Patents by Inventor Anusuya Choudhury

Anusuya Choudhury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pegylated drug-linkers and intermediates thereof
    Patent number: 11844839
    Abstract: The present invention provides improved processes for the preparation of auristatin drug-linkers with a PEG unit, as well as intermediates thereof.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: December 19, 2023
    Assignee: Seagen Inc.
    Inventors: Yunyu Mao, Philip Moquist, Anusuya Choudhury, Wendel Doubleday
  • Process for the preparation of glucuronide drug-linkers and intermediates thereof
    Patent number: 11730822
    Abstract: The present invention provides improved processes for the preparation of drug-linkers with a ?-glucuronide cleavable unit, as well as intermediates thereof.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: August 22, 2023
    Assignee: Seagen Inc.
    Inventors: Yunyu Mao, Philip Moquist, Anusuya Choudhury, Wendel Doubleday
  • PROCESS FOR THE PREPARATION OF GLUCURONIDE DRUG-LINKERS AND INTERMEDIATES THEREOF
    Publication number: 20200222553
    Abstract: The present invention provides improved processes for the preparation of drug-linkers with a ?-glucuronide cleavable unit, as well as intermediates thereof.
    Type: Application
    Filed: March 23, 2018
    Publication date: July 16, 2020
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Yunyu Mao, Philip Moquist, Anusuya Choudhury, Wendel Doubleday
  • PROCESS FOR THE PREPARATION OF PEGYLATED DRUG-LINKERS AND INTERMEDIATES THEREOF
    Publication number: 20190388546
    Abstract: The present invention provides improved processes for the preparation of auristatin drug-linkers with a PEG unit, as well as intermediates thereof.
    Type: Application
    Filed: March 24, 2017
    Publication date: December 26, 2019
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Yunyu Mao, Philip Moquist, Anusuya Choudhury, Wendel Doubleday
  • MODULATORS FOR ATP-BINDING CASSETTE TRANSPORTERS
    Publication number: 20160166540
    Abstract: Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
    Type: Application
    Filed: January 11, 2016
    Publication date: June 16, 2016
    Inventors: Adam Looker, Benjamin Joseph Littler, Anusuya Choudhury, Christian Harrison, Ravikanth Veluri, Michael P. Ryan, Licong Jiang, Eduard Luss-Lusis
  • Synthesis of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4)-yl)piperidine-2,6-dione
    Patent number: 9303014
    Abstract: Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: April 5, 2016
    Assignee: Celgene Corporation
    Inventors: Alexander L. Ruchelman, Benjamin M. Cohen, Anusuya Choudhury, Matthew M. Kreilein, William W. Leong, Hon-Wah Man
  • Synthesis of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4)-yl)piperidine-2,6-dione
    Patent number: 9266858
    Abstract: Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: February 23, 2016
    Assignee: Celgene Corporation
    Inventors: Alexander L. Ruchelman, Benjamin M. Cohen, Anusuya Choudhury, Matthew M. Kreilein, William W. Leong, Hon-Wah Man
  • Modulators of ATP-binding cassette transporters
    Patent number: 9254291
    Abstract: Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: February 9, 2016
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Adam Looker, Benjamin Joseph Littler, Anusuya Choudhury, Cristian Harrison, Ravikanth Veluri, Michael P. Ryan, Licong Jiang, Eduard Luss-Lusis
  • SYNTHESIS OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL)PIPERIDINE-2,6-DIONE
    Publication number: 20160009685
    Abstract: Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 24, 2015
    Publication date: January 14, 2016
    Inventors: Alexander L. RUCHELMAN, Benjamin M. COHEN, Anusuya CHOUDHURY, Matthew M. KREILEIN, William W. LEONG, Hon-Wah MAN
  • SYNTHESIS OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL)PIPERIDINE-2,6-DIONE
    Publication number: 20150274694
    Abstract: Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 10, 2015
    Publication date: October 1, 2015
    Inventors: Alexander L. RUCHELMAN, Benjamin M. COHEN, Anusuya CHOUDHURY, Matthew M. KREILEIN, William W. LEONG, Hon-Wah MAN
  • Methods of synthesis and purification of heteroaryl compounds
    Patent number: 9079900
    Abstract: Provided herein are methods to prepare Heteroaryl Compounds having the following structure: wherein R1-R4 are as defined herein. The Heteroaryl compounds are useful for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: July 14, 2015
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Roy L. Harris, John Sapienza, Graziella Shevlin, Patrick Papa, Branden Gingsee Lee, Garrick Packard, Jingjing Zhao, Patrick Anthony Jokiel, Deborah Mortensen, Jennifer Riggs, Juan Antonio Gamboa, Marie Georges Beauchamps, Matthew Michael Kreilein, Mohit Atul Kothare, Sophie Perrin-Ninkovic, Philip Pye, William Wei-Hwa Leong, Jan Elsner, Anusuya Choudhury
  • Synthesis of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4)-yl)piperidine-2,8-dione
    Patent number: 9067912
    Abstract: Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: June 30, 2015
