Patents by Inventor Antony Booth

Antony Booth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoassays and engineered proteins for monitoring antibody treatments to the immune checkpoint inhibitors PD1 and PD-L1
    Patent number: 11919938
    Abstract: Fusion proteins comprising an extracellular domain of PD1 (programmed cell death protein-1) protein and/or an extracellular domain of PD-L1 (programmed cell death-ligand 1 protein (CD274 or B7-H1)) protein. Portions of the extracellular domains are expressed in specific configurations and purified as protein and used in immunoassays to monitor the circulating levels of biotherapeutic antibodies to these proteins. Also described is a method of determining the amount of circulating levels of a biotherapeutic antibody in a biological sample obtained from a patient, wherein a patient has undergone at least one dose of immunotherapy.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: March 5, 2024
    Assignee: GRIFOLS DIAGNOSTIC SOLUTIONS INC.
    Inventors: Jody Berry, Elizabeth Antony Booth, Joyee Antony George, Elisabete Nascimento, Daniel Nagore Casas
  • IMMUNOASSAYS AND ENGINEERED PROTEINS FOR MONITORING ANTIBODY TREATMENTS TO THE IMMUNE CHECKPOINT INHIBITORS PD1 AND PD-L1
    Publication number: 20200299353
    Abstract: Fusion proteins comprising an extracellular domain of PD1 (programmed cell death protein-1) protein and/or an extracellular domain of PD-L1 (programmed cell death-ligand 1 protein (CD274 or B7-H1)) protein. Portions of the extracellular domains are expressed in specific configurations and purified as protein and used in immunoassays to monitor the circulating levels of biotherapeutic antibodies to these proteins. Also described is a method of determining the amount of circulating levels of a biotherapeutic antibody in a biological sample obtained from a patient, wherein a patient has undergone at least one dose of immunotherapy.
    Type: Application
    Filed: November 29, 2018
    Publication date: September 24, 2020
    Applicant: GRIFOLS DIAGNOSTIC SOLUTIONS INC.
    Inventors: JODY BERRY, ELIZABETH Antony BOOTH, JOYEE ANTONY GEORGE, ELISABETE NASCIMENTO, DANIEL NAGORE CASAS
  • Waveguide and method of manufacture
    Publication number: 20050073463
    Abstract: A hollow waveguide (1) has a wall (3) having plural pegs (16) thereon. The pegs (16) which project into the hollow interior of the waveguide (1) such that the waveguide (1) propagates electromagnetic waves only below a certain frequency. The surface of each of the pegs (16) is substantially free of discontinuity and concavities. The waveguide (1) may be manufactured by a moulding process.
    Type: Application
    Filed: November 25, 2002
    Publication date: April 7, 2005
    Inventors: Esen Bayar, Antony Booth