Abstract: Systems and methods for control of a medical data processing system are provided. Some embodiments are particularly directed to presenting a user interface for control of an IVUS imaging system. In one embodiment, a method comprises: presenting a set of mode options to a user at a user display device; receiving a mode selection selected by the user; determining a set of operating parameters based on the mode selection; receiving, by a medical processing system, a first set of medical sensing data; and processing, by the medical processing system, the first set of medical sensing data according to the operating parameters. The determining may be further based on at least one of a previous mode selection, a user preference, an operative course of a medical procedure, patient information, the first set of medical sensing data, a second set of medical sensing data, a status indicator, and a sensing device identifier.

Abstract: The invention is a system comprising an intravascular imaging probe having expanded imaging capabilities and a processor for processing the image data and causing relevant information, such as flow, to be displayed. The system is configured to cause image data to be processed and reconfigured in a user friendly format, e.g., color-coded, to provide details of flow, including the automated, or semi-automated, detection of endoleaks at or near a placement site of a stent graft within a lumen associated with an EVAR or TEVAR procedure. The system is further configured to provide identification of the type of endoleak present.

Abstract: The invention provides co-registration systems and methods for detecting endoleaks associated with aneurysm repair. The system includes an imaging device having expanded imaging capabilities and configured to capture and provide image data and flow visualization of a vessel based on the image data. The system further includes one or more sensors for capturing functional parameters of the vessel, such as flow or pressure. The system further includes an external imaging modality for capturing external image data of the vessel, such as, for example, a radiological image. The co-registration system is configured to co-register sets of data captured by a plurality of intra- and extraluminal modalities and provide a composite map (3- or multi-dimensional) of the vessel including automatically detected areas of interest, particularly during an EVAR or TEVAR procedure.

Abstract: A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.

Abstract: The invention generally relates to systems and methods for producing intravascular images. In certain embodiments, systems and methods of the invention involve causing transducers of an intravascular ultrasound device to generate a plurality of different types of data, each type of data being based on a different manner of operation of the transducers. The systems and methods of the invention additionally involve adjusting the manner of operation of the transducers for one of the types of data to thereby adjust an acquisition frame rate of the one type of data to an adjusted acquisition frame rate. The one type of data at the adjusted acquisition frame rate is then received and an intravascular image that includes the one type of data at the adjusted acquisition frame rate is displayed.

Abstract: The invention generally relates to systems and methods for producing composite intravascular images of multiple data types. In certain embodiments, systems and methods of the invention involve causing transducers of an intravascular ultrasound device to generate a plurality of different types of data, each type of data being based on a different manner of operation of the transducers. The manner of operation of the transducers is adjusted for one of the types of data to thereby cause the transducers to generate modified data for the one type of data. The modified data is received and an intravascular image is displayed that includes the modified data.

Abstract: Disclosed herein is a system and method for characterizing adventitial tissue. In one aspect, a system and method is disclosed that characterizes tissue types within the adventitial tissue including nerve bundles and blood vessels. In a further aspect, the adventitia is imaged and characterized to provide guidance for crossing lesions within an occluded vessel.

Abstract: Systems and methods for tissue characterization using multiple independent pattern recognition models are provided. Some embodiments are particularly directed to analyzing medical imaging data. In one embodiment, a method includes receiving a set of medical imaging data and receiving a set of independent tissue characterization models. Each of the set of independent tissue characterization models is applied to the set of medical imaging data in order to obtain a plurality of interim classification results. An arbitration of the plurality of interim classification results is performed to determine a constituent tissue for the set of medical imaging data. The determined constituent tissue may be displayed in combination with a graphical representation of the set of medical imaging data. Each of the set of independent tissue characterization models may be applied to the set of medical imaging data in parallel.

Abstract: A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto—e.g., IVUS console, transducer, etc.). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e.g., a blood vessel, etc.). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure.

