Patents by Inventor Ao Zhang

Ao Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240256872
    Abstract: A blockchain-based AI model training method is provided, comprising: building an original AI model according to features of data sets; randomly allocating participants in a training process proportionally into three categories: a model trainer, a model verifier and a model uploader, prior to start of each round of training of the original AI model; during each round of training, generating, by the model trainer and the model verifier, respective partial models of a current round; checking, by the model verifier, partial models generated by the model trainer through using partial models generated locally; aggregating, by the model uploader, all partial models passing the checking of the model verifier to obtain a global model of the current round, and packing the global model, checking results and all the partial models of the current round into a blockchain.
    Type: Application
    Filed: November 29, 2022
    Publication date: August 1, 2024
    Inventors: Yiying ZHANG, Yingzhuo LI, Ao ZHANG, Cong WANG, Kun LIANG, Xiankun ZHANG
  • Patent number: 12038955
    Abstract: The disclosure provides a method for generating a query statement. The method includes: determining a first vector representation based on known nodes in a first syntax tree corresponding to a query statement to be generated; determining a target generation strategy corresponding to a target node to be generated based on the first vector representation and a preset copy reference matrix; generating the target node based on the first vector representation or a second vector representation by performing the target generation strategy, in which the second vector representation is a vector representation corresponding to an adjacent query statement prior to the query statement to be generated; and generating the query statement based on the known nodes and a terminator in response to the target node being the terminator.
    Type: Grant
    Filed: February 24, 2022
    Date of Patent: July 16, 2024
    Assignee: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Ao Zhang, Lijie Wang, Xinyan Xiao, Tingting Li
  • Patent number: 11834432
    Abstract: Provided in the present invention are a substituted amino six-membered nitric heterocyclic ring compound and a preparation and use thereof. In particular, provided in the present invention is a compound as shown by general formula (I) below, wherein the definition of each group is as described in the description. The compound of the present invention has an excellent tyrosine kinase inhibitory activity, and can thus be used to prepare a series of medicines for treating diseases related to tyrosine kinase inhibitory activity.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: December 5, 2023
    Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Ao Zhang, Meiyu Geng, Li Xing, Jing Ai, Zilan Song, Xia Peng, Wangting Gu, Jian Ding
  • Publication number: 20230285389
    Abstract: Use of a compound of general formula (A) which is a CFS-1R kinase inhibitor or a pharmaceutically acceptable salt thereof in the preparation of medicaments for treating diseases related to CSF-1R kinase signal transduction pathway or medicaments for regulating immunization. In vivo and in vitro studies show that the compound can significantly inhibit CSF-1R kinase activity; significantly inhibits the proliferation of a CSF-1/CSF-1R-driven mouse myeloid leukemia cell line, inhibits the survival of macrophages induced by CSF-1 and reverses M2 polarization phenotype of macrophages, and has an effect superior to that of the marketed medicament Pexidartinib. In a TAM enriched tumor model (MC38 model), the compound significantly antagonizes the tumor immunosuppressive microenvironment and exhibits significant anti-tumor efficacy.
    Type: Application
    Filed: February 26, 2021
    Publication date: September 14, 2023
    Inventors: Ao ZHANG, Meiyu GENG, Jing AI, Caixia WANG, Xia PENG, Yang ZHANG, Jian DING
  • Patent number: 11748340
    Abstract: The present disclosure provides a data pair generating method, apparatus, electronic device and storage medium, and the field of artificial intelligence such as natural language processing and deep learning. The method may include: generating M SQL query statements for a given database, where M is a positive integer greater than one; performing the following processing for each SQL query statement: dividing the SQL query statement into at least one SQL clause; obtaining a question description corresponding to each SQL clause; combining the question descriptions to obtain a question corresponding to the SQL query statement. The solution of the present disclosure may be applied to save manpower and time costs.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: September 5, 2023
    Assignee: BEIJING BAIDU NETCOM SCIENCE AND TECHNOLOGY CO., LTD.
    Inventors: Lijie Wang, Ao Zhang
  • Publication number: 20230244362
    Abstract: A display method, apparatus, device and storage medium, the method includes: displaying a user interface for playing a target video (S101), where the user interface includes an image display area, and the target video includes multiple target sub-videos; playing each target sub-video in the target video sequentially on the user interface while displaying multiple images in the image display area (S102), where the multiple target sub-videos respectively correspond to the multiple images displayed in the image display area; and in response to a first triggering operation acting on a target image in the image display area, jumping to and displaying target information associated with the target image (S103), where the target image includes any image displayed in the image display area. The method can provide users with convenient operations to realize multi-functionalization, thereby meeting their needs and enhancing their operational experience.
