Abstract: The present invention relates to pharmaceutical compositions suitable for oral administration comprising 5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol (branaplam) and a pharmaceutically acceptable cyclodextrin.

Abstract: A drill rod for breaking up the edge of a hole comprises a cylindrical body, a buffer and injector nozzles. The drill rod injects air and water through its injector nozzles at the material deposited at the edge of the hole, thus achieving the breaking up thereof without the need to use auxiliary equipment or manual operations. A method for breaking up the edge of a hole is described, including using a rod to break up the edge of a hole, and comprising the stages necessary to perform this operation using a drill.

Abstract: The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.

Abstract: Provided herein are systems and methods for a perception and feeling tool having multiple modules configured to allow participants to express perceptions and feelings at one or more moments during, for example, a study. The perception and feeling tool can be configured to record the participants' perceptions and feelings at the one or more moments during the study as collected data, as well as display results for any one or more of the participants or an aggregate of all the participants for the perceptions and the feelings at the one or more moments. A collection module can be configured to collect raw data including the participants' perceptions and feelings. One or more analytical modules can be configured to apply analytics to the raw data. One or more servers can be configured to deliver user interfaces to the participants and allow the participants to express the study.

Abstract: The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.

Abstract: A permanently magnetizable rotor having a central rotor structure including a rotor shaft supporting a cylindrical backiron. The rotor further includes a multi-pole structure comprising circumferentially alternating pole elements, and a rotor cover extending longitudinally over the multi-pole structure. The rotor additionally includes an endcap including an engagement surface positioned in engagement with an end of the backiron. The endcap defines first and second anti-rotation features for preventing circumferential rotation of one or more of the pole elements about the backiron. The first anti-rotation feature is configured differently than the second anti-rotation feature and each anti-rotation feature defines a torque transmitting feature for transmitting a torque from different locations on the multi-pole structure.

Abstract: A system and method for generating a ghost profile is disclosed. The ghost profile allows a user to use certain features in a social network without converting to a social network profile. Specifically, the ghost profiles are unsearchable and comments that originate from a ghost profile user are displayed as partial names. The ghost profile is generated when a member of the social network invites a user to join. In one example, the member is automatically added as a friend to the user's ghost profile.

Abstract: A hose clamp has a flexible strap fittable around a hose and having opposite ends, a strap end part separate from the strap, and a mechanism for increasing or reducing the effective length of the strap. This mechanism is between one of the ends of the strap and the strap end part. A spring element separate from the strap and strap end part has one end linked to the strap and another end linked to the strap end part so as to provide a spring force in the circumferential direction of the strap.

Abstract: A permanently magnetizable rotor having a central rotor structure including a rotor shaft supporting a cylindrical backiron. The rotor further includes a multi-pole structure comprising circumferentially alternating pole elements, and a rotor cover extending longitudinally over the multi-pole structure. The rotor additionally includes an endcap including an engagement surface positioned in engagement with an end of the backiron. The endcap defines first and second anti-rotation features for preventing circumferential rotation of one or more of the pole elements about the backiron. The first anti-rotation feature is configured differently than the second anti-rotation feature and each anti-rotation feature defines a torque transmitting feature for transmitting a torque from different locations on the multi-pole structure.

Abstract: The field of this invention relates to supramolecular functional materials, particularly to coordination networks, more particularly to coordination polymers, more particularly to metal based one-dimensional coordination polymers. The metal based one-dimensional coordination polymers comprises a repeat unit [L1-M-L2]n where L1 and L2 are one of a plurality of carboxylate ligands and L1 can be the same as L2, M is a metal, particularly a transition metal, and n is an integer from 1 to infinity. The metal based one-dimensional coordination polymers display one or more physico-chemical properties giving at least one functionality to the supramolecular material.

Abstract: A system and method for generating a ghost profile is disclosed. The ghost profile allows a user to use certain features in a social network without converting to a social network profile. Specifically, the ghost profiles are unsearchable and comments that originate from a ghost profile user are displayed as partial names. The ghost profile is generated when a member of the social network invites a user to join. In one example, the member is automatically added as a friend to the user's ghost profile.

Abstract: The field of this invention relates to supramolecular functional materials, particularly to coordination networks, more particularly to coordination polymers, more particularly to metal based one-dimensional coordination polymers. The metal based one-dimensional coordination polymers comprises a repeat unit [L1-M-L2]n where L1 and L2 are one of a plurality of carboxylate ligands and L1 can be the same as L2, M is a metal, particularly a transition metal, and n is an integer from 1 to infinity. The metal based one-dimensional coordination polymers display one or more physico-chemical properties giving at least one functionality to the supramolecular material.

Abstract: The invention relates to a Hose clamp comprising a flexible strap (1) to be placed around a hose, a mechanism (2,3) for increasing or reducing the effective length of the strap (1), the mechanism (2,3) being fixed to one part/end (1a) of the strap (1) and driving the other part/end (1 b, 1c) of the strap (1), in which at least one part/area of the strap (1) is formed as a spring element (5), in particular providing a spring force in the circumferential direction of the strap (1).

Abstract: A device for stabilizing the position of an infant while sleeping features a shell assembly including a base panel having two longitudinal sides and two lateral sides, an end wall extending generally upwardly from one of the lateral sides, two side walls extending generally upwardly from the longitudinal sides, a shell cover comprising an outer surface and conforming generally to the shell assembly, and a removable postioner insert disposed atop the base panel and comprising left and right nacelles attached to an insert base and separated by a distance selected to accommodate the width of an infant placed between the nacelles, to inhibit lateral motion of the infant while sleeping.

Abstract: Disclosed are methods and compositions for defoaming alcoholic fermentations. An aqueous composition of polydimethylsiloxane, an ethylene oxide/propylene oxide block copolymer and a silicone/silica blend is employed to treat the fermentation for foaming.

Abstract: A sturdy collapsible wooden TV/sofa table for use with a chair, couch or sofa, comprising of a foldable tabletop and folding t-shaped leg supports. The foldable tabletop comprises of two coplanar pieces mounted together by two hinges. One of the coplanar portions is a great deal smaller than the other thus allowing for the tabletop to fold into a parallel position against its leg supports when in the collapsed form. The leg supports are also mounted pivotally to each other by two hinges. One leg is mounted perpendicular to the tabletop piece while the other is hinged lengthwise to the middle of the longer portion of the tabletop and folds parallel to it when in the collapsed position. The movable hinged leg is designed to hold the tabletop in the upright position when in use, where it is fastened to a finger latch located underneath the tabletop. The finger latch keeps the leg from moving from its t-shaped position while in the upright position.

Abstract: Methods and compositions for clarifying sugar are disclosed. Compositions of a condensation polymer of a dihaloalkyl compound and a dialkylamine compound and a phosphate compound are effective at clarifying the sugar syrup during its production as well as reducing the total amount of phosphate used.

Abstract: An improved process for clarifying sugar syrup in the flotation system of a sugar making operation. Neutral phosphate-based compounds are added to the flotation system to aid in clarifying the sugar syrup. The use of the neutral phosphate-based compounds will eliminate the use of phosphoric acid and the commensurate need for neutralizing chemical as well as elimination of the tanks for phosphoric acid and neutralizing chemical mixing at field installations.

Abstract: Disclosed are methods and compositions for defoaming alcoholic fermentations. An aqueous composition of polydimethylsiloxane, an ethylene oxide/propylene oxide block copolymer and a silicone/silica blend is employed to treat the fermentation for foaming.