Patents by Inventor Ao Chen

Ao Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250145839
    Abstract: An intumescent fire-retardant and anti-corrosive coating modified by polyaniline-silicon carbide and a preparation method thereof are provided, the coating includes a compound A and a compound B. The compound A includes a waterborne epoxy resin emulsion, polyaniline-silicon carbide composite material, fire-retardant filler, titanium dioxide, aluminum hydroxide, talc powder, a wetting dispersant, a defoaming agent, a flow agent and water, the compound B includes an epoxy hardener. The polyaniline-silicon carbide composite material is prepared from silicon carbide, phenylamine, protonic acid and an oxidizing agent through an ice bath. The polyaniline-silicon carbide composite material can enhance dispersion in the emulsion through the organic-inorganic composite, and silicon carbide has high thermal stability and good density, while polyaniline serves as a material with unique fire-retardant properties.
    Type: Application
    Filed: June 24, 2024
    Publication date: May 8, 2025
    Inventors: Dan Jia, Yijie Jin, Haitao Duan, Shengpeng Zhan, Tian Yang, Ao Chen, Hualong Yu, Lixin Ma, Xiaoshuang Luo
  • Publication number: 20250129407
    Abstract: The present application relates to transcriptome sequencing and biomolecule space information detection. Specifically, the present application relates to a method for positioning and labeling a nucleic acid molecule, a method for constructing a nucleic acid molecule library for transcriptome sequencing, and a kit for implementing the method.
    Type: Application
    Filed: December 24, 2021
    Publication date: April 24, 2025
    Inventors: Sha LIAO, Ao CHEN, Wenwei ZHANG, Xun XU, Jian PENG, Wenjiao LI, Xi CHEN, Defeng FU
  • Publication number: 20250059530
    Abstract: Provided are a method for positioning and labeling a nucleic acid molecule, and a method for constructing a nucleic acid molecule library for single-cell transcriptome sequencing, which relate to the technical fields of single-cell transcriptome sequencing and biomolecular space information detection. Further provided are a nucleic acid molecule library constructed by using the method, and a kit for implementing the method.
    Type: Application
    Filed: November 30, 2022
    Publication date: February 20, 2025
    Inventors: Sha LIAO, Ao CHEN, Wenwei ZHANG, Xun XU
  • Publication number: 20250043273
    Abstract: A DNA library sequence for increasing the number of chip probes and an application thereof. The DNA library sequence comprises two or more position information labeling sequences and three or more fixed sequences, wherein the position information labeling sequences and the fixed sequences are arranged at intervals. The DNA library sequence increases the number of probes of a chip used for spatiotemporal omics, and then a capture number of transcript genes is increased. The present invention has a very high application prospect.
    Type: Application
    Filed: December 24, 2021
    Publication date: February 6, 2025
    Inventors: Sha LIAO, Ao CHEN, Wenwei ZHANG, Xun XU, Xi CHEN, Defeng FU
  • Publication number: 20240402754
    Abstract: A method for performing clock compensation in a communication device includes: determining a clock difference between a source operating clock and a target operating clock; performing clock compensation according to the clock difference, thereby obtaining a compensated time; and according to the compensated time, performing a clock synchronization process based on precision time protocol.
    Type: Application
    Filed: January 17, 2024
    Publication date: December 5, 2024
    Applicant: Realtek Semiconductor Corp.
    Inventors: I-Hsueh Lin, Pen-Ao Chen
  • Publication number: 20240375096
    Abstract: Provided are a detection structure and method, a detection chip, and a sensing device. The detection structure (200) includes a sensing device (100) at least including a detection chip (000), a fluid tank (101), and a carrier plate (102), and a detector (201) configured to capture and analyze a signal generated in the sensing device (100). The fluid tank (101) is disposed at the carrier plate (102) and forms a cavity (103) with the carrier plate (102). The detection chip (000) is located in the cavity (103) and at least includes a substrate (001), a first electrode (002) and a first circuit (003) that are disposed at the substrate. The first electrode (002) is connected to a second electrode (004) through the first circuit (003) to form an electrical circuit.
    Type: Application
    Filed: August 31, 2021
    Publication date: November 14, 2024
    Inventors: Quanxin YUN, Zhaohui WANG, Yuxiang LI, Ao CHEN, Wenwei ZHANG, Xun XU
  • Publication number: 20240279724
    Abstract: Provided is a method for obtaining a double-stranded sequence by single-stranded rolling circle amplification, comprising: 1) performing rolling circle amplification reaction on single-stranded circular DNA by means of a first primer to obtain an amplified sequence, the first primer being complementary to a partial region of the single-stranded circular DNA, and the single-stranded circular DNA having a break mechanism that can cause the single-stranded circular DNA to ring-open; 2) ring-opening the single-stranded circular DNA by means of the break mechanism to obtain single-stranded linear DNA; and 3) using the single-stranded linear DNA as a second primer and using the amplified sequence obtained in step 1) as a template to perform amplification reaction to obtain an amplified double-stranded sequence.
