Abstract: A catheter includes elongate flexible inner and outer tubular lumens having proximal and distal regions, and a plurality of exit markers formed in the proximal region. The inner tubular lumen includes an outer surface, and an inner surface, the inner surface defining a guidewire passageway. The outer tubular lumen includes an elongate, flexible, and substantially transparent outer tubular lumen having an outer surface, and an inner surface surrounding the inner tubular lumen. The exit markers may be formed on the inner tubular lumen outer surface or on the outer tubular lumen inner surface, the exit markers being visible to the naked eye through the substantially transparent outer tubular lumen outer surface. The exit markers may also be integrally formed from a polymer that forms a portion of the proximal region of the outer tubular lumen or the inner tubular lumen.