Patents by Inventor Antonio Marchini

Antonio Marchini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED PARVOVIRUS USEFUL FOR GENE SILENCING
    Publication number: 20140310829
    Abstract: Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvovirus.
    Type: Application
    Filed: January 25, 2013
    Publication date: October 16, 2014
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM
    Inventors: Antonio Marchini, Jean Rommelaere, Barbara Leuchs, Anna Illarionova
  • ADENO-PARVOVIRUS CHIMERA WITH ENHANCED ONCOLYTICAL POTENTIAL
    Publication number: 20140235699
    Abstract: Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is characterized by deletion of E1 and E3, and (b) the biological activity of the parvoviral protein NS, preferably NS1, is reduced or eliminated.
    Type: Application
    Filed: January 6, 2014
    Publication date: August 21, 2014
    Applicant: Deutsches Krebsforschungszentrum
    Inventors: Nazim El-Andaloussi, Antonio Marchini, Jean Rommelaere
  • Cancer Therapy with a Parvovirus Combined with an HDAC Inhibitor
    Publication number: 20130058899
    Abstract: Described is a pharmaceutical composition comprising (a) a parvovirus and (b) a histone deacetylase inhibitor (HDACI) and the use of said composition for treatment of cancer, e.g., brain tumor, cervical carcinoma, or pancreatic carcinoma.
    Type: Application
    Filed: March 17, 2011
    Publication date: March 7, 2013
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM
    Inventors: Antonio Marchini, Jean Rommelaere, Nazim El-Andaloussi, Georgi Hristov, Junwei Li