Abstract: A chromatograph and a method of acquiring and displaying a real-time chromatogram using time-stamped asynchronous messaging are provided. The method includes generating a chromatogram of a sample, acquiring segments of data points of the chromatogram in real-time, annotating in real-time the segments of data points of the chromatogram with timing stamps of cycle events of an analysis cycle using time-stamped event messages, receiving the time-stamped event messages asynchronously and displaying each cycle event of the cycle events of the analysis cycle and each segment of the segments of data points of the chromatogram in a display module as being received.

Abstract: A chromatograph and a method of acquiring and displaying a real-time chromatogram using time-stamped asynchronous messaging are provided. The method includes generating a chromatogram of a sample, acquiring segments of data points of the chromatogram in real-time, annotating in real-time the segments of data points of the chromatogram with timing stamps of cycle events of an analysis cycle using time-stamped event messages, receiving the time-stamped event messages asynchronously and displaying each cycle event of the cycle events of the analysis cycle and each segment of the segments of data points of the chromatogram in a display module as being received.

Abstract: A thermal conductivity detector includes a switch controllable to short-circuit the input of an amplifier to improve the thermal conductivity detector for use in gas chromatography without the need of an additional reference cell, wherein a digital signal processor calculates a transfer function of an analog signal processor from a digitized difference signal received in response to short-circuiting the input of the amplifier at a given time when solely a reference carrier fluid passes through a measuring cell, and the digital signal processor recovers a detector signal by deconvoluting the digitized difference signal with a transfer function.

Abstract: A gas chromatograph in which components of a sample of a gas mixture are separated via a separation column, a sensing element of a thermal conductivity detector is operated at a first temperature to detect separated components and to generate a detector signal in response to detected components, an evaluation unit evaluates detector signals and determines concentrations of detected components, a further sensing element of a further thermal conductivity detector is operated at a second temperature different from the first temperature, to detect gas components of widely different concentration ranges at high sensitivity, where the thermal conductivity detectors are calibrated for different concentration ranges, and the evaluation unit compares the detector signal with the detector signal of the further thermal conductivity detector to output a concentration value determined from the signal of the thermal conductivity detector calibrated for the measured component concentration.

Abstract: A thermal conductivity detector includes a switch controllable to short-circuit the input of an amplifier to improve the thermal conductivity detector for use in gas chromatography without the need of an additional reference cell, wherein a digital signal processor calculates a transfer function of an analog signal processor from a digitized difference signal received in response to short-circuiting the input of the amplifier at a given time when solely a reference carrier fluid passes through a measuring cell, and the digital signal processor recovers a detector signal by deconvoluting the digitized difference signal with a transfer function.

Abstract: A gas chromatograph in which components of a sample of a gas mixture are separated via a separation column, a sensing element of a thermal conductivity detector is operated at a first temperature to detect separated components and to generate a detector signal in response to detected components, an evaluation unit evaluates detector signals and determines concentrations of detected components, a further sensing element of a further thermal conductivity detector is operated at a second temperature different from the first temperature, to detect gas components of widely different concentration ranges at high sensitivity, where the thermal conductivity detectors are calibrated for different concentration ranges, and the evaluation unit compares the detector signal with the detector signal of the further thermal conductivity detector to output a concentration value determined from the signal of the thermal conductivity detector calibrated for the measured component concentration.

Abstract: A method for quantifying peaks in an analytical signal, peaks in the analytical signal being quantified by recording successive signal values and applying a peak analysis methodology to the recorded successive signal values within an interval to obtain a set of peak quantification results. Before the same peak analysis methodology is applied to the modified signal to quantify the peaks in the signal, random noise is added to the analytical signal and/or the signal is shifted within the interval to facilitate optimization of the parameters of the peak analysis methodology and to improve the robustness of the method in runtime applications. A subsequent statistical evaluation of the peak quantification results from the multiple repeated peak analyses of the original and modified signals is used to detect an occurrence of and to reduce the chance of a possible error in the peak quantification that needs to be alarmed or addressed.

Abstract: A gas chromatograph comprising a separation column for separating components of a sample of a gas mixture fed through the separation column by a carrier gas, a thermal conductivity detector including a sensing element arranged downstream from the separation column and configured to detect the separated components in a non-destructive manner and to generate a detector signal in response the detected components, an evaluation unit for evaluating the detector signals to determine concentrations of the detected components, and a further thermal conductivity detector including a further sensing element arranged immediately downstream or upstream from the thermal conductivity detector and configured to detect the separated components and to generate a further detector signal in response to the detected components, where the evaluation unit is configured to compare the detector signal with the further detector signal to recognize and signal a loss of or improper detection by the thermal conductivity detector.

Abstract: The invention relates to a method for processing chromatograms obtained by a process gas chromatograph in a plurality of subsequent measurements of a process stream.

Abstract: A method for quantifying peaks in an analytical signal, peaks in the analytical signal being quantified by recording successive signal values and applying a peak analysis methodology to the recorded successive signal values within an interval to obtain a set of peak quantification results. Before the same peak analysis methodology is applied to the modified signal to quantify the peaks in the signal, random noise is added to the analytical signal and/or the signal is shifted within the interval to facilitate optimization of the parameters of the peak analysis methodology and to improve the robustness of the method in runtime applications. A subsequent statistical evaluation of the peak quantification results from the multiple repeated peak analyses of the original and modified signals is used to detect an occurrence of and to reduce the chance of a possible error in the peak quantification that needs to be alarmed or addressed.