Abstract: Systems and methods for control of a medical data processing system are provided. Some embodiments are particularly directed to presenting a user interface for control of an IVUS imaging system. In one embodiment, a method comprises: presenting a set of mode options to a user at a user display device; receiving a mode selection selected by the user; determining a set of operating parameters based on the mode selection; receiving, by a medical processing system, a first set of medical sensing data; and processing, by the medical processing system, the first set of medical sensing data according to the operating parameters. The determining may be further based on at least one of a previous mode selection, a user preference, an operative course of a medical procedure, patient information, the first set of medical sensing data, a second set of medical sensing data, a status indicator, and a sensing device identifier.

Abstract: A method for imaging a volume within a patient volume is provided. The method includes generating a first signal and a second signal, directing the first signal and the second signal to a spot in the patient volume; receiving a first response signal and a second response signal from the spot in the patient volume; providing a first image from of the patient volume using the first response signal; providing a second image from the patient volume using the second response signal; and combining the first image and the second image to form a composite image. The method includes receiving multiple images at multiple frequency ranges; selecting a region of interest including the plurality of images; selecting multiple border lines separating the region of interest into multiple sub-regions; selecting data from an image in a sub-region; and forming an image in the region of interest.

Abstract: Disclosed herein is a system for ablating and characterizing tissue. The system comprises an ablation element configured to emit ablative energy toward a tissue of interest, an imaging apparatus configured to emit energy and collect imaging data including reflected signals from the tissue of interest, and a characterization application. The characterization application comprises a signal analyzer for analyzing the imaging data and determining one or more signal properties from the reflected signals, and a correlation processor configured to associate the one or more signal properties to pre-determined tissue signal properties of different tissue components through a pattern recognition technique. The pre-determined tissue signal properties are embodied in a database, and the correlation processor is configured to identify a tissue component and an ablation level of the tissue of interest based on the pattern recognition technique.

Abstract: Disclosed herein is a non-invasive system for determining tissue composition. The system comprises an imaging system with a non-invasive probe, a signal analyzer, and a correlation processor. The probe includes active imaging components for emitting energy and collecting imaging data including reflected signals from an object of interest. The signal analyzer analyzes the imaging data and determines one or more signal properties from the reflected signals. The correlation processor then associates the one or more signal properties to pre-determined tissue signal properties of different tissue components through a pattern recognition technique wherein the pre-determined tissue signal properties are embodied in a database, and identifies a tissue component of the object based on the pattern recognition technique.

Abstract: Systems and methods for aiding users in viewing, assessing and analyzing images, especially images of lumens and medical devices contained within the lumens. Systems and methods for interacting with images of lumens and medical devices, for example through a graphical user interface.

Abstract: This invention relates generally to methods and systems for removing an artifact within an image. Typically, the artifact is a guidewire artifact. In one aspect, at least two images of an imaging surface are acquired. Each acquired image comprises a set of data. A guidewire artifact is detected in one of the at least two images. The guidewire artifact is replaced with data representing the imaging surface obtained from another one of the at least two images. In certain embodiments, the at least two images are of the same imaging surface having a guidewire or object causing the artifact moved to a different position.

Abstract: A system and method are provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. In one embodiment, the computing device includes a plurality of applications operating thereon that are used to (I) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e., another IVUS image), (iii) identify a border on the second IVUS image, and (iv) adjust the border on the second IVUS image in accordance with at least one factor.

Abstract: A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter and/or substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. The backscattered ultrasound data is used, together with an algorithm, to estimate at least one transfer function. The transfer function(s) can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). The response data and histology data are then used to characterize at least a portion of the vascular tissue (e.g., identify tissue type, etc.). In some embodiments, the backscattered data is acquired during a cyclical portion of the heartbeat data so that the blood vessel can be analyzed or imaged as if it were standing still, or not expanding and relaxing.

Abstract: A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer.

Abstract: A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image.

Abstract: A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter and/or substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. In one embodiment, a computing device and catheter acquire RF backscattered data from a vascular structure. The backscattered ultrasound data is then used to estimate at least one transfer function. The transfer function(s) can then be used to calculate response data for the vascular tissue. Another embodiment includes an IVUS console connected to a catheter and a computing device that acquires RF backscattered data from a vascular structure. Based on the backscattered data, the computing device estimates the catheter's transfer function and to calculate response data for the vascular tissue. The response data and histology data are then used to characterize at least a portion of the vascular tissue.