Patents by Inventor Anu Puri

Anu Puri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Binary lipid bilayer-containing vesicles comprising embedded cytotoxic agents and methods of making and using the same
    Patent number: 12178907
    Abstract: Embodiments of vesicles comprising embedded cytotoxic agents are disclosed, as well as methods of making and using the vesicles. Pharmaceutical compositions including the vesicles also are disclosed. The vesicles include a binary lipid bilayer surrounding a cavity, wherein the vesicle binary lipid bilayer includes (i) a non-bilayer forming lipid (or combination of non-bilayer forming lipids) and a PEGylated lipid; and (i) a cytotoxic agent embedded within the vesicle wall.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: December 31, 2024
    Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Anu Puri, Mathias Viard
  • BINARY LIPID BILAYER-CONTAINING VESICLES COMPRISING EMBEDDED CYTOTOXIC AGENTS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20210236424
    Abstract: Embodiments of vesicles comprising embedded cytotoxic agents are disclosed, as well as methods of making and using the vesicles. Pharmaceutical compositions including the vesicles also are disclosed. The vesicles include a binary lipid bilayer surrounding a cavity, wherein the vesicle binary lipid bilayer includes (i) a non-bilayer forming lipid (or combination of non-bilayer forming lipids) and a PEGylated lipid; and (i) a cytotoxic agent embedded within the vesicle wall.
    Type: Application
    Filed: July 11, 2019
    Publication date: August 5, 2021
    Applicant: The USA, as represented by the Secretary, Department of Health and Human Services
    Inventors: Anu Puri, Mathias Viard
  • Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery
    Patent number: 10117942
    Abstract: Embodiments of photoactivatable, lipid-based nanoparticles are disclosed, as well as methods of making and using the nanoparticles. Pharmaceutical compositions including the nanoparticles also are disclosed. The lipid-based nanoparticles include a vesicle wall surrounding a cavity, wherein the vesicle wall includes (i) a lipid bilayer comprising 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC), dipalmitoylphosphatidylcholine (DPPC), and (ii) 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) within the lipid bilayer. The nanoparticles may further include an agent within the cavity.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: November 6, 2018
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Baylor College of Medicine
    Inventors: Anu Puri, Robert P. Blumenthal, Amit Joshi, Darayash B. Tata, Mathias Viard
  • PHOTOACTIVATABLE LIPID-BASED NANOPARTICLES AS VEHICLES FOR DUAL AGENT DELIVERY
    Publication number: 20160136289
    Abstract: Embodiments of photoactivatable, lipid-based nanoparticles are disclosed, as well as methods of making and using the nanoparticles. Pharmaceutical compositions including the nanoparticles also are disclosed. The lipid-based nanoparticles include a vesicle wall surrounding a cavity, wherein the vesicle wall includes (i) a lipid bilayer comprising 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC), dipalmitoylphosphatidylcholine (DPPC), and (ii) 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) within the lipid bilayer. The nanoparticles may further include an agent within the cavity.
    Type: Application
    Filed: July 9, 2014
    Publication date: May 19, 2016
    Applicants: The USA, as represented by the Secretary, Department of Health and Human Services, Baylor College of Medicine
    Inventors: Anu Puri, Robert P. Blumenthal, Amit Joshi, Darayash B. Tata