Patents by Inventor Aparajita Sarkar

Aparajita Sarkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Patent number: 7453011
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: November 18, 2008
    Assignee: Progen Pharmaceuticals, Inc.
    Inventors: Linda Clifford, legal representative, Aldonia L. Valasinas, Andrei V. Blokhin, Aparajita Sarkar, Hirak S. Basu, Venodhar K. Reddy, Laurence J. Marton, Yu Wang, Benjamin Frydman
  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Publication number: 20070287754
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Application
    Filed: June 4, 2007
    Publication date: December 13, 2007
    Inventors: Benjamin Frydman, Linda Clifford, Aldonia Valasinas, Andrei Blokhin, Aparajita Sarkar, Hirak Basu, Venodhar Reddy, Laurence Marton, Yu Wang
  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Patent number: 7235695
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Grant
    Filed: August 16, 2005
    Date of Patent: June 26, 2007
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Andrei V. Blokhin, Aparajita Sarkar, Hirak S. Basu, Venodhar K. Reddy, Laurence J. Marton, Yu Wang
  • Porphyrin-polyamine conjugates for cancer therapy
    Publication number: 20060276444
    Abstract: Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conjugate compounds are also disclosed.
    Type: Application
    Filed: February 7, 2006
    Publication date: December 7, 2006
    Inventors: Benjamin Frydman, Linda Clifford, Aldonia Valasinas, Venodhar Reddy, Hirak Basu, Aparajita Sarkar, Subhra Bhattacharya, Yu Wang, Laurence Marton, Andrei Blokhin
  • Porphyrin-polyamine conjugates for cancer therapy
    Patent number: 7026347
    Abstract: Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conjugate compounds are also disclosed.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: April 11, 2006
    Assignee: CellGate, Inc.
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Venodhar K. Reddy, Hirak S. Basu, Aparajita Sarkar, Subhra Bhattacharya, Yu Wang, Laurence J. Marton, Andrei V. Blokhin
  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Publication number: 20060030735
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Application
    Filed: August 16, 2005
    Publication date: February 9, 2006
    Applicant: CellGate, Inc.
    Inventors: Benjamin Frydman, Linda Clifford, Aldonia Valasinas, Andrei Blokhin, Aparajita Sarkar, Hirak Basu, Venodhar Reddy, Laurence Marton, Yu Wang
  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Patent number: 6982351
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: January 3, 2006
    Assignee: CellGate, Inc.
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Andrei V. Blokhin, Aparajita Sarkar, Hirak S. Basu, Venodhar K. Reddy, Laurence J. Marton, Yu Wang
  • Porphyrin-polyamine conjugates for cancer therapy
    Publication number: 20040152687
    Abstract: Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conjugate compounds are also disclosed.
    Type: Application
    Filed: June 24, 2003
    Publication date: August 5, 2004
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Venodhar K. Reddy, Hirak S. Basu, Aparajita Sarkar, Subhra Bhattacharya, Yu Wang, Laurence J. Marton, Andrei V. Blokhin
  • Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
    Publication number: 20030195377
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Application
    Filed: December 6, 2002
    Publication date: October 16, 2003
    Applicant: SLIL Biomedical Corporation
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Andrei V. Blokhin, Aparajita Sarkar, Hirak S. Basu, Venodhar K. Reddy, Laurence J. Marton, Yu Wang