Patents by Inventor Antonio ESTRELLA

Antonio ESTRELLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240023589
    Abstract: Solid formulations include a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution: D [3,2] in the range of from 0.6 to 1.5 ?m and D [v, 0.5] in the range of from 1.1 to 3.5 ?m, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. The solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets and surprisingly show a low compression loss.
    Type: Application
    Filed: September 27, 2023
    Publication date: January 25, 2024
    Inventors: Antonio ESTRELLA, Elger FUNDA, Zdravka MISIC, Christian SCHAEFER, Markus Ivo BECK, Bernd SCHLEGEL, Kai URBAN
  • Publication number: 20220071237
    Abstract: Beverages are provided which include a beverage liquid and granules mixed with the beverage liquid The granules include: (i) a milled carotenoid consisting of lutein and/or zeaxanthin, wherein the milled carotenoid has the following particle size distribution: D [3,2] in the range of from 0.6 to 1.5 ?m, and D [v, 0.5] in the range of from 1.1 to 3.5 ?m, (ii) a matrix material which encapsulates the milled carotenoid and comprises at least one modified food starch, a glucose syrup and sucrose, and (iii) a water-soluble antioxidant, wherein the granules have the following particle size distribution: D [3,2] in the range of from 200 to 300 ?m, and D [v, 0.5] in the range of from 220 to 320 ?m, and wherein all D values are as measured by laser diffraction according to the Fraunhofer scattering model, and wherein the granules do not include an oil or a gelatin.
    Type: Application
    Filed: November 17, 2021
    Publication date: March 10, 2022
    Inventors: Markus BECK, Antonio ESTRELLA, Elger FUNDA, Andrea HITZFELD, Christian SCHAEFER, Bernd SCHLEGEL, Kai URBAN
  • Publication number: 20190098924
    Abstract: The present invention is directed towards a solid formulation comprising a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution: D [3, 2] in the range of from 0.6 to 1.5 ?m and D [v, 0.5] in the range of from 1.1 to 3.5 ?m, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. This solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets. Surprisingly these tablets show a low compression loss.
    Type: Application
    Filed: April 3, 2017
    Publication date: April 4, 2019
    Inventors: Antonio ESTRELLA, Elger FUNDA, Zdravka MISIC, Christian SCHAEFER, Markus Ivo BECK, Bernd SCHLEGEL, Kai URBAN
  • Publication number: 20190090517
    Abstract: The present invention is directed towards the use of granules in beverages, wherein the granules comprise (i) a milled carotenoid selected from the group consisting of lutein and zeaxanthin and any mixture thereof having the following particle size distribution: D [3,2] in the range of from 0.6 to 1.5 ?m, and D [v, 0.5] in the range of from 1.1 to 3.5 ?m, and (ii) a matrix comprising at least one modified food starch, a glucose syrup and sucrose, (iii) a water-soluble antioxidant, wherein the granules have the following particle size distribution: D [3,2] in the range of from 200 to 300 ?m, and D [v, 0.5] in the range of from 220 to 320 ?m, all D values as measured by laser diffraction according to the Fraunhofer scattering model, whereby the milled carotenoid is encapsulated by the matrix. The present invention is also directed towards the beverages and the granules as such, as well as to a process for the manufacture of the granules. Preferably the carotenoid is lutein, zeaxanthin or any mixture thereof.
    Type: Application
    Filed: April 3, 2017
    Publication date: March 28, 2019
    Applicant: DSM IP Assets B.V.
    Inventors: Markus BECK, Antonio ESTRELLA, Elger FUNDA, Andrea HITZFELD, Christian SCHAEFER, Bernd SCHLEGEL, Kai URBAN
  • Patent number: 8859228
    Abstract: The invention relates to a novel method for the production of ?-carotene from submerged cultures of mucoral fungi such as Blakeslea, Choanephora or Phycomyces by adding lectin to the culture medium and performing pH control once fermentation has started. The method involves ?-carotene recovery stage that makes it possible to simplify the process, optimize yields and increase purification of the product.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: October 14, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Javier Costa Perez, Antonio Estrella Castro, Ana Teresa Marcos Rodriguez, J. Emiliano Gonzalez De Prado, Enrique R. Peiro Cezon, Alfonso Collados De La Vieja, Manuel Esteban Morales
  • Patent number: 7799540
    Abstract: The method of fermentation with selected strains of B. trispora described in the present invention makes it possible to achieve lycopene yields higher than those currently described. The methods of isolation, purification and formulation are applicable to any natural source of lycopene, especially to submerged cultures of mucoral fungi of the genera Blakeslea, Choanephora, Phycomyces or Mucor. The method of extraction makes it possible to simplify the recovery process and increase the purity of the product, relative to the methods previously described. The methods of formulation provide high added value, since they make it possible to obtain stabilized preparations of lycopene for direct application in the food and pharmaceutical fields.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: September 21, 2010
    Assignee: Vitatene, S.A.
