Abstract: Aspects of the present disclosure describe techniques for managing locks in just-in-time compiled code in a software application. An example method generally includes profiling locks by during execution of the JIT compiled code. Locks are generally profiled by identifying locks on resources accessed by the JIT compiled code, and recording access information for each of the identified locks. When a safepoint is reached during execution of the JIT compiled code, one or more locks eligible for conversion to a biased lock are identified .based on the recorded access information for each of the identified locks, one or more locks eligible for conversion to a biased lock. Each respective lock of the one or more eligible locks is converted to a biased lock based on a current lock status of the respective lock.

Abstract: In embodiments, a linac electron beam excited X-ray source weighing less than 50 pounds, and having a volume less than 1 cubic foot, injects electrons from an RF-excited, diamond tip cathode into a dielectric accelerator tube of diameter less than 10 mm, where the electrons are RF-accelerated to 1-4 MeV. A focusing channel having a plurality of annular permanent magnets can surround the dielectric tube, and a vacuum can be maintained in the tube by a getter pump. The accelerating RF can be 10 GHz or higher. The X-ray source can be powered by a rechargeable battery for more than an hour. Embodiments can be transported within a case having a display attached to an interior surface of its lid. An X-ray head can be removed from the case and extended up to 10 feet while remaining interconnected with the case by a flexible conduit.

Abstract: A salt of a quinazoline derivative (N-[4-(3-chlorine-4-fluoroanilino)]-7-(3-morpholinepropanol)-6-(2-fluoroacrylamide)-quinazoline, the structure thereof is as represented by formula I). Compared with a known quinazoline derivative, the salt of the quinazoline derivative has one or more improved properties and at least has better water solubility, wherein a citrate, a benzene sulfonate, and an ethanedisulphonate thereof further have better crystallinity and are not easy to absorb moisture.

Abstract: An electromagnetic mechanical pulser implements a transverse wave metallic comb stripline TWMCS kicker having inwardly opposing teeth that retards a phase velocity of an RF traveling wave to match the kinetic velocity of a continuous electron beam, causing the beam to oscillate before being chopped into pulses by an aperture. The RF phase velocity is substantially independent of RF frequency and amplitude, thereby enabling independent tuning of the electron pulse widths and repetition rate. The TWMCS further comprises an electron pulse picker (EPP) that applies a pulsed transverse electric field across the TWMCS to deflect electrons out of the beam, allowing only selected electrons and/or groups of electrons to pass through. The EPP pulses can be synchronized with the RF traveling wave and/or with a pumping trigger of a transverse electron microscope (TEM), for example to obtain dynamic TEM images in real time.

Abstract: An electromagnetic mechanical pulser implements a transverse wave metallic comb stripline TWMCS kicker having inwardly opposing teeth that retards a phase velocity of an RF traveling wave to match the kinetic velocity of a continuous electron beam, causing the beam to oscillate before being chopped into pulses by an aperture. The RF phase velocity is substantially independent of RF frequency and amplitude, thereby enabling independent tuning of the electron pulse widths and repetition rate. The TWMCS further comprises an electron pulse picker (EPP) that applies a pulsed transverse electric field across the TWMCS to deflect electrons out of the beam, allowing only selected electrons and/or groups of electrons to pass through. The EPP pulses can be synchronized with the RF traveling wave and/or with a pumping trigger of a transverse electron microscope (TEM), for example to obtain dynamic TEM images in real time.

Abstract: Disclosed are a battery charging control method and apparatus, and a battery powered device such as an electric vehicle. The method, for each cell in at least one cell of a multi-cell battery, includes: after the multi-cell battery enters a charging stable state, acquiring actual charging electric quantity required for charging the cell to a target voltage; determining a balance time duration for the cell based on the actual charging electric quantity corresponding to the cell, wherein the balance time duration is a time duration required for a cell balance control circuit matched with the cell to control the cell; and controlling the cell balance control circuit matched with the cell to perform electric quantity adjustment on the cell within the balance time duration. The technical problem of low accuracy of balance control on each cell in the multi-cell battery in the related art is solved.

Abstract: In embodiments, a linac electron beam excited X-ray source weighing less than 50 pounds, and having a volume less than 1 cubic foot, injects electrons from an RF-excited, diamond tip cathode into a dielectric accelerator tube of diameter less than 10 mm, where the electrons are RF-accelerated to 1-4 MeV. A focusing channel having a plurality of annular permanent magnets can surround the dielectric tube, and a vacuum can be maintained in the tube by a getter pump. The accelerating RF can be 10 GHz or higher. The X-ray source can be powered by a rechargeable battery for more than an hour. Embodiments can be transported within a case having a display attached to an interior surface of its lid. An X-ray head can be removed from the case and extended up to 10 feet while remaining interconnected with the case by a flexible conduit.

Abstract: A nucleic acid probe and a nucleic acid sequencing method for performing sequencing while ligating nucleic acids. The nucleic acid probe is a DNA sequencing probe, comprising a first moiety, a second moiety, a linker, and a detectable label. A base of the first moiety is A, T, U, C, or G, a base of the second moiety is a random base and/or a universal base, and 3 bases or more are present in the second moiety. The first moiety and the second moiety are ligated via the linker, the connection between the first moiety and the ligation can be cleaved, and the detectable label is ligated to the second moiety or the linker. The above probe, a combination formed therewith, or a sequencing method using the same can reduce the number or types of probes in nucleic acid sequencing, thereby reducing cost.

