Abstract: The disclosure relates to an anti-Pseudomonas PSL binding molecule and uses thereof, in particular, in prevention and treatment of Pseudomonas infection. Furthermore, the disclosure provides compositions and methods for preventing and treating Pseudomonas infection.

Abstract: Cell penetrating suppressor of cytokine signaling (CP-SOCS) molecules engineered to be resistant to intracellular degradation are discussed. Methods of treating diseases associated with cytokine signaling include one or more CP-SOCS degradation resistant molecules.

Abstract: Sigma-delta modulators and a method of modulating are disclosed in which a first sigma-delta modulator having a first quantizer is provided, and a second quantizer is also provided. At least a first node of the first sigma-delta modulator upstream of the first quantizer and a second node of the first sigma-delta modulator upstream of the first quantizer to the second quantizer are coupled together.

Abstract: A quantizer for a sigma delta modulator comprising at least one preliminary stage V1, V2), the quantizer quantizing an input signal (EQ) present at it in accordance with at least one threshold signal (yth,i) and outputting it as a result value (yQ) at a digital result output (OUT), wherein the quantizer has a number of comparators (5j) corresponding to the number of threshold signals (yth,j), which compare the input signal (EQ) with the respective threshold signal (yth,j), the threshold signal being reduced or increased by a correction voltage (ydac3) or a correction current, the correction voltage or correction current being generated in accordance with the result value (yQ) output at the result output (OUT).

Abstract: The invention relates of administration of an attenuated Salmonella strain expressing a lipopolysaccharide O antigen from a suitable pathogen, in particular Pseudomonas aeruginosa, and the use of the same as a vaccine to promote sterile immunity to the pathogen, e.g., P. aeruginosa, via intranasal vaccination. In one embodiment, the present invention is directed to a unique intranasal route of immunization for the delivery of relevant heterologous polysaccharide antigens via a live, attenuated Salmonella strain.

Abstract: Programmable echo cancellation filter for echo signal cancellation for a transceiver having a signal input (13) for receiving the transmission signal emitted by the transceiver (1), an input resistor (36) connected to the signal input (13), an operational amplifier (39), whose signal input (38) is connected to the input resistor (36) and whose signal output (41) is connected to an output resistor (43), a first programmable resistor circuit (48), which is provided between the signal output (41) of the operational amplifier (39) and the signal input (38) of the operational amplifier, a second programmable resistor circuit (51), which is provided between the output resistor (43) and a signal output (15) of the echo cancellation filter (14), a third programmable resistor circuit (55) which is provided between the first programmable resistor circuit (48) and the signal output (15) of the echo cancellation filter (14), the programmable resistor circuits (48, 51, 55) each having a plurality of resistors (65) which a

Abstract: A quantizer for a sigma delta modulator comprising at least one preliminary stage V1, V2), the quantizer quantizing an input signal (EQ) present at it in accordance with at least one threshold signal (yth,i) and outputting it as a result value (yQ) at a digital result output (OUT), wherein the quantizer has a number of comparators (5j) corresponding to the number of threshold signals (yth,j), which compare the input signal (EQ) with the respective threshold signal (yth,j) , the threshold signal being reduced or increased by a correction voltage (ydac3) or a correction current, the correction voltage or correction current being generated in accordance with the result value (yQ) output at the result output (OUT).

Abstract: Programmable echo cancellation filter for echo signal cancellation for a transceiver having a signal input (13) for receiving the transmission signal emitted by the transceiver (1), an input resistor (36) connected to the signal input (13), an operational amplifier (39), whose signal input (38) is connected to the input resistor (36) and whose signal output (41) is connected to an output resistor (43), a first programmable resistor circuit (48), which is provided between the signal output (41) of the operational amplifier (39) and the signal input (38) of the operational amplifier, a second programmable resistor circuit (51), which is provided between the output resistor (43) and a signal output (15) of the echo cancellation filter (14), a third programmable resistor circuit (55), which is provided between the first programmable resistor circuit (48) and the signal output (15) of the echo cancellation filter (14), the programmable resistor circuits (48, 51, 55) each having a plurality of resistors (65) which