    Type: Application
    Filed: July 2, 2021
    Publication date: August 3, 2023
    Inventors: Ao ZHANG, Ji LIU, Shun LIU, Shengyan SHI, Shuhan XU, Ruihan WANG
  • Publication number: 20230210074
    Abstract: A method for organically planting Dendrobium, including using a planting medium in the epiphytic planting step of Dendrobium. The raw materials of planting medium include fermented powder of Dendrobium candidum leaves and sawdust; a method for preparing the fermented powder of Dendrobium candidum leaves is as follows: cutting Dendrobium candidum leaves into small pieces and mashing the small pieces of Dendrobium candidum leaves to obtain materials to be fermented, and then adding liquid medium to the materials to be fermented to obtain fermentation system; sterilizing the fermentation system, adding fermentation bacteria to the fermentation system to obtain a mixture, fermenting and filtering the mixture to obtain post-culturing fermentation broth and fermented products of Dendrobium candidum leaves, dewatering and crushing the fermented products of Dendrobium candidum leaves to obtain fermented powder of Dendrobium candidum leaves.
    Type: Application
    Filed: August 26, 2022
    Publication date: July 6, 2023
    Applicant: Southwest Forestry University
    Inventors: Xiahong He, Rui Shi, Shu He, Bingjie Xiong, Youguo Huang, Xingru Yan, Ao Zhang, Xixi Liang
  • Publication number: 20230210064
    Abstract: The present disclosure relates to the technical field of Gastrodia elata planting, in particular to an organic planting method of G. elata, including the process of mycelia colonized material preparation: cutting a branch of Quercus acutissima into bars; cutting out fish scale openings on the bars to obtain bars with the fish scale openings; successively soaking the bars with the fish scale openings in boiling water and a growth-promoting solution to obtain bars after growth promotion treatment; and putting Amillariella mellea spawns and an inoculation substrate into each fish scale opening of the bars after the growth promotion treatment to obtain a mycelia colonized material. The growth-promoting solution and the inoculation substrate are prepared by treatment of fresh G. elata stalks with Bacillus pumilus and hot-dip extraction treatment in ethanol.
    Type: Application
    Filed: September 6, 2022
    Publication date: July 6, 2023
    Applicant: Southwest Forestry University
    Inventors: Xiahong HE, Rui SHI, Shu HE, Bingjie XIONG, Youguo HUANG, Xingru YAN, Ao ZHANG, Xixi LIANG
  • Publication number: 20220235061
    Abstract: The present disclosure relates to triazolopyrimidine compounds and salts, compositions and uses thereof, and the triazolopyrimidine compounds have the structures represented by the formula (I): the above-mentioned triazolopyrimidine compounds have good activity and high selectivity for NAE.
    Type: Application
    Filed: June 12, 2020
    Publication date: July 28, 2022
    Inventors: Ao ZHANG, Zehong MIAO, Chaodong XIONG, Shanshan SONG, Jinxue HE
  • Publication number: 20220204518
    Abstract: The present invention relates to a pyrimido[5,4-b]pyrrolizin compound represented by general formula I, an optical isomer thereof, a preparation method therefor, a pharmaceutical composition containing same, and a use thereof. The compound according to the present invention has good inhibitory activity on the kinase BTK at both the molecular level and the cellular level. Meanwhile, the compound also has good anti-tumor activity and pharmacokinetic properties in vivo.
    Type: Application
    Filed: April 24, 2020
    Publication date: June 30, 2022
    Inventors: Ao ZHANG, Jian DING, Hua XIE, Zilan SONG, Yu XUE, Li XING, Linjiang TONG, Meiyu GENG
  • Patent number: 11366973
    Abstract: Embodiments of the present disclosure disclose a method and apparatus for determining a topic. A specific embodiment of the method comprises: determining a to-be-recognized sentence sequence; calculating similarities between the to-be-recognized sentence sequence and each of topic templates in a topic template set in a target area, the each of the topic templates in the topic template set corresponding to a topic in at least one topic in the target area, the topic template including a topic section sequence, and a topic section including a topic sentence sequence; and determining a topic of the to-be-recognized sentence sequence according to an associated parameter, the associated parameter including the similarities between the to-be-recognized sentence sequence and the each of the topic templates in the topic template set. This embodiment reduces labor costs during a topic segmentation.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: June 21, 2022
    Inventors: Jingwei Wang, Ao Zhang, Jiaxiang Liu, Yu Sun, Zhi Li
  • Publication number: 20220179889
    Abstract: The disclosure provides a method for generating a query statement. The method includes: determining a first vector representation based on known nodes in a first syntax tree corresponding to a query statement to be generated; determining a target generation strategy corresponding to a target node to be generated based on the first vector representation and a preset copy reference matrix; generating the target node based on the first vector representation or a second vector representation by performing the target generation strategy, in which the second vector representation is a vector representation corresponding to an adjacent query statement prior to the query statement to be generated; and generating the query statement based on the known nodes and a terminator in response to the target node being the terminator.
