Patents by Inventor Antonio Lambiase

Antonio Lambiase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates for the treatment of mesothelioma
    Patent number: 9068016
    Abstract: The present invention provides conjugates of cytokines and targeting peptides that is able to bind to a receptor expressed on tumor-associated vessels or to a component of the extracellular matrix associated to the tumor vessels, for treatment of malignant pleural mesothelioma. In particular, the invention provides conjugates comprising the cytokine TNF linked to a peptide containing the NGR motif. The invention further provides pharmaceutical compositions comprising such conjugate and pharmaceutical formulations comprising conjugates dissolved in appropriate buffers.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: June 30, 2015
    Assignee: Molmed S.P.A
    Inventors: Claudio Bordignon, Antonio Lambiase
  • CONJUGATES FOR THE TREATMENT OF MESOTHELIOMA
    Publication number: 20130315856
    Abstract: The present invention provides conjugates of cytokines and targeting peptides that is able to bind to a receptor expressed on tumor-associated vessels or to a component of the extracellular matrix associated to the tumor vessels, for treatment of malignant pleural mesothelioma. In particular, the invention provides conjugates comprising the cytokine TNF linked to a peptide containing the NGR motif. The invention further provides pharmaceutical compositions comprising such conjugate and pharmaceutical formulations comprising conjugates dissolved in appropriate buffers.
    Type: Application
    Filed: January 25, 2013
    Publication date: November 28, 2013
    Applicant: MOLMED S.P.A
    Inventors: Claudio BORDIGNON, Antonio LAMBIASE
  • CONJUGATES FOR THE TREATMENT OF MESOTHELIOMA
    Publication number: 20110263512
    Abstract: The present invention provides conjugates of cytokines and targeting peptides that is able to bind to a receptor expressed on tumor-associated vessels or to a component of the extracellular matrix associated to the tumor vessels, for treatment of malignant pleural mesothelioma. In particular, the invention provides conjugates comprising the cytokine TNF linked to a peptide containing the NGR motif. The invention further provides pharmaceutical compositions comprising such conjugate and pharmaceutical formulations comprising conjugates dissolved in appropriate buffers.
    Type: Application
    Filed: May 12, 2009
    Publication date: October 27, 2011
    Applicant: MOLMED S.P.A
    Inventors: Claudio Bordignon, Antonio Lambiase