Patents by Inventor Anvarhusein Isab
Anvarhusein Isab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11981690Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: GrantFiled: May 26, 2022Date of Patent: May 14, 2024Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman
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Patent number: 11958867Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: GrantFiled: May 26, 2022Date of Patent: April 16, 2024Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman
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Publication number: 20240059719Abstract: The present invention relates to a gold complex having a compound of formula (I) as anticancer or chemotherapeutic agent. The present invention also relates to method of preparation of such complexes, pharmaceutical compositions containing such complexes and further extends to a method of treating or diagnosing a subject/patient suffering from cancer using such complexes.Type: ApplicationFiled: October 25, 2023Publication date: February 22, 2024Inventors: Haseeb Ahmad Khan, Abdullah S. Alhomida, Anvarhusein A. Isab, Mansour K. Gatasheh, Ali Al-Hoshani, N Rajendra Prasad
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Publication number: 20230109755Abstract: Systems and methods for remote command access in a hybrid cloud to on-premises devices are described. An example method includes receiving, by a gateway service, a request for a connection between a remote support service agent and an on-premises device. The method further includes receiving, by the gateway service, consent from an authorized user associated with the on-premises device. The method further includes creating, by the gateway service, a first session with the on-premises device, where a scope of the consent is limited to the first session. The method further includes provisioning, by the gateway service, a device-specific hybrid connection endpoint for the first session. The method further includes forming, by the gateway service a secure session by binding the device-specific hybrid connection endpoint with a second session, the secure session allowing for transport of data and a set of commands based on a scope of the consent.Type: ApplicationFiled: December 30, 2021Publication date: April 13, 2023Inventors: Faraz H. QADRI, Aniket A. MALATPURE, Swapnil T. ASHTEKAR, GREESHMA VIJAYAKUMAR, Shireen Anvarhusein ISAB, Mohit Kumar GARG, Phani Prakash BOPPANA, Trivikram SOMISETTY
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Patent number: 11571430Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.Type: GrantFiled: February 1, 2021Date of Patent: February 7, 2023Assignees: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Adam Ahmed Abdullah Sulaiman, Abdul Rajjak Shaikh, Ali Alhoshani, Anvarhusein A. Isab
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Patent number: 11472819Abstract: The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.Type: GrantFiled: January 27, 2020Date of Patent: October 18, 2022Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Adam A. A. Sulaiman
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Patent number: 11459343Abstract: The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.Type: GrantFiled: January 27, 2020Date of Patent: October 4, 2022Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Adam A. A. Sulaiman
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Patent number: 11453684Abstract: The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.Type: GrantFiled: January 27, 2020Date of Patent: September 27, 2022Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Adam A. A. Sulaiman
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Publication number: 20220281896Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: ApplicationFiled: May 26, 2022Publication date: September 8, 2022Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN
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Publication number: 20220281897Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: ApplicationFiled: May 26, 2022Publication date: September 8, 2022Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN
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Patent number: 11384100Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: GrantFiled: August 28, 2019Date of Patent: July 12, 2022Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman
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Patent number: 11142539Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: GrantFiled: March 10, 2020Date of Patent: October 12, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman, Ali Alhoshani
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Publication number: 20210284674Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN, Ali ALHOSHANI
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Publication number: 20210283140Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.Type: ApplicationFiled: February 1, 2021Publication date: September 16, 2021Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Adam Ahmed Abdullah SULAIMAN, Abdul Rajjak SHAIKH, Ali ALHOSHANI, Anvarhusein A. ISAB
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Patent number: 11117912Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: GrantFiled: March 10, 2020Date of Patent: September 14, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarhusein A. Isab
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Publication number: 20210061818Abstract: A gold(III) complex of formula (I) or formula (II) wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; R3 and R4 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, an optionally substituted aryl, an optionally substituted heterocyclyl, an optionally substituted alkoxy, a hydroxyl, a halo, a nitro, a cyano, a N-monosubstituted amino group, or a N,N-disubstituted amino group; and X is Cl, Br, or I. A pharmaceutical composition containing the gold(III) complex of formula (I) or (II), and a method of treating cancer are included.Type: ApplicationFiled: August 28, 2019Publication date: March 4, 2021Applicant: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN
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Publication number: 20200299313Abstract: The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.Type: ApplicationFiled: January 27, 2020Publication date: September 24, 2020Applicant: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. ISAB, Adam A. A. SULAIMAN
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Publication number: 20200299311Abstract: The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.Type: ApplicationFiled: January 27, 2020Publication date: September 24, 2020Applicant: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. ISAB, Adam A.A. SULAIMAN
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Publication number: 20200299312Abstract: The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.Type: ApplicationFiled: January 27, 2020Publication date: September 24, 2020Applicant: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. ISAB, Adam A. A. SULAIMAN
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Patent number: 10562928Abstract: The invention is directed to platinum(II) complexes comprising dithiocarbamates and methods for treating cancer using these complexes.Type: GrantFiled: August 16, 2019Date of Patent: February 18, 2020Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Muhammad Altaf, Muhammad Ali Ehsan, Khalid Omer