    Type: Application
    Filed: February 24, 2022
    Publication date: June 9, 2022
    Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Ao ZHANG, Lijie WANG, Xinyan XIAO, Tingting LI
  • Publication number: 20220179847
    Abstract: The present disclosure provides a data pair generating method, apparatus, electronic device and storage medium, and the field of artificial intelligence such as natural language processing and deep learning. The method may include: generating M SQL query statements for a given database, where M is a positive integer greater than one; performing the following processing for each SQL query statement: dividing the SQL query statement into at least one SQL clause; obtaining a question description corresponding to each SQL clause; combining the question descriptions to obtain a question corresponding to the SQL query statement. The solution of the present disclosure may be applied to save manpower and time costs.
    Type: Application
    Filed: July 23, 2021
    Publication date: June 9, 2022
    Applicant: BEIJING BAIDU NETCOM SCIENCE AND TECHNOLOGY CO., LTD.
    Inventors: Lijie WANG, Ao ZHANG
  • Publication number: 20220089561
    Abstract: A fluorine-containing substituted benzothiophene compound and a pharmaceutical composition and an application thereof are described. The compound has the structure as shown in formula (I), in which the definitions of each group and substituent are as described in the description. A preparation method of the compound and an anti-tumor application thereof are also described.
    Type: Application
    Filed: December 31, 2019
    Publication date: March 24, 2022
    Inventors: Ao ZHANG, Meiyu GENG, Chunyong DING, Zuoquan XIE, Jian DING, Yan ZHANG, Ancheng SHEN, Xiyuan WANG
  • Patent number: 11191761
    Abstract: Disclosed is an SOMCL-9112 solid dispersion. The SOMCL-9112 solid dispersion is characterized by being prepared from the following raw materials in percentage by weight: 5 percent to 60 percent of SOMCL-9112, 5 percent to 90 percent of pharmaceutically acceptable matrix polymer, 0 percent to 20 percent of surfactant, 0 percent to 20 percent of flow aid and 0 percent to 20 percent of plasticizer. Also disclosed are a preparation method of the SOMCL-9112 solid dispersion, a solid medicinal preparation containing the solid dispersion and application of the solid dispersion for preparing a medicine for treating cancer.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: December 7, 2021
    Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SHANGHAI ACEBRIGHT PHARMACEUTICALS CO., LTD.
    Inventors: Shiyan Guo, Yong Gan, Ao Zhang, Zehong Miao, Li Gao, Jian Ding
  • Publication number: 20210342379
    Abstract: The disclosure discloses a method and a device for processing a sentence, and a storage medium. The detailed implementation includes: during processing a sentence, obtaining a dependency tree graph among respective segmented words in the sequence of segmented words by performing a dependency parsing on a sequence of segmented words of the sentence, inputting the dependency tree graph and a word vector corresponding to each segmented word into a preset graph neural network to obtain an intermediate word vector of each segmented word in the sequence of segmented words, and obtaining a processing result of the sentence by performing the downstream task on the intermediate word vector of each segmented word.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 4, 2021
    Inventors: Shuai ZHANG, Lijie WANG, Ao ZHANG, Xinyan XIAO, Yue CHANG
  • Patent number: D1023150
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: April 16, 2024
    Assignee: Shenzhen Konkr Technology Co., Ltd.
    Inventor: Ao Zhang
  • Patent number: D1023151
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: April 16, 2024
    Assignee: Shenzhen Konkr Technology Co., Ltd.
    Inventor: Ao Zhang
  • Patent number: D1039276
    Type: Grant
    Filed: September 21, 2023
    Date of Patent: August 20, 2024
    Inventor: Ao Zhang
  • Patent number: D1069909
    Type: Grant
    Filed: October 25, 2022
    Date of Patent: April 8, 2025
    Assignee: Shenzhen Konkr Technology Co., Ltd.
    Inventor: Ao Zhang