Abstract: A system comprising: a container or box (1) provided with means for accessing the inside and means for opening and closing (3) the container or box (1) a smartphone (12) that may send and receive information to and from the container or box (1). Where the opening and closing means (3) are based on the use of biometric sensors for reading fingerprints and the smartphone enables the registering and de-registering of users to be controlled and remote opening and closing to be carried out. Furthermore, it comprises an electromechanical lock (4), electronic control (5) for opening and closing, signalling means of the operations carried out, which may be lights (7) or acoustic means such as a buzzer (8) and an opening and closing detection sensor (9). The secure transport and housing of products, and access by several users without needing to use keys or similar, with the possibility of configuring the activation or de-activation of the electronic register of opening and alarm events, is achieved.

Abstract: The present invention relates to novel compounds of the formula Ia: in any of its stereoisomeric forms or a mixture of stereoisomeric forms in any ratio, or a physiologically acceptable salt thereof, wherein the substituents are as described herein. The inventive compounds have CXCR5 inhibitory activity, and are particularly useful in treating or preventing various inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn's Disease, associated with the modulation of the human CXCR5 receptor.

Abstract: A device for exercising a user's upper torso that utilizes a minimum of space. A wheeled housing is provided with a handle member providing an effective grip to a user who will lean his or her body's weight against the device is coupled to one or more of the wheels to display the amount of rotation of the wheels thereby giving an indication to a user of the amount of exercise undertaken. A reader of the movement of the device has an output connected to a counter/display that is resettable. The reader is mounted in a spring loaded cavity so that an effective outwardly force brings its ball member in contact with the surface.