Patents by Inventor Antonis E. Koromilas

Antonis E. Koromilas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel anti-viral and anti-proliferative agents derived from STAT1 transcription factor
    Publication number: 20030049606
    Abstract: A STAT1 mutant which is unable to bind PKR is provided. The mutant is useful to enhance endogenous anti-viral and anti-proliferative activity in mammals.
    Type: Application
    Filed: January 25, 2002
    Publication date: March 13, 2003
    Inventors: Antonis E. Koromilas, Andrew Hoi-Tao Wong
  • Anti-tumor agent assay using PKR
    Patent number: 5670330
    Abstract: A method of screening human tissue for the presence of neoplastic cells, by determining the activity of PKR, P58 of anti-P58 in test cells being screened, and identifying candidate neoplastic cells on the basis of subnormal PKR, P58, or anti-P58 activity. The activities may be determined directly by measuring protein kinase activity or its equivalent, or measured indirectly, by detecting functional mutations in the various proteins. Also disclosed are assay kits for carrying out the screening method.
    Type: Grant
    Filed: October 25, 1993
    Date of Patent: September 23, 1997
    Assignees: McGill University, University of Washington
    Inventors: Nahum Sonenberg, Michael G. Katze, Sophie Roy, Antonis E. Koromilas, Glen H. Barber