Abstract: A method (1100) of fabricating a personalised orthopaedic cast (900) is disclosed. The method (1100) includes 3D scanning of a body part of a user, generating a Computer Aided Design (CAD) of an orthopaedic cast (900) for the scanned body part, and simulating real-life conditions to determine mechanical stability of the modelled cast. The mechanical stability is determined through Finite Element Analysis (FEA). The method (1100) includes determining whether the mechanical stability of the modelled cast is acceptable. The method (1100) includes finalising the CAD model when the mechanical stability of the modelled cast is found to be acceptable. The method (1100) includes 3D printing the finalised CAD model to fabricate the personalised orthopaedic cast (900).

Abstract: The present disclosure describes methods of using ultrasound to engineer cartilage, as well as a bioreactor that includes at least one ultrasound transducer.

Abstract: User behavior data can be used with language-specific rule sets to generate stemming databases useful for such tasks as indexing and search query processing. The terms contained in user queries, as well as user behavior with respect to those queries or results returned for those queries, can be analyzed to determine a relative measure (e.g., relative frequency) of various forms of those terms. When generating a stemming database, language-specific rule sets can be used to determine appropriate stemming rules, and where more than one potential rule is identified the user behavior data can be used to select what is likely the appropriate rule, at least for the respective environment. Whitelists or other such components can be used to handle specific or irregular forms that do not follow the general rules or otherwise are exceptions that might not otherwise be processed correctly.

Abstract: The present disclosure describes methods of using ultrasound in tissue culture and tissue engineering, as well as a bioreactor that includes at least one ultrasound transducer.

Abstract: A method is disclosed for coupling a ligand within a porous support. The method involves mixing ligand and porous support under conditions sufficient to suppress coupling conditions of the ligand to the porous support while enhancing the relative rate of diffusion, to the rate of reaction, of the ligand into and within the porous support, and then altering the conditions to enhance rapid coupling of the ligand within the porous support. The alteration from diffusion conditions to coupling conditions involves a change in the reaction solution of pH, ionic strength, temperature, coupling competitor, such that a relatively lower Thiele Modulus during diffusion conditions changes to a relatively higher Thiele Modulus during coupling conditions. Derivatized porous supports produced according to the method are also disclosed. The derivatized porous support has enhanced functional efficiency. Derivatized porous supports prepared from azlactone-functional porous supports are also disclosed.