Patents by Inventor Antti Haapalinna

Antti Haapalinna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polycyclic compounds as potent alpha2-adrenoceptor antagonists
    Patent number: 7592350
    Abstract: A compound of formula I, wherein X, Z, R1 to R10, R15, R16, m, n, r and t are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds of formula I can be used for the treatment of diseases or conditions where antagonists of alpha-2 adrenoceptors are indicated to be effective.
    Type: Grant
    Filed: April 3, 2003
    Date of Patent: September 22, 2009
    Assignee: Orion Corporation
    Inventors: David Din Belle, Reija Jokela, Arto Tolvanen, Antti Haapalinna, Arto Karjalainen, Jukka Sallinen, Jari Ratilainen
  • Treatment of Epilepsy
    Publication number: 20080207719
    Abstract: The disclosure relates to a method for the inhibition of the development of epilepsy with an alpha2-adrenoceptor antagonist or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: April 8, 2004
    Publication date: August 28, 2008
    Applicant: ORION CORPORATION
    Inventors: Antti Haapalinna, Asla Pitkanen
  • Polycyclic compounds as potent alpha2-adrenoceptor antagonists
    Publication number: 20070293527
    Abstract: A compound of formula 1, wherein X, Z, R1 to R10, R15, R16, m, n, r and t are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds of formula I can be used for the treatment of diseases or conditions where antagonists of alpha-2 adrenoceptors are indicated to be effective.
    Type: Application
    Filed: April 3, 2003
    Publication date: December 20, 2007
    Inventors: David Din Belle, Reija Jokela, Arto Tolvanen, Antti Haapalinna, Arto Karjalainen, Jukka Sallinen, Jari Ratilainen
  • Polycyclic compounds as potent alpha2-adrenoceptor antagonists
    Publication number: 20060094740
    Abstract: A compound of formula 1, wherein X, Z, R1 to R10, R15, R16, m, n, r and t are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds of formula I can be used for the treatment of diseases or conditions where antagonists of alpha-2 adrenoceptors are indicated to be effective.
    Type: Application
    Filed: April 3, 2003
    Publication date: May 4, 2006
    Inventors: David Din Belle, Reija Jokela, Arto Tolvanen, Antti Haapalinna, Arto Karjalainen, Jukka Sallinen, Jari Ratilainen
  • Treatment of dependence and dependence related withdrawal symptoms
    Publication number: 20060058364
    Abstract: A method for treatment of dependence and dependence related withdrawal symptoms caused by the discontinuation of subacute or chronic use of psychostimulant agents, to ease a patient's withdrawal from the psychostimulants with an alpha2-adrenoceptor antagonist or a pharmaceutically acceptable ester or salt thereof.
    Type: Application
    Filed: March 28, 2003
    Publication date: March 16, 2006
    Inventors: Antti Haapalinna, Timo Viitamaa, Raimo Virtanen
  • Prevention of development of dyskinesias
    Publication number: 20040039041
    Abstract: The present invention relates to the prevention of the development of sensitization caused by chronic use of dopaminergic agents using an alfa2-adrenoceptor antagonist or a pharmaceutically acceptable ester or salt thereof.
    Type: Application
    Filed: September 9, 2003
    Publication date: February 26, 2004
    Inventors: Antti Haapalinna, Juuso Juhila, Jouni Sirvio
  • Derivatives of quinoline as alpha-2 antagonists
    Publication number: 20030225078
    Abstract: A compound of formula I, 1
    Type: Application
    Filed: April 16, 2003
    Publication date: December 4, 2003
    Applicants: Orion Corporation, Oy Juvantia Pharma Ltd.
    Inventors: Siegfried Wurster, Mia Engstrom, Juha-Matti Savola, Iisa Hoglund, Jukka Sallinen, Antti Haapalinna, Andrei Yurievitch Tauber, Anna-Marja Katariina Hoffren, Harri Elias Salo
  • Dervatives of quinoline as alpha-2 antagonists
    Patent number: 6593324
    Abstract: A compound of formula I, wherein A, Ra, Rb, R1 to R5, m and t are as defined as disclosed, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds I can be used for the treatment of diseases or conditions where alpha-2 antagonists are indicated to be effective.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: July 15, 2003
    Assignees: Orion Corporation, Oy Juvantia Pharma Ltd.
    Inventors: Siegfried Wurster, Mia Engström, Juha-Matti Savola, Iisa Höglund, Jukka Sallinen, Antti Haapalinna, Andrei Yurievitch Tauber, Anna-Marja Katariina Hoffrén, Harri Elias Salo
  • Use of 3-(1H-imidazol-4-ylmethyl)-indan-5-ol in the manufacture of a medicament for intraspinal, intrathecal or epidural administration
    Patent number: 6495584
    Abstract: The present invention relates to a method for obtaining analgesia by administering 3-(1H-imidazol-4-ylmethyl)-indan-5-ol, its enetiomer or pharmaceutically acceptable ester or salt thereof to a mammal intraspinally, 3-(1H-imidazol-4-ylmethyl)-indan-5-ol, its enantiomer or a pharmaceutically acceptable ester or salt thereof can be administered intraspinally to a mammal obtaining analgesia without side-effects, such as sedation. The present invention also relates to a method for using the drug as an adjunct to anaesthesia by administering it intraspinally.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: December 17, 2002
    Assignee: Orion Corporation
    Inventors: Antti Haapalinna, Jyrki Lehtimäki, Tiina Leino, Timo Viitamaa, Raimo Virtanen
  • Method for treating sexual disorders
    Publication number: 20020132858
    Abstract: A method of treating sexual disorders in a mammal by administering to the mammal an effective amount of 1,7,7-trimethylbicyclo[2.2.