    Type: Application
    Filed: June 16, 2021
    Publication date: August 22, 2024
    Inventors: Ji Wang, Tao Tan, Lin Zhou, Ou Wang, Wenwei Zhang, Ao Chen
  • Publication number: 20240209439
    Abstract: The present invention relates to the field of nucleic acid sequencing. Specifically, provided in the present invention is a nucleotide analogue for sequencing. The nucleotide analogue carries a linker on the base or the ribose ring 3?-OH, and can be used for NGS sequencing. The present invention further relates to a kit containing the nucleotide analogue, and a sequencing method based on the nucleotide analogue.
    Type: Application
    Filed: March 31, 2022
    Publication date: June 27, 2024
    Inventors: Xun XU, Bo TENG, Wenwei ZHANG, Liang SHEN, Shitian ZHUO, Shengyi YAN, Nanfeng GAO, Yonghui ZHANG, Jie ZHAO, Sha LIAO, Ming WANG, Shaoqiao ZHANG, Ao CHEN, Handong LI
  • Patent number: 11993813
    Abstract: A nucleic acid probe and a nucleic acid sequencing method for performing sequencing while ligating nucleic acids. The nucleic acid probe is a DNA sequencing probe, comprising a first moiety, a second moiety, a linker, and a detectable label. A base of the first moiety is A, T, U, C, or G, a base of the second moiety is a random base and/or a universal base, and 3 bases or more are present in the second moiety. The first moiety and the second moiety are ligated via the linker, the connection between the first moiety and the ligation can be cleaved, and the detectable label is ligated to the second moiety or the linker. The above probe, a combination formed therewith, or a sequencing method using the same can reduce the number or types of probes in nucleic acid sequencing, thereby reducing cost.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: May 28, 2024
    Assignee: MGI TECH CO., LTD.
    Inventors: Erkai Liu, Wenwei Zhang, Ao Chen, Chongjun Xu
  • Patent number: 11949117
    Abstract: A battery includes a plurality of energy storage units, a flexible linkage arranged to physically and electrically connect each adjacent pair of energy storage units, and an encapsulation arranged to encapsulate the energy storage units and the linkages. The energy storage units are movable with respect to each other via the flexible linkage within each adjacent pair of energy storage units in the encapsulation.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: April 2, 2024
    Assignee: City University of Hong Kong
    Inventors: Chunyi Zhi, Ao Chen, Zijie Tang
  • Publication number: 20240067673
    Abstract: A modified nucleoside or nucleotide, the 3?-OH of the modified nucleoside or nucleotide being reversibly blocked; meanwhile, the present invention also relates to a kit comprising the nucleoside or nucleotide, and a sequencing method based on the nucleoside or nucleotide.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 29, 2024
    Inventors: Xun XU, Bo TENG, Wenwei ZHANG, Ao CHEN, Handong LI, Shengyi YAN, Shitian ZHUO, Liang SHEN, Yonghui ZHANG, Nanfeng GAO, Jie ZHAO, Sha LIAO
  • Publication number: 20230323445
    Abstract: The present invention provides a method for sequencing a nucleic acid using an immersion reaction protocol. The immersion reaction protocol comprises sequentially immersing a solid support having nucleic acid molecules immobilized thereon in different reaction containers to realize nucleic acid sequencing. FIG.
    Type: Application
    Filed: May 5, 2023
    Publication date: October 12, 2023
    Inventors: Jin YANG, Xun XU, Hui WANG, Bin XIE, Zhuokun LI, Shengming ZHAO, Ao CHEN, Chongjun XU, Wenwei ZHANG, Ming NI
  • Publication number: 20230272467
    Abstract: The present invention provides a method for sequencing a nucleic acid using an immersion reaction protocol. The immersion reaction protocol comprises sequentially immersing a solid support having nucleic acid molecules immobilized thereon in different reaction containers to realize nucleic acid sequencing.
    Type: Application
    Filed: May 5, 2023
    Publication date: August 31, 2023
    Inventors: Jin Yang, Xun Xu, Hui Wang, Bin Xie, Zhuokun Li, Shengming Zhao, Ao Chen, Chongjun Xu, Wenwei Zhang, Ming Ni
  • Publication number: 20230242979
    Abstract: Provided are a method for sequencing polynucleotides based on optical signal kinetics of luminescent labels and secondary luminescent signals, in which different luminescence forms and luminescence timings are applied to distinguish the sequential incorporation of different nucleotides, so as to realize the sequencing of the polynucleotides.
