used with a pick-up truck tailgate. The handle assembly comprises a guide tube with an open end, a handle that is housed within the guide tube and a pivot assembly. The pivot assembly comprises a pivot pin connected to one end of the handle and a locking pin. The handle is moveable within the guide tube between a retracted position and an extended position. While in the extended position the handle passes through the open end and the handle may pivot about the pivot pin to move to a support position. When the handle is in the support position, the locking pin can engage the handle and releasably lock the handle in the support position. The guide tube is configured to be secured within a tailgate of a pick-up truck.

Abstract: A device and method are outlined for the manual or automated insertion and extraction of a miniaturized implantable biosensor underneath the skin. System comprises injection and extraction module that is in operable communication with a positioning and tracking module, microprocessor and data acquisition units. The positioning and tracking module utilizes light- or magnetic field-sensing arrays to provide spatial (x, y) position, depth (z) and rotational (?) state of the miniaturized implant. This is fed to the injection and extraction module that lines up a catheter. For extraction, the catheter is actively guided using sensing arrays to extract the biosensor. This system has also provisions to excise fibrosis tissue around the implant. This tool is operated in a manual or automatic mode to facilitate pain-free injection and extraction of a miniaturized biosensor with minimal trauma.

Abstract: A handle assembly is used with a pick-up truck tailgate. The handle assembly comprises a guide tube with an open end, a handle that is housed within the guide tube and a pivot assembly. The pivot assembly comprises a pivot pin connected to one end of the handle and a locking pin. The handle is moveable within the guide tube between a retracted position and an extended position. While in the extended position the handle passes through the open end and the handle may pivot about the pivot pin to move to a support position. When the handle is in the support position, the locking pin can engage the handle and releasably lock the handle in the support position. The guide tube is configured to be secured within a tailgate of a pick-up truck.

Abstract: There is disclosed a fastener for clips to be applied to jewelry and costume jewelry products and to clothing accessories, bags and the like. The fastener utilizes a mechanical device actuated through the action of magnets. According to one arrangement, the mobile components of the clip, shaped substantially in the form of small pins that carry out the mechanical fastening, consist of magnets, for which, in each pair of said permanent magnets, there is mutual attraction and therefore closing of the fastening device when they are arranged with the poles opposite, i.e. when one is arranged in such a way that its positive pole faces towards the negative pole of the other.

Abstract: There is disclosed a fastener for clips to be applied to jewelry and costume jewelry products and to clothing accessories, bags and the like. The fastener utilizes a mechanical device actuated through the action of magnets. According to one arrangement, the mobile components of the clip, shaped substantially in the form of small pins that carry out the mechanical fastening, consist of magnets, for which, in each pair of said permanent magnets, there is mutual attraction and therefore closing of the fastening device when they are arranged with the poles opposite, i.e. when one is arranged in such a way that its positive pole faces towards the negative pole of the other.

Abstract: A process for preparing a dermatological lotion comprises sequentially adding 160 to 240 g. salicylic acid, 160 to 240 g. alum powder and 45 to 55 tincture of iodine to 800 to 1200 ml. ethyl alcohol to provide a mixture, homogenizing the mixture, and then maintaining the homogenized mixture quiescent for at least one week.