Patents by Inventor Anupama Natarajan

Anupama Natarajan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PATTERNED CARDIOMYOCYTE CULTURE ON MICROELECTRODE ARRAY
    Publication number: 20160305927
    Abstract: The invention provides a culture of patterned cardiomyocytes, the culture including a support substrate bearing a multielectrode array, a negative surface resistant to cell attachment and deposited on the support substrate covering the multi-electrode array, a pattern ablated on the negative surface, a positive surface promoting cell attachment deposited on the pattern ablated on the negative surface; and cardiomyocytes adherent to the positive surface and growing aligned along the pattern ablated on the negative surface. The invention also includes a method of making the culture of patterned cardiomyocytes and a method of in vitro method of testing the effect of a compound on cardiac function by measuring electrical output from the patterned cardiomyocytes.
    Type: Application
    Filed: June 23, 2016
    Publication date: October 20, 2016
    Inventors: Peter Molnar, Anupama Natarajan, Maria Stancescu, James Hickman
  • Patterned cardiomyocyte culture on microelectrode array
    Patent number: 9404140
    Abstract: The invention provides a culture of patterned cardiomyocytes, the culture including a support substrate bearing a multielectrode array, a negative surface resistant to cell attachment and deposited on the support substrate covering the multi-electrode array, a pattern ablated on the negative surface, a positive surface promoting cell attachment deposited on the pattern ablated on the negative surface; and cardiomyocytes adherent to the positive surface and growing aligned along the pattern ablated on the negative surface. The invention also includes a method of making the culture of patterned cardiomyocytes and a method of in vitro method of testing the effect of a compound on cardiac function by measuring electrical output from the patterned cardiomyocytes.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: August 2, 2016
    Assignee: The University of Central Florida Research Foundation, Inc.
    Inventors: Peter Molnar, Anupama Natarajan, Maria Stancescu, James Hickman