    Type: Application
    Filed: August 20, 2019
    Publication date: August 3, 2023
    Inventors: Xi Chen, Sha Liao, Wenwei Zhang, Ao Chen, Jie Zhao
  • Patent number: 11692221
    Abstract: The present invention provides a method for sequencing a nucleic acid using an immersion reaction protocol. The immersion reaction protocol comprises sequentially immersing a solid support having nucleic acid molecules immobilized thereon in different reaction containers to realize nucleic acid sequencing.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: July 4, 2023
    Assignees: MGI TECH CO., LTD., COMPLETE GENOMICS, INC.
    Inventors: Jin Yang, Xun Xu, Hui Wang, Bin Xie, Zhuokun Li, Shengming Zhao, Ao Chen, Chongjun Xu, Wenwei Zhang, Ming Ni
  • Publication number: 20230175047
    Abstract: Provided are a method for detecting spatial information of nucleic acids in a sample, as well as a nucleic acid array used in the method and a method for producing the nucleic acid array.
    Type: Application
    Filed: May 14, 2020
    Publication date: June 8, 2023
    Inventors: Ao CHEN, Xun XU, Sha LIAO, Jin YANG, Longqi LIU, Ou WANG, Yuxiang LI, Guoxin TANG, Yuan JIANG, Chongjun XU, Ming NI, Wenwei ZHANG, Radoje DRMANAC, Snezana DRMANAC
  • Patent number: 11649489
    Abstract: Provided are a nucleic acid sequencing method and a nucleic acid sequencing kit. The kit comprises a nucleic acid probe, a ligase, dNTP having a blocking group attached to a 3? end, a polymerase, a reagent 1 for excising the blocking group attached to the 3? end of the dNTP, and a reagent 2 for excising the remaining nucleotides on the nucleic acid probe that are not bound to a to-be-tested base group.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: May 16, 2023
    Assignee: BGI SHENZHEN
    Inventors: Erkai Liu, Wenwei Zhang, Ao Chen, Chongjun Xu
  • Publication number: 20230056313
    Abstract: Provided is a sequencing chip. The sequencing chip includes: a chip main body, nucleic acids, and a phosphonic acid polymer film. The chip main body includes a plurality of chip particles arranged in a same layer, the chip particles are obtained by cutting a chip matrix along cutting lines of a wafer layer, and the chip matrix includes: the wafer layer having the cutting lines uniformly distributed thereon; a first silicon oxide layer made of silicon oxide and formed on an upper surface of the wafer layer; and a transition metal oxide layer made of a transition metal oxide and formed on an upper surface of the first silicon oxide layer. The nucleic acids are fixed on the transition metal oxide layer; and the phosphonic acid polymer film is made of a polyphosphonic acid polymer and formed on an upper surface of the transition metal oxide layer.
    Type: Application
    Filed: October 21, 2022
    Publication date: February 23, 2023
    Applicant: BGI SHENZHEN
    Inventors: Zhaohui Wang, Handong Li, Yuan Li, Wenwei Zhang, Ao Chen
  • Patent number: 11508236
    Abstract: Electronic devices and methods for recognizing driving behavior are provided. The electronic devices may perform the methods to obtain first electronic signals encoding movement data associated with the electronic device from the at least one sensor at a target time point; operate logic circuits to determine whether the first electronic signals encoding movement data meets a precondition; and upon the first electronic signals encoding movement data meeting the precondition, send second electronic signals encoding movement data within a predetermined time period associated with the target time point to a remote server.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: November 22, 2022
    Assignee: BEIJING DIDI INFINITY TECHNOLOGY AND DEVELOPMENT CO., LTD.
    Inventors: Ao Chen, Zhongzhong Xiao, Chong Fan
  • Patent number: 11485966
    Abstract: The present invention provides a method for improving the loading of nucleic acid on a solid support by contacting the solid support with a poloxamer-containing reagent. The present invention also provides a method for improving the stability of a nucleic acid on a solid support, comprising contacting a nucleic acid molecule with a partially double-strand oligonucleotide before or after loading the nucleic acid molecule on a solid support, so as to cause the nucleic acid molecule to hybridize with the oligonucleotide. The present invention also provides a combined use of the two methods.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: November 1, 2022
    Assignees: MGI TECH CO., LTD., COMPLETE GENOMICS, INC.
    Inventors: Hui Wang, Xun Xu, Jin Yang, Ao Chen, Chongjun Xu, Wenwei Zhang