Patents by Inventor Antony J. Davies

Antony J. Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making a thrombin inhibitor
    Publication number: 20020103379
    Abstract: The invention is a process for preparing 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide which comprises coupling 1
    Type: Application
    Filed: December 6, 2001
    Publication date: August 1, 2002
    Inventors: Ulf H. Dolling, Ramon Alabaster, Michael S. Ashwood, Ian F. Cottrell, Cameron J. Cowden, Antony J. Davies, David Hands, Debra J. Wallace, Robert D. Wilson
  • Process for synthesizing carbapenem side chain intermediates
    Patent number: 6063931
    Abstract: A process of synthesizing a compound of the formula 1: ##STR1## is described. A compound of the formula 2: ##STR2## is reacted with diphenylphosphinic chloride to activate the carboxylic acid group, and then reacted with methanesulfonyl chloride to produce a compound of formula 4: ##STR3## Compound 4 is then reacted with a group II metal sulfide source in water to produce a compound of formula 1.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: May 16, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Karel M. J. Brands, John M. Williams, Ulf H. Dolling, Ronald B. Jobson, Antony J. Davies, Ian F. Cottrell, Mark Cameron, Michael S. Ashwood
  • Process for synthesizing carbapenem side chain intermediates
    Patent number: 6060607
    Abstract: A process of synthesizing a compound of the formula 1: ##STR1## is described. A compound of the formula 2: ##STR2## is reacted with diphenylphosphinic chloride to activate the carboxylic acid group, and then reacted with methanesulfonyl chloride to produce a compound of formula 4: ##STR3## Compound 4 is then reacted with a group II metal sulfide source in water to produce a compound of formula 1.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: May 9, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Karel M. J. Brands, John M. Williams, Ulf H. Dolling, Ronald B. Jobson, Antony J. Davies, Ian F. Cottrell, Mark Cameron, Michael S. Ashwood