Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: The use of pectins and/or polymers to prevent nicotine oxidation in tobacco containing products is disclosed. These polymers may be naturally occurring anionic polymers or synthetic polymers. These pectins and/or polymers prevent nicotine from oxidizing into cotinine, nicotine-cis-N-oxide, nicotine-trans-N-oxide, and/or nicotine-1,1-di-N-oxide. Molluscicides, algaecides, pesticides, and stabilized nicotine compositions comprising nicotine and pectin, anionic polymers, or combinations thereof are disclosed.

Abstract: A device and method for real-time measurement using acoustic wave sensors, without the measurement being altered by environmental conditions such as temperature, humidity, flow or pressure, and without requiring the use of external gauges. The proposed method and device improve the stability and detection limit of quartz crystal microbalance (QCM) sensors. The method and device are based on the high degree of correlation between acoustic resonators integrated into a single piezoelectric substrate. The use of a reference sample to correct the instability of the baseline is not required. The method and device are intended for the industrial sector of the production of measuring devices based on quartz crystals.

Abstract: In one aspect, the present invention comprises providing an additive or aggregate to be applied directly to one or more of the components of a ceramic coating and which is constituted by carbonate apatites particles which are maintained as aggregates within a matrix of silicoaluminates at firing temperatures of the ceramic coatings, where the main function of these aggregates is to provide the ceramic coating properties selected from the group comprising: low effusivity, wear resistance, resistance to chemical attack and resistance to staining. In other aspects, the present invention comprises providing a ceramic coating incorporating said additive and a method for providing a ceramic coating with properties selected from the group comprising: low effusivity, wear resistance, resistance to chemical attack and resistance to staining.

Abstract: The embodiment relates to the convenient amateur creation of a beverage where the extraction of flavor into a solvent is obtained using ultrasound. Where the solvent and solute are held in a removable carafe which has an ultrasound transducer. A control system will trigger ultrasound into the solvent for specific durations in order to quickly create the desired outcome. The use of one or more computers that will be able to implement a recipe, control the machine, and interact with the user ensure that the end user is able to operate the machine easily.

Abstract: The invention relates to small photosensitizers, their process of preparation and uses of the compounds in optical imaging and photodynamic therapy. The invention provides a compound of formula (I), a derivative or a salt thereof Wherein R1 is selected from the group consisting of amines, anilines, phenols, thiophenols, selenols and aryl groups; R2 and R3 independently are H or halogen; R4 is selected from the group consisting of H, nitro and cyano: and R5 and R6 independently are either absent or oxygen or methyl.

Abstract: Provided herein are enhanced systems for potentiating cell-mediated oncolytic viral therapy. Also provided are modified viruses for such systems, and methods of treatment of cancers by administering such systems.

Abstract: A device for sealing a telecommunications cable is disclosed. The device includes a first part, and a second part having one or more attachment members that assemble onto the first part to assemble the first and second parts together. A cavity is defined between the first and second parts that extends along a central axis and between first and second ends of the device. The cavity is structured to seal the cable between the first and second parts without threading the cable through the first and second ends, and the first and second parts define at least one mounting location for a cable port in a telecommunications enclosure. The cavity may receive a resin to seal the cable between the first and second parts.

Abstract: Provided herein are enhanced systems for potentiating cell-mediated oncolytic viral therapy. Also provided are modified viruses for such systems, and methods of treatment of cancers by administering such systems.

Abstract: The accuracy of existing machine learning models, software technologies, and computers are improved by using one or more machine learning models to map data inside structural elements, such as rows or columns, as found within a document to data objects of other documents, where the data objects are at least partially indicative of candidate categories that the data can belong to.

Abstract: A method for generating a training data set to train an artificial intelligence module for assisting air traffic control, including the steps of providing a first layer of historical flight data comprising trajectory data of aircraft, the trajectory data comprising track data, flight level data or speed data along time steps (t) of the trajectory, detecting a change in the trajectory data, the change occurring at a time step t2 along the trajectory, in either track data, flight level data or speed data of at least an aircraft, labelling, by a labelling module, in a time or distance t1 located before t2 in the trajectory of the aircraft with the detected change such that the detected change is configured to correspond with an instruction given by an air traffic controller to the aircraft, the labelled historical flight data generating a training data set for the artificial intelligence module.

Abstract: The present invention relates to resist compostions, in particular to photoresists that can be used in photolithography, especially in the fabrication of integrated circuits and derivative products. The resist compositions of the invention include an anti-scattering component which has a significant amount of empty space, and thus fewer scattering centers, such that radiation-scattering events are more limited during exposure. Such anti-scattering effects can lead to improved resolutions by reducing the usual proximity effects associated with lithographic techniques, allowing the production of smaller, higher resolution microchips. Furthermore, certain embodiments involve anti-scattering components which are directly linked to the resist components, which can improve the overall lithographic chemistry to provide benefits both in terms of resolution and resist sensitivity.

