Patents by Inventor Anwesha Dey

Anwesha Dey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148733
    Abstract: Provided herein is a combination, comprising: (i) one or more YAP/TAZ-TEAD inhibitors; and (ii) one or more KRAS inhibitors, such as the specific YAP/TAZ-TEAD inhibitors and KRAS inhibitors described herein. Also provided herein are methods of modulating or inhibiting KRAS activity in a cell, comprising administering to the cell an effective amount of such combinations. Also provided herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an effective amount of such combinations.
    Type: Application
    Filed: November 15, 2023
    Publication date: May 9, 2024
    Inventors: Anwesha DEY, Marie EVANGELISTA
  • Publication number: 20230310455
    Abstract: Provided are combination therapies comprising inavolisib (a.k.a. GDC-0077) and other HER2-targeted therapies (e.g., pertuzumab and trastuzumab) for the treatment of HER2-positive cancers; and methods of treating HER2 positive (HER2+) cancers in a patient (preferably a patient with a PIK3CA mutant breast cancer) comprising administering a therapeutically effective amount of inavolisib and a HER2-targeted therapy (e.g., trastuzumab, pertuzumab, or a combination of trastuzumab and pertuzumab).
    Type: Application
    Filed: June 9, 2023
    Publication date: October 5, 2023
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Jennifer Lee Schutzman, Chunyan Song, Kyung Wha Song, Eirini Thanopoulou, Simon Peter Warburton, Anwesha Dey, Stephanie Royer Joo
  • Publication number: 20230203062
    Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: November 21, 2022
    Publication date: June 29, 2023
    Applicant: Genentech, Inc.
    Inventors: Jason Robert ZBIEG, Paul Powell BEROZA, Vishal Anil VERMA, Bing-Yan ZHU, Ramsay BEVERIDGE, Liang ZHAO, Melissa LEBLANC, Lisa Marie BARTON, Bryan Ka Ip CHAN, Samir BOUAYAD-GERVAIS, Anwesha DEY, Marie Anne EVANGELISTA, Russell Tyler SMITH
  • Publication number: 20230202984
    Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: November 21, 2022
    Publication date: June 29, 2023
    Applicant: Genentech, Inc.
    Inventors: Jason Robert Zbieg, Russell Tyler Smith, Paul Powell Beroza, Vishal Anil Verma, Bing-Yan Zhu, Ramsay Beveridge, Lisa Marie Barton, Bryan Ka lp Chan, Curtis Colwell, Samir Bouayad-Gervais, Anwesha Dey, Marie Anne Evangelista