Abstract: A user uploads date sets through a client to a database. The data sets are provisioned in the database for in-database searching. The data sets are evaluated and classifications for the columns of the tables that include the data set are detected. Columns content may be classified into different analysis types, aggregation types, formats, categories, hierarchies, etc. Metadata is generated based on the evaluation of the data sets. A schema is used to store the metadata that describes the detected classification of the columns. The schema is stored in the database and is used when a search in the database is performed.

Abstract: A method, implemented at least in part by a computing device, for software upgrade analysis includes receiving a selection of at least one object class of a plurality of available object classes. One or more application programming interface (API) calls may be retrieved from a plurality of API calls based on the received selection. A test definition may be generated based at least in part on the one or more API calls. A first test may be executed by using the one or more API calls in the test definition within a software environment. The first test is run on the software environment prior to upgrading the environment. Subsequent to upgrading the environment, a second test is executed by using the one or more API calls within the upgraded software environment. A software upgrade report is generated based on a comparison of test results from the first and second tests.

Abstract: A method, implemented at least in part by a computing device, for software upgrade analysis includes receiving a selection of at least one object class of a plurality of available object classes. One or more application programming interface (API) calls may be retrieved from a plurality of API calls based on the received selection. A test definition may be generated based at least in part on the one or more API calls. A first test may be executed by using the one or more API calls in the test definition within a software environment. The first test is run on the software environment prior to upgrading the environment. Subsequent to upgrading the environment, a second test is executed by using the one or more API calls within the upgraded software environment. A software upgrade report is generated based on a comparison of test results from the first and second tests.

Abstract: A user uploads date sets through a client to a database. The data sets are provisioned in the database for in-database searching. The data sets are evaluated and classifications for the columns of the tables that include the data set are detected. Columns content may be classified into different analysis types, aggregation types, formats, categories, hierarchies, etc. Metadata is generated based on the evaluation of the data sets. A schema is used to store the metadata that describes the detected classification of the columns. The schema is stored in the database and is used when a search in the database is performed.

Abstract: The present invention relates to processes for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate.

Abstract: The invention provides an Olanzapine pseudopolymoph Form E. The invention provides methods of preparing polymorphic Olanzapine Form E employing rapid crystallization and seeding. The invention provides methods of preparing anhydrous Olanzapine Form I from the Olanzapine Form E by step-wise drying.

Abstract: The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate.

Abstract: The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate.

Abstract: The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate.

Abstract: This invention provides a process of preparation of novel polymorphic hemifumarate salts of 8-chloro-6,11-dihyfro-11-(4-piperidylidene)-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine, hereinafter called “desloratadine”. These polymorphic salt forms show much higher solubility in water and also in protic organic solvents compare to the parent desloratadine. The process of preparing the polymorphic forms comprising: a) mixing the ethanolic solution of desloratadine and fumaric acid at a temperature of from about 55° C. to 70° C., and stirring for 30 to 45 minutes after mixing, and thereafter filtering the solid thereby prepared in hot condition; to yield the polymorphic form 2 having a DSC of 232° C.±2° C.; or b) mixing the ethanolic solution of desloratadine and fumaric acid at a temperature of form about 15° C. room temperature (25° C.) and stirring at this temperature for 30 to 45 minutes, then filtering at room temperature; to yield the polymorphic form 1 having a DSC of 224° C.±2° C.

Abstract: This invention provides a process of preparation of novel polymorphic hemifumarate salts of 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine, hereinafter called “desloratadine”. These polymorphic salt forms show much higher solubility in water and also in protic organic solvents compare to the parent desloratadine.

Abstract: A process for preparing 5-methylisoxazole-4-carboxylic-(4′-trifluoromethyl)-anilide comprising: (a) reacting ethylacetoacetate, triethylorthoformate, and acetic anhydride at a temperature of from about 75° C. to about 150° C., to form ethyl ethoxymethyleneacetoacetic ester; (b) combining the ethyl ethoxymethyleneacetoacetic ester with sodium acetate or a salt of trifluoroacetic acid in the presence of hydroxylamine sulfate at a temperature of from about −20° C. to 10° C., to form ethyl-5-methylisoxazole-4-carboxylate; (c) reacting the ethyl-5-methylisoxazole-4-carboxylate with a strong acid to form 5-methylisoxazole-4-carboxylic acid; (d) reacting the crystallized 5-methylisoxazole-4-carboxylic acid with thionyl chloride to form 5-methylisoxazole-4-carbonyl chloride; and (e) reacting the 5-methylisoxazole-4-carbonyl chloride with trifluoromethyl aniline and an amine base at a temperature of from about 0° C. to about 50° C.