Patents by Inventor Antonio Esteve-Subirana

Antonio Esteve-Subirana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4267334
    Abstract: The invention concerns 6-methoxy-2-acetylnaphthalene oxime derivatives of the general formula ##STR1## in which R.sub.1 and R.sub.2 each represent a lower alkyl radical, or form, in association with the nitrogen atom to which they are linked, a saturated heterocyclic group, and the acid addition salts thereof with physiologically acceptable acids. These derivatives have analgesic, antipyretic and anti-inflammatory activity and can be made up into pharmaceutical compositions in tablet, capsule, suppository and the like forms. The derivatives of the invention may be prepared by reacting the corresponding 2-acetyl-6-methoxynaphthalene oximes with an appropriate substituted halogeno-ethylamine.
    Type: Grant
    Filed: July 20, 1979
    Date of Patent: May 12, 1981
    Assignee: Productos Esteve Internacional S.A.
    Inventor: Antonio Esteve Subirana
  • Patent number: 4216214
    Abstract: Novel derivatives of formula (I) and the pharmaceutically acceptable salts thereof. ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each is a lower alkyl group, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached, form a saturated heterocyclic group optionally containing, in addition to the said nitrogen atom, a second hetero atom, a process for the preparation thereof, and their use as anti-histamine anti "H.sub.2 " agents.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: August 5, 1980
    Assignee: PRODESIN (Productos Esteve Internacional S.A.)
    Inventors: Antonio Esteve Subirana, Jose Esteve Soler
  • Patent number: 4115648
    Abstract: Mono- and diesters of 2,5-dihydroxy benzene sulfonic acid are represented by one of the following formulae: ##STR1## wherein R and R' can be identical or different and represent an alkanyl, arylalkanoyl, aryloxyalkanoyl, aryl, alkanesulfonyl, arenesulfonyl, alkylarenesulfonyl or arylalkanesulfonyl radical, B represents the cation of an alkali metal, alkaline-earth metal of ammonia or an unsubstituted or substituted, open chain or cyclic amine, and are remarkable for their hypocholesterolemic, hypotriglycidemic and hypolipidemic activity.
    Type: Grant
    Filed: October 28, 1975
    Date of Patent: September 19, 1978
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventor: Antonio Esteve-Subirana
  • Patent number: 4038390
    Abstract: Salts of p-dihydroxy benzene disulfonic acids having the general formula: ##STR1## wherein B is an alkali metal or an equivalent of an alkaline-earth metal, or BH is the cation of ammonia or a nitrogen containing basic organic compound, are useful for reducing the average bleeding time and for combating capillary fragility.
    Type: Grant
    Filed: August 4, 1975
    Date of Patent: July 26, 1977
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventor: Antonio Esteve-Subirana
  • Patent number: 4031240
    Abstract: Mono- and diesters of 2,5-dihydroxy benzene sulfonic acid are represented by the following formula: ##STR1## wherein each R residue is hydrogen or the residue of p-chlorophenoxy isobutyric acid having the formula: ##STR2## with the proviso that both Rs are not hydrogen simultaneously, and B is hydrogen or the equivalent of an inorganic or organic cation, these compounds are remarkable for their hypocholesterolemic, hypotriglycidemic and hypolipidemic activity.
    Type: Grant
    Filed: September 12, 1975
    Date of Patent: June 21, 1977
    Assignee: Laboratorios del Dr. Esteve S.A.
    Inventor: Antonio Esteve-Subirana
  • Patent number: 4005220
    Abstract: Novel salts of substituted hydroquinone sulfonic acid having the general formula: ##STR1## in which R denotes ammonium or a cation of an organic base such as alkylamines, alkanolamines, arylamines, alkylarylamines, aralkylamines and cyclamines, or a cation of an alkali or alkaline earth metal such as lithium, sodium, potassium, magnesium or calcium. The structure of course depends on the valency of R. In every case, R' denotes a linear or branched alkyl group with 1 to 6 carbon atoms. These salts are used as haemostatic agents and protective agents against capillary fragility.
    Type: Grant
    Filed: April 3, 1975
    Date of Patent: January 25, 1977
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventor: Antonio Esteve-Subirana
  • Patent number: 3954767
    Abstract: Mono- and diesters of 2,5-dihydroxy benzene sulfonic acid are represented by one of the following formulae: ##SPC1##Wherein R and R' can be identical or different and represent an alkanyl, arylalkanoyl, aryloxyalkanoyl, aryl, alkanesulfonyl, arenesulfonyl, alkylarenesulfonyl or arylalkanesulfonyl radical, B represents the cation of an alkali metal, alkaline-earth metal of ammonia or an unsubstituted or substituted, open chain or cyclic amine, and are remarkable for their hypocholesterolemic, hypotriglycidemic and hypolipidemic activity.
    Type: Grant
    Filed: September 13, 1974
    Date of Patent: May 4, 1976
    Inventor: Antonio Esteve-Subirana
  • Patent number: 3947448
    Abstract: Salts of p-dihydroxy benzene disulfonic acids having the general formula: ##SPC1##Wherein B is an alkali metal or an equivalent of an alkaline-earth metal, or BH is the cation of ammonia or a nitrogen containing basic organic compound, are useful for reducing the average bleeding time and for combating capillary fragility.
    Type: Grant
    Filed: December 26, 1973
    Date of Patent: March 30, 1976
    Assignee: Laboratorios Del Dr. Esteve SA
    Inventor: Antonio Esteve-Subirana