Patents by Inventor Antony Bigot

Antony Bigot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 2-amino-4-heteroarylethyl-thiazoline derivatives as inhibitors of inducible no-synthase
    Publication number: 20030225140
    Abstract: The present invention relates to the use of 2-amino-4-heteroarylethyl-thiazoline derivatives of formula (I) 1
    Type: Application
    Filed: November 8, 2002
    Publication date: December 4, 2003
    Inventors: Eric Bacque, Antony Bigot, Jean-Christophe Carry, Serge Mignani
  • Epothilone derivatives and their synthesis and use
    Publication number: 20030203938
    Abstract: The invention relates to epothilone analog represented by the formula I 1
    Type: Application
    Filed: March 11, 2003
    Publication date: October 30, 2003
    Applicant: The Scripps Research Institute
    Inventors: Kyriacos Costa Nicolaou, Nigel Paul King, Maurice Raymond Verschoyle Finlay, Yun He, Frank Roschangar, Dionisios Vourloumis, Hans Vallberg, Antony Bigot
  • Use of 2-amino-thiazoline derivatives as inhibitors of inducible no-synthase
    Publication number: 20030166646
    Abstract: The present invention relates to the use of 2-amino-thiazoline derivatives of formula (I): 1
    Type: Application
    Filed: November 8, 2002
    Publication date: September 4, 2003
    Inventors: Antony Bigot, Jean-Christophe Carry, Serge Mignani
  • Use of 2-amino-4-pyridylmethyl-thiazoline derivatives as inhibitors of inducible NO-synthase
    Publication number: 20030153605
    Abstract: The present invention relates to the use of 2-amino-4-pyridylmethyl thiazoline derivatives of formula (I) 1
    Type: Application
    Filed: November 8, 2002
    Publication date: August 14, 2003
    Inventors: Eric Bacque, Antony Bigot, Jean-Christophe Carry, Serge Mignani, Baptiste Ronan, Michel Tabart
  • Epothilone derivatives and their synthesis and use
    Patent number: 6531497
    Abstract: The invention relates to epothilone analog represented by formula (I) wherein (i) R2 is absent or oxygen; “a” can be either a single or double bond; “b” can be either absent or a single bond; and “c” can be either absent or a single bond, with the proviso that if R2 is oxygen then “b” and “c” are both a single bond and “a” is a single bond; if R2 is absent then “b” and “c” are absent and “a” is a double bond; and if “a” is a double bond, then R2, “b” and “c” are absent; R3 is a radical selected from the group consisting of hydrogen; lower alkyl; —CH═CH2; —C≡CH; —CH2F; —CH2Cl; —CH2—OH; —CH2—O—(C1-C6-alkyl); and —CH2—S—(C1-C6-alkyl); R4 and R5 are independently selected from hydrogen, methyl or a protecting group; and R1 is as defined in the specification, or a salt of a compound of formu
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: March 11, 2003
    Assignee: The Scripps Research Institute
    Inventors: Kyriacos Costa Nicolaou, Nigel Paul King, Maruice Raymond Verschoyle Finlay, Yun He, Frank Roschangar, Dionisios Vourloumis, Hans Vallberg, Antony Bigot
  • 2-aminothiazoline derivatives and process for preparing the same
    Publication number: 20020198243
    Abstract: The present invention relates to a class of 2-aminothiazoline derivatives of formula I: 1
    Type: Application
    Filed: May 31, 2002
    Publication date: December 26, 2002
    Inventors: Jean-Christophe Carry, Dominique Damour, Claude Guyon, Serge Mignani, Antony Bigot, Eric Bacque, Michel Tabart
  • Use of 2-aminothiazoline derivatives as inhibitors of inducible NO-synthase
    Publication number: 20020187987
    Abstract: The present invention relates to the use of 2-aminothiazoline derivatives of formula I: 1
    Type: Application
    Filed: May 31, 2002
    Publication date: December 12, 2002
    Inventors: Jean-Christophe Carry, Dominique Damour, Claude Guyon, Serge Mignani, Antony Bigot, Eric Bacque, Michel Tabart
  • Use of 2-aminothiazoline derivatives as inhibitors of inducible no-synthase
    Patent number: 6451821
    Abstract: The present invention relates to the use of 2-aminothiazoline derivatives of formula: in which either R1 is a hydrogen atom or an alkyl radical and R2 is an alkyl, -alk—NH2, —CH2—R3, —CH2—S—R4 or phenyl radical substituted with a nitro or —NH— C (═NH) CH3 radical, or R1 is an alkyl radical and R2 is a hydrogen atom, R3 is a (3-6C) cycloalkyl, pyridyl, pyridyl N-oxide, thienyl, thiazolyl, imidazolyl, pyrazinyl, triazolyl or phenyl radical or a phenyl radical substituted with a nitro, hydroxy or carboxyl radical, R4 represents a pyridyl or pyridyl N-oxide radical, alk represents an alkylene radical, or pharmaceutically acceptable salts thereof, as inhibitors of inducible NO-synthase.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: September 17, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Jean-Christophe Carry, Dominique Damour, Claude Guyon, Serge Mignani, Antony Bigot, Eric Bacque, Michel Tabart
  • Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof
    Patent number: 6420566
    Abstract: The present invention relates to pharmaceutical compositions containing, as active principle, a 4,5-dihydro-1,3-thiazol-2-ylamine derivative of formula (I): in which R represents an -alk-S-alk-Ar radical, a phenyl radical or a phenyl radical substituted with alkoxy or halogen, or to one of the pharmaceutically acceptable salts thereof, to the novel derivatives of formula (I) and to their preparation.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: July 16, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Jean-Christophe Carry, Dominique Damour, Claude Guyon, Serge Mignani, Eric Bacque, Antony Bigot
  • Use of 2-aminothiazoline derivatives as inhibitors of inducible no-synthase
    Publication number: 20020022631
    Abstract: The present invention relates to the use of 2-aminothiazoline derivatives of formula: 1
    Type: Application
    Filed: June 8, 2001
    Publication date: February 21, 2002
    Inventors: Jean-Christophe Carry, Dominique Damour, Claude Guyon, Serge Mignani, Antony Bigot, Eric Bacque, Michel Tabart
  • Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof
    Publication number: 20020019427
    Abstract: The present invention relates to pharmaceutical compositions containing, as active principle, a 4,5-dihydro-1,3-thiazol-2-ylamine derivative of formula (I): 1
    Type: Application
    Filed: June 8, 2001
    Publication date: February 14, 2002
    Inventors: Jean-Christophe Carry, Dominique Damour, Claude Guyon, Serge Mignani, Eric Bacque, Antony Bigot