Abstract: Systems and methods of synthetic flight performance data generation include obtaining training data corresponding to multiple timeseries of multivariate aircraft performance data of actual aircraft flights. The systems and methods also include performing a training operation of a generative adversarial network that includes a synthetic aircraft performance data generator and a discriminator. After completion of the training operation, the systems and methods also include receiving one or more input parameters, and generating, at the synthetic aircraft performance data generator, one or more timeseries of synthetic aircraft performance data based on the one or more input parameters.

Abstract: A device includes a processor configured to obtain flight data of one or more aircraft of an aircraft type. The processor is configured to identify a first portion of the flight data as first phase flight data associated with a first phase of one or more flights of the one or more aircraft, and to apply a first aircraft performance model to the first phase flight data to determine first parameter values. The processor is configured to identify a second portion of the flight data as second phase flight data associated with a second phase of the one or more flights, and to apply the first aircraft performance model to the second phase flight data to determine second parameter values. The processor is configured to generate, based on the first parameter values and the second parameter values, a second aircraft performance model of a particular aircraft of the aircraft type.

Abstract: The present invention describes a pharmaceutical composition whose active ingredient includes conjugates of membrane vesicles of Neisseria meningitidis and the GM3 ganglioside in a conjugation ratio in excess of proteins, has particular characteristics of size, surface charge and a morphology associated with nano-particulate systems that give it advantageous properties as an immunomodulator, because it induces a convenient and significant reduction of myeloid-derived suppressor cells that has an impact on the response of T lymphocytes and on the survival of patients with tumors. The invention further discloses the use of the pharmaceutical composition disclosed in the treatment of cancer, particularly those cancers where the myeloid-derived suppressor cells (MDSCs) are high; as well as a method of treatment with said composition in cancer patients and a method to select those who will receive said treatment.

Abstract: Example implementations relate to a method to manage printhead operational life; the method comprising firing at least one nozzle of a printhead according to an associated firing parameter to produce a respective drop of print liquid, measuring a parameter associated with the drop of print liquid, and adjusting the firing parameter in response to the measuring to reduce the measured parameter associated with the drop of print liquid on a subsequent firing while maintaining the firing parameter at or above a predetermined parameter limit to maintain print image quality.

Abstract: The present invention describes a pharmaceutical composition whose active ingredient includes conjugates of membrane vesicles of Neisseria meningitidis and the GM3 ganglioside in a conjugation ratio in excess of proteins, has particular characteristics of size, surface charge and a morphology associated with nano-particulate systems that give it advantageous properties as an immunomodulator, because it induces a convenient and significant reduction of myeloid-derived suppressor cells that has an impact on the response of lymphocytes and on the survival of patients with tumors. The invention further discloses the use of the pharmaceutical composition disclosed in the treatment of cancer, particularly those cancers where the myeloid-derived suppressor cells (MDSCs) are high; as well as a method of treatment with said composition in cancer patients and a method to select those who will receive said treatment.

Abstract: The present disclosure relates to methods and devices for performing print control. In an example there is disclosed a control method. The control method may comprise programming a print mask to instruct printhead nozzles on a moveable carriage to deposit a first line of print material on a medium, wherein the print mask controls the depositing so that an edge of an area of the medium on which material is deposited defines a pattern which is repeated along a scan axis of the carriage and which differs in a direction of movement of the medium. The control method may further comprise scanning the first line of print material. The control method may further comprise performing control of subsequent print material depositing or medium advancement, based on the scan.

Abstract: In an example, a printing apparatus includes a controller, wherein the controller may be to compare a historic usage of a first printhead nozzle with a historic usage of a second printhead nozzle which is located on a same printhead as the first nozzle. The controller may be to determine that the historic usage of the first nozzle is higher than the historic usage of the second nozzle, and in response identify a currently operational third printhead nozzle, for which the second nozzle is able to compensate; and turn off the third nozzle, and operate the second nozzle at a higher firing frequency to compensate for the third nozzle.

Abstract: In example implementations, a method, a device, and a program are provided. The method includes detecting a power increase movement of a printer carriage. A location of the printer carriage is detected at a time of the detected power increase. Based on the detected location of the printer carriage, determine whether the print medium is damaged. The device includes a power monitor to detect a power increase during movement of a printer carriage. A locator detects a location of the printer carriage at the time of the detected power increase. A damage determiner determines, based on the detected location of the printer carriage, whether the print medium is damaged. The program detects a power increase during movement of a printer carriage. Location of printer carriage is detected at time of detected power increase. Based on detected location of the printer carriage, it is determined whether the print medium is damaged.

Abstract: Examples relate to a method to print a print job. The method comprise comparing an operational parameter of the print job with a reference operational parameter and determining to perform a maintenance task during the print job based on at least a result of comparing the operational parameter with the reference operational parameter. If the maintenance task is to be performed, the method further comprises determining a safety area on a printable medium and performing a maintenance task on a printable medium.