    Type: Application
    Filed: May 15, 2002
    Publication date: September 19, 2002
    Applicant: Orion Corporation
    Inventors: Outi Maki-Ikola, Antti Haapalinna
  • Treatment method
    Publication number: 20020115704
    Abstract: A method for the treatment of female sexual dysfunction and enhancement of normal sexual function in females with an alpha2-adrenoceptor antagonist or a pharmaceutically acceptable ester or salt thereof.
    Type: Application
    Filed: December 14, 2001
    Publication date: August 22, 2002
    Inventors: Ilkka Linnankoski, Antti Pertovaara, Antti Haapalinna, Raimo Virtanen
  • Prevention of development of dyskinesias
    Publication number: 20020115703
    Abstract: The present invention relates to, among other things, a method for prevention or inhibition of the development of sensitization caused by the chronic use of dopaminergic agents with an alpha2-adrenoceptor antagonist or a pharmaceutically acceptable ester or salt thereof.
    Type: Application
    Filed: November 14, 2001
    Publication date: August 22, 2002
    Inventors: Antti Haapalinna, Juuso Juhila, Jouni Sirvio
  • Method for treating sexual disorders
    Publication number: 20020099098
    Abstract: A method of treating sexual disorders in a mammal by administering to the mammal an effective amount of 1,7,7-trimethylbicyclo[2.2.
    Type: Application
    Filed: January 22, 2001
    Publication date: July 25, 2002
    Inventors: Outi Maki-Ikola, Antti Haapalinna
  • Imidazole derivatives
    Patent number: 6388090
    Abstract: An imidazole derivative of formula (I) or a pharmaceutically acceptable salt or derivative thereof. The compounds of formula I exhibit affinity for alpha2 adrenoceptors.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: May 14, 2002
    Assignee: Orion Corporation
    Inventors: Paavo Huhtala, Arto Karjalainen, Antti Haapalinna, Jyrki Lehtimäki, Arja Karjalainen, Raimo Virtanen
  • Polycyclic indanylimidazoles with alpha2 adrenergic activity
    Patent number: 6362211
    Abstract: A compound of formula I wherein R1 to R3, —A—, m and t are as defined in claim 1, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha2 adrenergic agent.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: March 26, 2002
    Assignee: Orion Corporation
    Inventors: Jari Ratilainen, Paavo Huhtala, Arto Karjalainen, Arja Karjalainen, Antti Haapalinna, Raimo Virtanen, Jyrki Lehtimäki
  • New polycyclic indanylimidazoles with alpha2 adrenergic activity
    Publication number: 20020013356
    Abstract: A compound of formula I 1
    Type: Application
    Filed: May 7, 2001
    Publication date: January 31, 2002
    Inventors: Jari Ratilainen, Paavo Huhtala, Arto Karjalainen, Arja Karjalainen, Antti Haapalinna, Raimo Virtanen, Jyrki Lehtimaki
  • Imidazole derivatives
    Publication number: 20010056109
    Abstract: An imidazole derivative of formula (I) 1
    Type: Application
    Filed: January 12, 2001
    Publication date: December 27, 2001
    Inventors: Paavo Huhtala, Arto Karjalainen, Antti Haapalinna, Jyrki Lehtimaki, Arja Karjalainen, Raimo Virtanen
  • Derivatives of quinoline as alpha-2 antagonists
    Publication number: 20010046991
    Abstract: A compound of formula I, 1
    Type: Application
    Filed: February 28, 2001
    Publication date: November 29, 2001
    Inventors: Siegfried Wurster, Mia Engstrom, Juha-Matti Savola, Iisa Hoglund, Jukka Sallinen, Antti Haapalinna, Andrei Yurievitch Tauber, Anna-Marja Katariina Hoffren, Harri Elias Salo
  • Method for the treatment of mental illness in mammals and a composition therefor
    Patent number: 5902807
    Abstract: The invention relates to a method for treating a mammal suffering from mental illness induced by propagation of stress, said method comprising the step of removing or diminishing the tone of the endogenous alpha-2C-adrenoceptors in the central nervous system of said mammal. The invention relates further to pharmaceutical compositions useful for said treatment.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: May 11, 1999
    Assignee: Antti Haapalinna
    Inventors: Antti Haapalinna, Timo Viitamaa, Jukka Sallinen, Mika Scheinin, Juha-Matti Savola