Patents by Inventor Anu Mahadevan

Anu Mahadevan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3?,5?-dimethoxybenzoyl-3?-amino-3?-deoxy adenosine-5?-triphosphates and pharmaceutical uses thereof
    Patent number: 11440935
    Abstract: Provided are compounds compound according to Formula (I), or a pharmaceutically acceptable salt, solvate, coordination complex or prodrug thereof: wherein, R1 and R2 are independently selected from (C1-C6) alkyl. The compounds have P2X3 receptor or P2X2/3 receptor antagonist activity and are useful for the treatment of diseases and disorders characterized by activation of those receptors.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: September 13, 2022
    Assignee: MERCK PATENT GMBH
    Inventors: Amir Pelleg, Anu Mahadevan, Jie Li, Cynthia Morency
  • 3'',5''-DIMETHOXYBENZOYL-3'-AMINO-3'-DEOXYADENOSINE-5'-TRIPHOSPHATES AND PHARMACEUTICAL USES THEREOF
    Publication number: 20210054015
    Abstract: Provided are compounds compound according to Formula (I), or a pharmaceutically acceptable salt, solvate, coordination complex or prodrug thereof: wherein, R1 and R2 are independently selected from (C1-C6) alkyl. The compounds have P2X3 receptor or P2X2/3 receptor antagonist activity and are useful for the treatment of diseases and disorders characterized by activation of those receptors.
    Type: Application
    Filed: March 14, 2019
    Publication date: February 25, 2021
    Inventors: Amir PELLEG, Anu MAHADEVAN, Jie LI, Cynthia MORENCY
  • Inflammation therapy
    Patent number: 9763894
    Abstract: A method is provided for treating a patient in need of therapy for central nervous system inflammation comprising administering to that patient a therapeutically effective amount of a cannabinoid agonist having efficacy at the CB2 receptor but having substantially no efficacy at the CB1 receptor at that amount.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: September 19, 2017
    Assignees: Virginia Commonwealth University, Organix, Inc., Temple University
    Inventors: Billy R. Martin, Mohamad Imad Damaj, Martin W. Adler, Ronald F. Tuma, Ming Zhang, Anu Mahadevan, Raj K. Razdan
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20150299225
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: November 14, 2014
    Publication date: October 22, 2015
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • Compounds for modulating TRPV3 function
    Patent number: 8916550
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: December 23, 2014
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20140155417
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: August 30, 2013
    Publication date: June 5, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis Underwood, Manfred Weigele, Xiaoguang Zhen
  • Substituted pyrimido 4.5-d pyrimidin-4-one compounds for modulating TRPV3 function
    Patent number: 8552009
    Abstract: The present application relates to compounds of Formula I as defined herein, and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: October 8, 2013
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy S. Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • Compounds for Modulating TRPV3 Function
    Publication number: 20110144135
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 16, 2011
    Applicant: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds for modulating TRPV3 function
    Patent number: 7803790
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: September 28, 2010
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds for Modulating TRPV3 Function
    Publication number: 20100152209
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: November 3, 2006
    Publication date: June 17, 2010
    Applicant: Hydra Biosciences Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Inflammation Therapy
    Publication number: 20080139635
    Abstract: A method is provided for treating a patient in need of therapy for central nervous system inflammation comprising administering to that patient a therapeutically effective amount of a cannabinoid agonist having efficacy at the CB2 receptor but having substantially no efficacy at the CB1 receptor at that amount.
    Type: Application
    Filed: December 5, 2007
    Publication date: June 12, 2008
    Inventors: Billy R. Martin, Mohamad Imad Damaj, Martin W. Adler, Ronald F. Tuma, Ming Zhang, Anu Mahadevan, Raj K Razdan
  • Water Soluble Cannabinoids
    Publication number: 20080064679
    Abstract: Water-soluble cannabinoid compounds that are agonists of CB1 and CB2 cannabinoid receptors are provided. The compounds are made water-soluble by derivatization of the alkyl side chain and/or the phenolic hydroxyl group of tetrahydrocannabinol. The water-soluble cannabinoids are useful for the treatment of appetite loss, pain, multiple sclerosis, nausea and vomiting, and epilepsy.
    Type: Application
    Filed: June 23, 2005
    Publication date: March 13, 2008
    Inventors: Billy R. Martin, Raj K. Razdan, Anu Mahadevan
  • Anti-spasticity of an eicosanoid analog
    Patent number: 6800770
    Abstract: The invention compounds and methods for the treatment of motor disorders. In particular, the invention provides eicosanoid analogs which are effective in ameliorating motor disorders such as spasticity caused by multiple sclerosis (MS).
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: October 5, 2004
    Assignee: Virginia Commonwealth University
    Inventors: Billy Martin, Raj K. Razdan, Anu Mahadevan, David Baker
  • Anti-spasticity of an eicosanoid analog
    Publication number: 20040002541
    Abstract: The invention compounds and methods for the treatment of motor disorders. In particular, the invention provides eicosanoid analogs which are effective in ameliorating motor disorders such as spasticity caused by multiple sclerosis (MS).
    Type: Application
    Filed: January 17, 2003
    Publication date: January 1, 2004
    Inventors: Billy Martin, Raj K. Razdan, Anu Mahadevan, David Baker
  • Pyrazole cannabinoid agonist and antagonists
    Patent number: 6509367
    Abstract: Disclosed are pyrazole derivatives of formula I: Where R1, R2, R3, and R4 are defined as in the specification described. These compounds are antagonists of the brain cannabinoid (CB-1) receptors and could be used as active gradients in pharmaceutical preparations to block or inhibit cannabinoid receptors in mammals.
    Type: Grant
    Filed: September 22, 2001
    Date of Patent: January 21, 2003
    Assignees: Virginia Commonwealth University, Organix, Inc.
    Inventors: Billy R. Martin, Raj K. Razdan, Anu Mahadevan