Abstract: Embodiments of the present disclosure disclose a method and apparatus for determining a topic. A specific embodiment of the method comprises: determining a to-be-recognized sentence sequence; calculating similarities between the to-be-recognized sentence sequence and each of topic templates in a topic template set in a target area, the each of the topic templates in the topic template set corresponding to a topic in at least one topic in the target area, the topic template including a topic section sequence, and a topic section including a topic sentence sequence; and determining a topic of the to-be-recognized sentence sequence according to an associated parameter, the associated parameter including the similarities between the to-be-recognized sentence sequence and the each of the topic templates in the topic template set. This embodiment reduces labor costs during a topic segmentation.

Abstract: The present invention discloses a performance prediction method and system of pervious concrete based on a meso-structure reconstruction model.

Abstract: A method for processing an asynchronous event by a checking device and a checking device are provided, the method including: obtaining an instruction position where a checked processor executes an asynchronous event during a target running process; and executing the asynchronous event at the instruction position during executing a task of the target running process in a manner conforming to predefined behavior, wherein the predefined behavior is a hardware behavior standard of the processor. Obtaining the instruction position and executing the asynchronous event at the instruction position may cause the checking device and the checked processor to process the same asynchronous event at the same instruction position. In this way, during performing security checking on a processor, the method and the device according to the embodiments of the present disclosure may be used to eliminate the influence of the uncertainty factor of the asynchronous event.

Abstract: The present disclosure provides technical solutions related to action undo service based on cloud platform. Related operations dependent on target operations to be undone may be obtained by dependency analysis and the target operations and the related operations may be undone by time sequence so as to reduce the conflict caused by the undo operations.

Abstract: The disclosure provides an input and output recording device and method, CPU and data read and write operation method thereof. The input and output recording device is provided between a central processor CPU and a peripheral, and is configured to record data read and write operations between the CPU and the peripheral, wherein the data read and write operations comprise a data read and write operation initiated by the peripheral and a data read and write operation initiated by the CPU; the input and output recording device is further configured to request the CPU to process the data read and write operation initiated by the peripheral, and upon receiving an instruction sent by the CPU, send a data packet of the data read and write operation initiated by the peripheral to the CPU.

Abstract: An inhibitor of a wild type and Y641F mutant of human histone methyltransferase EZH2 is provided herein. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat a cancer or precancerous condition related to EZH2 activity.

Abstract: A checking method for a processor is provided. The checking method first determines whether a checked processor satisfies a security-sensitive condition including one or more of security-sensitive instruction, processor running mode, security-sensitive input/output operation, security-sensitive application, and user-defined security level. Then, the checking method checks the checked processor according to a determination result, which further includes: when the checked processor satisfies the security-sensitive condition, checking the checked processor according to a first checking mode; and when the checked processor does not satisfy the security-sensitive condition, checking the checked processor according to a second checking mode; wherein for the same running process of the checked processor, a total checking length of the first checking mode is longer than that of the second checking mode. Also provided is a checking device for a processor and a checking system for a processor.

Abstract: The present disclosure discloses a processor security checking method, system and checking device. The processor security checking method includes: acquiring recording information of data read and write operations between a processor and a peripheral device, where the data read and write operation is a data read and write operation initiated by the processor or a data read and write operation initiated by the peripheral; and determining whether the processor is secure according to the recording information of the data read and write operation and an analysis result on the data read and write operation by the checking device. The embodiments of the present disclosure may detect hardware vulnerabilities and improve the security of hardware usage.

Abstract: An aerothermal-radiation correction method, including: using a Gaussian surface to approximate a thermal radiation noise, performing a Fourier transform on the Gaussian surface so as to obtain a centralized spectrum of the thermal radiation noise, constructing a filter function H based on the centralized spectrum of the thermal radiation noise; performing a Fourier transform on the aerothermal-radiation degraded image f so as to obtain a centralized spectrum F, taking dot product of F and H to obtain a filtered spectrum G; and performing an inverse Fourier transform on filtered spectrum G to obtain a modulus, and acquire a corrected image. The method effectively removes background noise generated by aerothermal radiation, greatly improves image quality and image signal-to-noise ratio. The method features reduced computational complexity and a shorter operation time, and is suited for real-time processing.

Abstract: An electromagnetic mechanical pulser implements a transverse wave metallic comb stripline TWMCS kicker having inwardly opposing teeth structured to retard a phase velocity of an RF traveling wave propagated therethrough to match the kinetic velocity of a continuous electron beam simultaneously propagated therethrough. The kicker imposes transverse oscillations onto the beam, which is subsequently chopped into pulses by an aperture. The RF phase velocity is substantially independent of RF frequency and amplitude, thereby enabling independent tuning of the electron pulse widths and repetition rate. The exterior surface of the kicker is conductive, thereby avoiding electron charging. In embodiments, various elements of the kicker and/or aperture can be mechanically varied to provide further tuning of the pulsed electron beam. A divergence suppression section can include a mirror TWMCS and/or magnetic quadrupoles.

Abstract: An inhibitor of a wild type and Y641 F mutant of human histone methyltransferase EZH2 is provided herein. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat a cancer or precancerous condition related to EZH2 activity.

Abstract: The present disclosure discloses a subject matter message notification method performed at a terminal and to be disseminated to one or more target users. The method includes: displaying a subject matter editing interface, the subject matter editing interface including an editing item used for editing subject matter content, an editing item used for adding a target user, and an editing item used for adding a file; generating a subject matter message in accordance with user-provided subject matter content through the editing item used for editing subject matter content, one or more user-selected target users through the editing item used for adding a target user, and one or more user-selected files through the editing item used for adding a file; and sending the subject matter message to a server, wherein the server is configured to send the subject matter message to the one or more user-selected target users.