Abstract: An apparatus for increasing the rate of expansion of tissue area and volume, either in vivo or in vitro, which comprises a tissue expansion device suitable for expansion of tissue and a controller connected to the device, wherein the controller causes the device to subject the tissue to stretching forces that alternatively increase and decrease to provide a series of stretch and relax phases during a period of tissue expansion without intervention of an operator.

Abstract: Disclosed are various devices and methods for delivering bronchial isolation devices into the lung of a patient. In accordance with one aspect of the invention, there is disclosed an apparatus for deploying a bronchial device in a bronchial passageway in a lung of a patient. The apparatus comprises a flexible shaft having an inner lumen and a distal end adapted to engage the bronchial isolation device. The apparatus further comprises a wire slidably disposed in the inner lumen and a housing movably coupled to the distal end of the shaft and configured to receive the bronchial device. The wire is connected to the housing to produce relative movement between the housing and the shaft to deploy the bronchial device from the housing.

Abstract: Disclosed is a flow control device for a bronchial passageway. The device can includes a valve member that regulates fluid flow through the flow control device, a frame coupled to the valve member, and a membrane attached to the frame. At least a portion of the flow control device forms a seal with the interior wall of the bronchial passageway when the flow control device is implanted in the bronchial passageway. The membrane forms a fluid pathway from the seal into the valve member to direct fluid flowing through the bronchial passageway into the valve member.

Abstract: An implantable flow control element is provided which prevents air from entering an isolated portion of a patient's lung. The element may permit air to escape from the isolated portion so that the element acts like a valve. Systems for implanting pulmonary devices are also provided.

Abstract: A method of increasing the rate of expansion of tissue area and volume, either in vivo or in vitro, which comprises preparing a tissue for expansion and subjecting the tissue to stretching forces, wherein the stretching forces are alternatively increased and decreased to provide alternating periods of stretch and relax cycles.

Abstract: Disclosed are methods and devices for regulating fluid flow in one or more lung regions that are supplied fluid through one or more collateral pathways. An identified region of the lung is targeted for volume reduction or collapse. The targeted lung region is then bronchially isolated to inhibit air from flowing into the targeted lung region through bronchial pathways that directly feed air to the targeted lung region. If the targeted lung region does not collapse after bronchially isolating the targeted lung region, then it is possible that a collateral pathway is feeding air to the targeted lung region, thereby preventing the targeted lung region from collapsing. In such a case, the collateral pathway is identified and air flow into the targeted lung region via the collateral pathway is reduced or eliminated.

Abstract: Disclosed is a pump device that can be implanted into a body passageway, such as into a bronchial passageway. The pump device can be used to pump fluid through the body passageway, such as in order to assist the expiration of fluid from a region of the lung that fluidly communicates with the body passageway. The pump device includes a housing that defines an internal chamber, wherein fluid can flow through the chamber. The housing is dimensioned for insertion into a bronchial passageway. The pump device also includes a fluid propulsion mechanism in fluid communication with the chamber. The fluid propulsion mechanism is positioned to propel fluid through the chamber so as to pump fluid through the bronchial passageway in a desired direction.

Abstract: Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. An identified region of the lung is targeted for treatment, such as to modify the flow to the targeted lung region or to achieve volume reduction or collapse of the targeted lung region. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. The bronchial isolation of the targeted lung region is accomplished by implanting a flow control device into a bronchial passageway that feeds air to a targeted lung region.

Abstract: A method of increasing the rate of expansion of tissue area and volume, either in vivo or in vitro, which comprises preparing a tissue for expansion and subjecting the tissue to stretching forces, wherein the stretching forces are alternatively increased and decreased to provide alternating periods of stretch and relax cycles.

Abstract: An implantable flow control element is provided which prevents air from entering an isolated portion of a patient's lung. The element may permit air to escape from the isolated portion so that the element acts like a valve. Systems for implanting pulmonary devices are also provided.

Abstract: A trash collection and compacting apparatus primarily intended for use onboard an aircraft comprising a stationary compactor unit and interrelated movable trolley unit, the trolley unit having a plurality of separate trash collection chambers into which trash is deposited and compacted. The trolley unit includes wheels for moving the trolley through an aircraft for the collection of trash, and support rails for supporting the trolley unit on the compactor unit for the direct compaction of trash in the trolley. The compactor unit includes a compaction ram mounted on a carriage assembly for movement into discrete positions overlying each collection chamber of the trolley unit, and supports the trolley so that compaction forces are not transmitted to the aircraft.

Abstract: A trash collection and compacting apparatus primarily intended for use onboard an aircraft comprising a stationary compactor unit and interrelated movable wheeled trolley unit, the trolley unit having a plurality of separate trash collection chambers into which trash is deposited and compacted and support rails for supporting the trolley unit on the compactor unit for the direct compaction of trash in the trolley. The trolley unit also has separable sides to facilitate removal of compacted trash, and multiple fail safe locks and latches to ensure that the sides are not inadvertently separated during trash collection and compaction. Fire doors are provided to close the chambers, and removable trash bins are disposed in each trash chamber to facilitate handling of compacted trash, the bins having separable sides for emptying the compacted trash therefrom.