Abstract: A descriptor of a dynamically materialized view is stored. The descriptor includes a query to select a subset of cells from a data sheet, and a result of executing the query. In response to an update directed to the data sheet, the result stored in the descriptor is modified based on re-executing the query, and a notification is transmitted to an execution platform at which an application whose output depends on the dynamically materialized view runs.

Abstract: In response to a determination that a first logical table is to be created in a data sheet, a respective row identifier is generated and stored for individual rows of the first logical table. To indicate a relationship between a particular cell of another logical table and a particular row of the first logical table, the row identifier of the particular row is stored. After a modification of a value stored in the particular row, the row identifier is used to determine an updated value to be displayed in the particular cell of the other logical table.

Abstract: Systems and methods are described to generate reverse dependency lists for cells in a workbook data store. In one aspect, a system populates, for a first cell in the data store, a reverse dependency list identifying a second cell, wherein the second cell comprises a second cell value that depends, at least in part, on a first cell value of the first cell. The system then detects a change to cell information for the first cell, and based on the detected change to the cell information: marks the second cell for recalculation based on the second cell being identified in the reverse dependency list for the first cell and the detected change to the cell information. For each marked cell, the system performs recalculation on the marked cell, performs recalculation recursively on any cells on which the marked cell depends, and stores recalculated cell values in a recalculated cache.

Abstract: Aspects are described to generate indexing on columns including links to other columns in a different table. One aspect describes a computer-implemented method comprising identifying, for a workbook comprising a plurality of cells and tables stored in a spreadsheet structure, a query comprising a formula, parsing the formula to identify, as one operand, a heterogeneous column of links in a first table of the plurality of tables to a column in a second table of the plurality of tables and at least one operator, automatically generating a virtual column for the heterogeneous column, the virtual column being inaccessible to a user, storing the generated virtual column, evaluating the function of the virtual column for each row of the first table, generating an inaccessible virtual index for the virtual column, storing the virtual index, and evaluating the formula based on the virtual index to generate a result.

Abstract: A phosphoinositide 3-kinase inhibitor for use in the treatment of pancreatic cancer and a method for treatment of pancreatic cancer including administration of an phosphoinositide 3-kinase inhibitor an Src inhibitor to a human subject in need thereof. There is also provided a pharmaceutical composition comprising a phosphoinositide 3-kinase inhibitor and an Src inhibitor.

Abstract: A descriptor of a dynamically materialized view is stored. The descriptor includes a query to select a subset of cells from a data sheet, and a result of executing the query. In response to an update directed to the data sheet, the result stored in the descriptor is modified based on re-executing the query, and a notification is transmitted to an execution platform at which an application whose output depends on the dynamically materialized view runs.

Abstract: A phosphoinositide 3-kinase inhibitor for use in the treatment of pancreatic cancer and a method for treatment of pancreatic cancer including administration of an phosphoinositide 3-kinase inhibitor an Src inhibitor to a human subject in need thereof. There is also provided a pharmaceutical composition comprising a phosphoinositide 3-kinase inhibitor and an Src inhibitor.

Abstract: A descriptor of a dynamically materialized view is stored. The descriptor includes a query to select a subset of cells from a data sheet, and a result of executing the query. In response to an update directed to the data sheet, the result stored in the descriptor is modified based on re-executing the query, and a notification is transmitted to an execution platform at which an application whose output depends on the dynamically materialized view runs.

Abstract: In response to a determination that a first logical table is to be created in a data sheet, a respective row identifier is generated and stored for individual rows of the first logical table. To indicate a relationship between a particular cell of another logical table and a particular row of the first logical table, the row identifier of the particular row is stored. After a modification of a value stored in the particular row, the row identifier is used to determine an updated value to be displayed in the particular cell of the other logical table.

Abstract: This disclosure relates generally to clinical trial management, and more particularly to method of performing a data driven cognitive clinical trial feasibility analysis. In one embodiment, the method comprising (a) receiving, a plurality of protocol requirements to initiate a clinical trial site feasibility; (b) identifying, a plurality of meta-data for at least one protocol requirement from the plurality of protocol requirements; (c) obtaining, an exhaustive list of historic clinical trial site data for the identified meta-data from a site data repository; (d) obtaining, an exhaustive list of third party clinical trial site data for identified meta-data from a third party data repository; and (e) assessing, the exhaustive list of clinical trial site data and the exhaustive list of third party clinical trial site data to obtain a list of identified clinical trial site feasibility.

Abstract: In response to a determination that a first logical table is to be created in a data sheet, a respective row identifier is generated and stored for individual rows of the first logical table. To indicate a relationship between a particular cell of another logical table and a particular row of the first logical table, the row identifier of the particular row is stored. After a modification of a value stored in the particular row, the row identifier is used to determine an updated value to be displayed in the particular cell of the other logical table.

Abstract: This disclosure relates generally to clinical trial management, and more particularly to method of performing a data driven cognitive clinical trial feasibility analysis. In one embodiment, the method comprising (a) receiving, a plurality of protocol requirements to initiate a clinical trial site feasibility; (b) identifying, a plurality of meta-data for at least one protocol requirement from the plurality of protocol requirements; (c) obtaining, an exhaustive list of historic clinical trial site data for the identified meta-data from a site data repository; (d) obtaining, an exhaustive list of third party clinical trial site data for identified meta-data from a third party data repository; and (e) assessing, the exhaustive list of clinical trial site data and the exhaustive list of third party clinical trial site data to obtain a list of identified clinical trial site feasibility.

Abstract: Methods and systems for reconciling firm account data and exchange account data are provided. Firm account data and exchange account data are compared and discrepancies are displayed on a display device. A user may receive additional information about the data that does not match by selecting appropriate hyperlinks or other navigational items. The user may also enter adjustments.