    Assignee: Celgene Corporation
    Inventors: Alexander L. Ruchelman, Benjamin M. Cohen, Anusuya Choudhury, Matthew M. Kreilein, William W. Leong, Hon-Wah Man
  • SYNTHESIS OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL)PIPERIDINE-2,6-DIONE
    Publication number: 20140330016
    Abstract: Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 30, 2014
    Publication date: November 6, 2014
    Applicant: CELGENE CORPORATION
    Inventors: Alexander L. RUCHELMAN, Benjamin M. COHEN, Anusuya CHOUDHURY, Matthew M. KREILEIN, William W. LEONG, Hon-Wah MAN
  • METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
    Publication number: 20140155593
    Abstract: Provided herein are methods to prepare Heteroaryl Compounds having the following structure: wherein R1-R4 are as defined herein. The Heteroaryl compounds are useful for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
    Type: Application
    Filed: February 7, 2014
    Publication date: June 5, 2014
    Applicant: SIGNAL PHARMACEUTICALS, LLC
    Inventors: Roy L. Harris, John Sapienza, Graziella Shevlin, Patrick Papa, Branden Gingsee Lee, Garrick Packard, Jingjing Zhao, Patrick Anthony Jokiel, Deborah Mortensen, Jennifer Riggs, Juan Antonio Gamboa, Marie Georges Beauchamps, Matthew Michael Kreilein, Mohit Atul Kothare, Sophie Perrin-Ninkovic, Philip Pye, William Wei-Hwa Leong, Jan Elsner, Anusuya Choudhury
  • Methods of synthesis and purification of heteroaryl compounds
    Patent number: 8686135
    Abstract: Provided herein are methods to prepare Heteroaryl Compounds having the following structure: wherein R1-R4 are as defined herein. The Heteroaryl compounds are useful for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: April 1, 2014
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Patrick Anthony Jokiel, Juan Antonio Gamboa, Philip Pye, William Wei-Hwa Leong, Anusuya Choudhury
  • Process for the preparation of piperazinyl and diazepanyl benzamide derivatives
    Patent number: 8680273
    Abstract: The present invention is directed to a novel process for the preparation of piperazinyl and diazepanyl benzamide derivatives, useful for the treatment of disorders and conditions mediated by a histamine receptor, preferably the H3 receptor.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: March 25, 2014
    Assignee: Janssen Pharmaceutica NV
    Inventors: Anusuya Choudhury, Jeffrey S. Grimm, Kirk L. Sorgi, David Palmer, Jing Liu
  • Methods of synthesis and purification of heteroaryl compounds
    Patent number: 8569494
    Abstract: Provided herein are methods to prepare Heteroaryl Compounds having the following structure: wherein R1-R4 are as defined herein. The Heteroaryl compounds are useful for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: October 29, 2013
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Roy L. Harris, John Sapienza, Graziella Shevlin, Patrick Papa, Branden Gingsee Lee, Garrick Packard, Jingjing Zhao, Patrick Anthony Jokiel, Deborah Mortensen, Jennifer Riggs, Juan Antonio Gamboa, Marie Georges Beauchamps, Matthew Michael Kreilein, Mohit Atul Kothare, Sophie Perrin-Ninkovic, Philip James Pye, William Wei-Hwa Leong, Jan Elsner, Anusuya Choudhury
  • METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
    Publication number: 20130245254
    Abstract: Provided herein are methods to prepare Heteroaryl Compounds having the following structure: wherein R1-R4 are as defined herein. The Heteroaryl compounds are useful for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.
    Type: Application
    Filed: April 30, 2013
    Publication date: September 19, 2013
    Applicant: SIGNAL PHARMACEUTICALS, LLC
    Inventors: Roy L. Harris, John Sapienza, Graziella Shevlin, Patrick Papa, Branden Gingsee Lee, Garrick Packard, Jingjing Zhao, Patrick Anthony Jokiel, Deborah Mortensen, Jennifer Riggs, Juan Antonio Gamboa, Marie Georges Beauchamps, Matthew Michael Kreilein, Mohit Atul Kothare, Sophie Perrin-Ninkovic, Philip Pye, William Wei-Hwa Leong, Jan Elsner, Anusuya Choudhury
  • Process for preparing substituted diaminopyrimidine oximes
    Patent number: 8278446
    Abstract: The present invention is directed to a process for chemoselective substitution on a halopyrimidine carboxaldehyde having multiple reactive sites and subsequent stereoselective oxime formation.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: October 2, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Hongfeng Chen, Peter J. Connolly, Kirk L. Sorgi, Anusuya Choudhury, Christopher N. Nilsen
  • PROCESS FOR THE PREPARATION OF PIPERAZINYL AND DIAZEPANYL BENZAMIDE DERIVATIVES
    Publication number: 20110105752
    Abstract: The present invention is directed to a novel process for the preparation of piperazinyl and diazepanyl benzamide derivatives, useful for the treatment of disorders and conditions mediated by a histamine receptor, preferably the H3 receptor.
    Type: Application
    Filed: January 10, 2011
    Publication date: May 5, 2011
    Inventors: Anusuya Choudhury, Jeffrey S. Grimm, Kirk L. Sorgi, David Palmer, Jing Liu