Abstract: Compounds of general formula wherein the wavy bond ˜ is either a double bond or the epoxide, or pharmaceutically acceptable salts, solvates, tautomers, or stereoisomers thereof, for use in the treatment of diseases associated with oxidative stress.

Abstract: The invention relates to small photosensitizers, their process of preparation and uses of the compounds in optical imaging and photodynamic therapy. The invention provides a compound of formula (I), a derivative or a salt thereof Wherein R1 is selected from the group consisting of amines, anilines, phenols, thiophenols, selenols and aryl groups; R2 and R3 independently are H or halogen; R4 is selected from the group consisting of H, nitre and cyano: and R5 and R6 independently are either absent or oxygen or methyl.

Abstract: The invention relates to small, conjugatable, orthogonal and tunable fluorophores for imaging of small bioactive molecules. The invention further relates to processes for the preparation of the compounds, and uses of the compounds in therapeutic, diagnostic, surgery and analytical applications. The invention provides a compound of formula (I), a derivative or a salt thereof. Wherein X is selected from the group consisting of NH, O, S, SeR5R6, CR7R8; R1 is selected from the group consisting of amines, alcohols, thiols, thiophenols, selenols, selenophenols and aryl groups; R2 and R3 are independently H or a halogen; R4 tis either H, nitro or cyano; R5 is either absent or methyl or oxygen; R6 is either absent or methyl or oxygen; and R7 and R8 are independently selected from the group consisting of linear or cyclic alkyl groups containing halogen, amino, cyano or carboxylic ester substituents, and alkyl aryl groups.

Abstract: The machine comprises: manufacturing robots (201) to fabricate parts 1506 through additive manufacturing; and an automatic loading system (401) of manufacturing platforms (404), to feed the manufacturing robot or robots (201) with manufacturing platforms 404 designed to support parts during manufacturing and manufactured parts 1506. The loader is located beside each manufacturing robot (201) to load the manufacturing platforms. The lateral external location of the loader with respect to the manufacturing robot (201) permits the integration of a heating system inside the robot to heat the manufacturing platform when the platform is loaded, giving rise to the possibility of printing in different materials such as technical polymers, metals, and ceramics; furthermore, having the loading system outside of the robotic arm, one single loader could feed several adjacent robotic arms.

Abstract: The present invention relates to resist compostions, in particular to photoresists that can be used in photolithography, especially in the fabrication of integrated circuits and derivative products. The resist compositions of the invention include an anti-scattering component which has a significant amount of empty space, and thus fewer scattering centers, such that radiation-scattering events are more limited during exposure. Such anti-scattering effects can lead to improved resolutions by reducing the usual proximity effects associated with lithographic techniques, allowing the production of smaller, higher resolution microchips. Furthermore, certain embodiments involve anti-scattering components which are directly linked to the resist components, which can improve the overall lithographic chemistry to provide benefits both in terms of resolution and resist sensitivity.

Abstract: In one aspect, the present invention comprises providing an additive or aggregate to be applied directly to one or more of the components of a ceramic coating and which is constituted by carbonate apatites particles which are maintained as aggregates within a matrix of silicoaluminates at firing temperatures of the ceramic coatings, where the main function of these aggregates is to provide the ceramic coating properties selected from the group comprising: low effusivity, wear resistance, resistance to chemical attack and resistance to staining. In other aspects, the present invention comprises providing a ceramic coating incorporating said additive and a method for providing a ceramic coating with properties selected from the group comprising: low effusivity, wear resistance, resistance to chemical attack and resistance to staining.

Abstract: The use of pectins and/or polymers to prevent nicotine oxidation in tobacco containing products is disclosed. These polymers may be naturally occurring anionic polymers or synthetic polymers. These pectins and/or polymers prevent nicotine from oxidizing into cotinine, nicotine-cis-N-oxide, nicotine-trans-N-oxide, and/or nicotine-1,1-di-N-oxide. Molluscicides, algaecides, pesticides, and stabilized nicotine compositions comprising nicotine and pectin, anionic polymers, or combinations thereof are disclosed.

Abstract: The use of pectins and/or polymers to prevent nicotine oxidation in tobacco containing products is disclosed. These polymers may be naturally occurring anionic polymers or synthetic polymers. These pectins and/or polymers prevent nicotine from oxidizing into cotinine, nicotine-cis-N-oxide, nicotine-trans-N-oxide, and/or nicotine-1,1-di-N-oxide. Molluscicides, algaecides, pesticides, and stabilized nicotine compositions comprising nicotine and pectin, anionic polymers, or combinations thereof are disclosed.