Patents by Inventor Antonio Lerpini

Antonio Lerpini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of cephalosporins
    Patent number: 5625058
    Abstract: The present invention relates to a process for the preparation of 7-(.alpha.-hydroxyacylamino)-3-(1-sulphoalkyl-tetrazol-5-yl-thiomethyl)-3- cephem-4-carboxylic acids and relevant salts, via acylation of a 7-amino-3-(1-sulphoalkyl-tetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acid with the corresponding chloride of .alpha.-formyl oxycarboxylic acid in a diluent, at pH 6.5-7.0; deformylation by treatment with an acid at pH between 0.5 and 1.5; extraction/s with an organic solvent of the acid aqueous phase from deformylation, followed by salting out and extraction with a solvent selected among tetrahydrofuran, methylethylketone, and acetonitrile; solvent evaporation and salification in a non-aqueous medium.
    Type: Grant
    Filed: July 12, 1994
    Date of Patent: April 29, 1997
    Assignee: Farmabios S.r.1.
    Inventors: Artemio Pessa, Antonio Lerpini