Patents by Inventor Ao-an WANG

Ao-an WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pan-RAF kinase inhibitor and use thereof
    Patent number: 12115152
    Abstract: The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: October 15, 2024
    Assignee: TARAPEUTICS SCIENCE INC.
    Inventors: Qing Song Liu, Jing Liu, Xi Xiang Li, Ao Li Wang, Zi Ping Qi, Qing Wang Liu, Zong Ru Jiang, Feng Ming Zou, Wen Chao Wang, Chen Hu, Cheng Chen, Li Wang
  • PYRAZOLE DERIVATIVES AND USE THEREOF
    Publication number: 20220288064
    Abstract: Provided is a novel PDGFR kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. Further provided are use and a method of the compound of formula (I) for preventing or treating conditions associated with PDGFR kinase activity, particularly use and a method for preventing or treating conditions associated with PDGFR? and/or PDGFR? kinase activity.
    Type: Application
    Filed: August 14, 2020
    Publication date: September 15, 2022
    Applicant: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES
    Inventors: Qing Song LIU, Jing LIU, Xi Xiang LI, Ao Li WANG, Feng Ming ZOU, Cheng CHEN, Qing Wang LIU, Juan LIU, Jiang Yan CAO, Wen Liang WANG, Shuang QI, Wen Chao WANG, Bei Lei WANG, Li WANG
  • NOVEL PAN-RAF KINASE INHIBITOR AND USE THEREOF
    Publication number: 20220143001
    Abstract: The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.
    Type: Application
    Filed: March 7, 2019
    Publication date: May 12, 2022
    Applicant: TARAPEUTICS SCIENCE INC.
    Inventors: Qing Song LIU, Jing LIU, Xi Xiang LI, Ao Li WANG, Zi Ping QI, Qing Wang LIU, Zong Ru JIANG, Feng Ming ZOU, Wen Chao WANG, Chen HU, Cheng CHEN, Li WANG
  • Ball float type liquidometer with vernier display
    Patent number: 10788354
    Abstract: Disclosed is a ball float type liquidometer with moving indicator, comprising a ball float chamber and a ferromagnetic spherical ball float provided therein, a moving indicator outside the ball float chamber, a calibrated scale and a moving indicator guide rail, wherein the moving indicator comprises a magnetic steel member, a frame and a rolling system which is horizontally fixed and sheathed in the frame; the rolling system comprises rolling wheels provided with radial grooves along a circumferential surface, rolling bearings and shafts; the magnetic steel member is located between the ball float chamber and the frame and is fixed outside one side face close to the ball float chamber on the frame, and a magnetic pole of the magnetic steel member is directly oriented towards the ball float.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: September 29, 2020
    Assignee: DALIAN JIAXIN ELECTROMECHANICAL INSTRUMENT CO. LTD.
    Inventors: Jiaxian Wang, Ao-an Wang, Xiaori Wang, Zhenqiang Gao
  • EZH2 inhibitor and use thereof
    Patent number: 10647700
    Abstract: An inhibitor of a wild type and Y641F mutant of human histone methyltransferase EZH2 is provided herein. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat a cancer or precancerous condition related to EZH2 activity.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: May 12, 2020
    Assignee: TARAPEUTICS SCIENCE INC.
    Inventors: Qingsong Liu, Jing Liu, Fengchao Lv, Chen Hu, Wen Liang Wang, Ao Li Wang, Zi Ping Qi, Xiao Fei Liang, Wen Chao Wang, Tao Ren, Bei Lei Wang, Li Wang
  • EZH2 INHIBITOR AND USE THEREOF
    Publication number: 20190367482
    Abstract: An inhibitor of a wild type and Y641 F mutant of human histone methyltransferase EZH2 is provided herein. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat a cancer or precancerous condition related to EZH2 activity.
    Type: Application
    Filed: January 17, 2018
    Publication date: December 5, 2019
    Applicant: TARAPEUTICS SCIENCE INC.
    Inventors: Qingsong LIU, Jing LIU, Fengchao LV, Chen HU, Wen Liang WANG, Ao Li WANG, Zi Ping Qi, Xiao Fei LIANG, Wen Chao WANG, Tao REN, Bei Lei WANG, Li WANG
  • BALL FLOAT TYPE LIQUIDOMETER WITH VERNIER DISPLAY
    Publication number: 20180348045
    Abstract: Disclosed is a ball float type liquidometer with moving indicator, comprising a ball float chamber and a ferromagnetic spherical ball float provided therein, a moving indicator outside the ball float chamber, a calibrated scale and a moving indicator guide rail, wherein the moving indicator comprises a magnetic steel member, a frame and a rolling system which is horizontally fixed and sheathed in the frame; the rolling system comprises rolling wheels provided with radial grooves along a circumferential surface, rolling bearings and shafts; the magnetic steel member is located between the ball float chamber and the frame and is fixed outside one side face close to the ball float chamber on the frame, and a magnetic pole of the magnetic steel member is directly oriented towards the ball float.
    Type: Application
    Filed: October 20, 2016
    Publication date: December 6, 2018
    Applicant: DALIAN JIAXIN ELECTROMECHANICAL INSTRUMENT CO. LTD .
    Inventors: Jiaxian WANG, Ao-an WANG, Xiaori WANG, Zhenqiang GAO