Abstract: There is disclosed a device, method and program, wherein the method comprises detecting a power increase, during which power usage increases by at least a threshold amount over an expected power usage during movement of a printer carriage over a print medium along a scan axis. The increase method further comprises detecting a location of the printer carriage at a time of the detected power usage increase and determining, based on the detected location of the printer carriage, whether the print medium is damaged.

Abstract: Aspects of the disclosure provide an electronic device comprising a controller. The controller to determine a volume of print fluid in a first tank of the electronic device, monitor current printing conditions of the electronic device disposing print fluid on a substrate, determine, based on the volume of print fluid and the current printing conditions, whether an adverse printing condition exists, responsive to the volume of print fluid being less than a threshold and the adverse printing condition not existing, control a pump to refill the first tank from a second tank at a flow rate determined at least partially according to the determined volume, and responsive to the volume of print fluid being less than the threshold and the adverse printing condition existing, control the pump to refill the first tank from the second tank at a default flow rate determined independent of the determined volume.

Abstract: A system (300) is provided having a printer (4) to print printing liquid onto a web (6) of media (8). The system (300) has a winding roller (10) on which to roll the web (6) of media (8) after printing. A tensioner (12) to vary the tension in a portion (14) of the web (6) of media (8) is also provided. The portion (14) is a portion of web which is being rolled onto the winding roller (10). Also provided is controller (16) to control the tensioner (12) to vary the tension based on the time taken for the printed printing liquid on the web (6) of media (8) to dry.

Abstract: In some examples, a system compares information of a color profile for an imaging device to color information relating to a type of substrate on which an image is to be formed. Based on the comparing, the system determines a mismatch between the color profile and the type of substrate. The system initiates a remedial action to address the mismatch.

Abstract: Examples relate to receiving image data of an image to be sublimation printed, wherein the image data comprising one or more colours to be printed, and a corresponding printing liquid density of the one or more colours. Based on the received image data, a sublimation energy to use to transfer printed printing liquid representing the image into a material is determined, and the determined sublimation energy is provided to a sublimator of a printer for transferring the image.

Abstract: Aspects of the disclosure provide an electronic device comprising a controller. The controller to determine a volume of print fluid in a first tank of the electronic device, monitor current printing conditions of the electronic device disposing print fluid on a substrate, determine, based on the volume of print fluid and the current printing conditions, whether an adverse printing condition exists, responsive to the volume of print fluid being less than a threshold and the adverse printing condition not existing, control a pump to refill the first tank from a second tank at a flow rate determined at least partially according to the determined volume, and responsive to the volume of print fluid being less than the threshold and the adverse printing condition existing, control the pump to refill the first tank from the second tank at a default flow rate determined independent of the determined volume.

Abstract: In an example, a print apparatus includes a printhead carriage to receive a printhead comprising a print agent ejection nozzle, a drop detector to acquire a signal indicative of variations in a parameter detected by the drop detector over a period of drop detection; a memory to store nozzle location information of the nozzles; and processing circuitry comprising a correlation module to correlate the drop detector signal with the nozzle location information wherein the processing circuitry comprises an abnormality detection module to determine, based on an output of the correlation module, a cross-nozzle abnormality that affects a subset of nozzles.

Abstract: A printer includes a print head to print a pixel by ejecting drops of a printing fluid from the print head, and a controller. The controller monitors a drop volume of the printing fluid ejected by the print head. When the drop volume is below a threshold, the controller controls the print head in accordance with a first print mode to increase the frequency of ejecting drops of the printing fluid within the pixel print time with a decrease in the drop volume that maintains a print quality parameter. The controller changes to a second print mode to increase the pixel print time that maintains the print quality parameter.

Abstract: A method of printing, the method comprising: monitoring operation of first nozzles of a first nozzle array, and if malfunction of a number of first nozzles of the first nozzle array is detected, setting a number of second nozzles of a second nozzle array to a compensation mode. Monitoring operation of the number of second nozzles in the compensation mode and, in response to detecting that a printing parameter of the number of second nozzles differs from a reference printing parameter, adjusting an operation mode parameter of a subset of second nozzles.

Abstract: In an example, a printing apparatus includes a controller, wherein the controller may be to compare a historic usage of a first printhead nozzle with a historic usage of a second printhead nozzle which is located on a same printhead as the first nozzle. The controller may be to determine that the historic usage of the first nozzle is higher than the historic usage of the second nozzle, and in response identify a currently operational third printhead nozzle, for which the second nozzle is able to compensate; and turn off the third nozzle, and operate the second nozzle at a higher firing frequency to compensate for the third nozzle.

Abstract: A method for regulating a deposition characteristic of a rendering material in a rendering apparatus includes determining a status of material deposition structure, and adjusting a physical attribute of the material deposition structure.