Patents by Inventor Antonios Mikos

Antonios Mikos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090291106
    Abstract: A block copolymer containing a) a hydrophobic biodegradable polymer, b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b) is disclosed. Shaped bodies are formed to consist of the block copolymer and are utilized as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
    Type: Application
    Filed: July 17, 2009
    Publication date: November 26, 2009
    Applicant: MAST BIOSURGERY AG
    Inventors: Achim Göpferich, Jörg Tessmar, Michaela Schulz, Torsten Blunk, Antonios Mikos
  • Publication number: 20070299240
    Abstract: The invention relates to a block copolymer containing: a) hydrophobic biodegradable polymer; b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b). The invention relates to shaped bodies consisting of the block copolymer and to their utilization, particularly as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
    Type: Application
    Filed: August 28, 2007
    Publication date: December 27, 2007
    Inventors: Achim Gopferich, Jorg Tessmar, Michaela Schulz, Torsten Blunk, Antonios Mikos
  • Publication number: 20070299227
    Abstract: The invention relates to a block copolymer containing: a) hydrophobic biodegradable polymer; b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b). The invention relates to shaped bodies consisting of the block copolymer and to their utilization, particularly as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
    Type: Application
    Filed: August 28, 2007
    Publication date: December 27, 2007
    Inventors: Achim Gopferich, Jorg Tessmar, Michaela Schulz, Torsten Blunk, Antonios Mikos
  • Publication number: 20070299238
    Abstract: The invention relates to a block copolymer containing: a) hydrophobic biodegradable polymer; b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b). The invention relates to shaped bodies consisting of the block copolymer and to their utilization, particularly as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
    Type: Application
    Filed: August 28, 2007
    Publication date: December 27, 2007
    Inventors: Achim Gopferich, Jorg Tessmar, Michaela Schulz, Torsten Blunk, Antonios Mikos
  • Publication number: 20060141000
    Abstract: Polymeric materials are used to make a pliable, non-toxic, injectable porous template for vascular ingrowth. The pore size, usually between approximately 100 and 300 microns, allows vascular and connective tissue ingrowth throughout approximately 10 to 90% of the matrix following implantation, and the injection of cells uniformly throughout the implanted matrix without damage to the cells or patient. The introduced cells attach to the connective tissue within the matrix and are fed by the blood vessels. The preferred material for forming the matrix or support structure is a biocompatible synthetic polymer which degrades in a controlled manner by hydrolysis into harmless metabolites, for example, polyglycolic acid, polylactic acid, polyorthoester, polyanhydride, or copolymers thereof. The rate of tissue ingrowth increases as the porosity and/or the pore size of the implanted devices increases.
    Type: Application
    Filed: February 10, 2004
    Publication date: June 29, 2006
    Inventors: Antonios Mikos, Donald Ingber, Joseph Vacanti, Robert Langer
  • Publication number: 20060018949
    Abstract: Compositions for delivering a pharmaceutically active agent to the eye, and/or for treating an ophthalmic disorder, are based on a fumarate polymer, especially a poly(propylene fumarate) polymer.
    Type: Application
    Filed: March 14, 2005
    Publication date: January 26, 2006
    Applicant: Bausch & Lomb Incorporated
    Inventors: Daniel Ammon, Joseph Salamone, Hiroki Ueda, Seongbong Jo, Antonios Mikos