    Inventors: Ana Teresa Marcos Rodríguez, Antonio Estrella De Castro, Javier Costa Perez, Manuel Antonio Oliver Ruiz, Nieves Fraile Yecora, Juan Luis De La Fuente Moreno, Marta Rodríguez Saiz, Bruno Diez Garcia, Enrieque Peiro Cezon, Angel Muñoz Ruiz, Walter Cabri, Juan Francisco Lopez Ortiz, José Luis Barredo Fuente
  • Patent number: 7045643
    Abstract: The present invention describes a method of preparation of formulations of microcrystalline lutein, particularly in the form of esters, which are resistant to oxidation and are soluble in hydrophilic and/or lipophilic media. For these formulations, the esters of lutein are mixed with antioxidants, vegetable oils and/or organic solvents, and this initial mixture is submitted to various stages depending on the type of final formulation required. These formulations are suitable for direct application as colourants in the pharmaceutical, food and cosmetics fields. They can also be used as diet supplements.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: May 16, 2006
    Assignee: Vitatene, S.A.
    Inventors: Antonio Estrella De Castro, Nieves Fraile Yecora, Manuel Oliver Ruiz, Angel Muñoz, Juan Francisco Lopez Oritz, Walter Cabri
  • Publication number: 20050106657
    Abstract: The method of fermentation with selected strains of B. trispora described in the present invention makes it possible to achieve lycopene yields higher than those currently described. The methods of isolation, purification and formulation are applicable to any natural source of lycopene, especially to submerged cultures of mucoral fungi of the genera Blakeslea, Choanephora, Phycomyces or Mucor. The method of extraction makes it possible to simplify the recovery process and increase the purity of the product, relative to the methods previously described. The methods of formulation provide high added value, since they make it possible to obtain stabilized preparations of lycopene for direct application in the food and pharmaceutical fields.
    Type: Application
    Filed: December 20, 2002
    Publication date: May 19, 2005
    Inventors: Ana Marcos Rodriguez, Antonio Estrella De Castro, Javier Costa Perez, Manuel Oliver Ruiz, Nieves Fraile Yecora, Juan De La Fuente Moreno, Marta Saiz, Bruno Diez Garcia, Enrieque Peiro Cezon, Angel Ruiz, Walter Cabri, Juan Lopez Ortiz, Jose Barredo Fuente
  • Publication number: 20050079223
    Abstract: The present invention describes a method of preparation of formulations of microcrystalline lutein, particularly in the form of esters, which are resistant to oxidation and are soluble in hydrophilic and/or lipophilic media. For these formulations, the esters of lutein are mixed with antioxidants, vegetable oils and/or organic solvents, and this initial mixture is submitted to various stages depending on the type of final formulation required. These formulations are suitable for direct application as colourants in the pharmaceutical, food and cosmetics fields. They can also be used as diet supplements.
    Type: Application
    Filed: December 20, 2002
    Publication date: April 14, 2005
    Inventors: Antonio Estrella De Castro, Nieves Fraile Yecora, Manuel Oliver Ruiz, Angel Muñoz, Juan Lopez Ortiz, Walter Cabri
  • Publication number: 20040067550
    Abstract: The invention relates to a novel method for the production of &bgr;-carotene from submerged cultures of mucoral fungi such as Blakeslea, Choanephora or Phycomyces by adding lectin to the culture medium and performing pH control once fermentation has started. The method involves &bgr;-carotene recovery stage that makes it possible to simplify the process, optimize yields and increase purification of the product.
    Type: Application
    Filed: November 6, 2003
    Publication date: April 8, 2004
    Inventors: Javier Costa Perez, Antonio Estrella Castro, Ana Teresa Marcos Rodriguez, J Emiliano Gonzalez De Prado, Enrique R Peiro Cezon, Alfonso Collados De La Vieja, Manuel Esteban Morales