Patents by Inventor Apostolos Kyriatsoulis

Apostolos Kyriatsoulis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Release reagent for vitamin D compounds
    Patent number: 9341552
    Abstract: The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analyzed, the use of the reagent to release vitamin D compounds as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunological reagents.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: May 17, 2016
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Apostolos Kyriatsoulis, Susanne Feldmann, Eramus Huber, Nicole Horn, Leopold von Proff, Uwe Kobold, Angela Puhlmann
  • RELEASE REAGENT FOR VITAMIN D COMPOUNDS
    Publication number: 20150104876
    Abstract: The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analyzed, the use of the reagent to release vitamin D compounds as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunological reagents.
    Type: Application
    Filed: December 18, 2014
    Publication date: April 16, 2015
    Inventors: Apostolos Kyriatsoulis, Susanne Feldmann, Eramus Huber, Nicole Horn, Leopold von Proff, Uwe Kobold, Angela Puhlmann
  • RELEASE REAGENT FOR VITAMIN D COMPOUNDS
    Publication number: 20090093445
    Abstract: The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analyzed, the use of the reagent to release vitamin D compounds as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunological reagents.
    Type: Application
    Filed: March 24, 2008
    Publication date: April 9, 2009
    Inventors: Apostolos Kyriatsoulis, Susanne Feldmann, Eramus Huber, Nicole Horn, Leopold von Proff
  • ANTIBODIES AGAINST 25-HYDROXYVITAMIN D
    Publication number: 20080317764
    Abstract: The present invention concerns processes for producing antibodies against 25-hydroxyvitamin D, the antibodies produced according to the invention as well as methods for the detection of 25-hydroxyvitamin D using these antibodies.
    Type: Application
    Filed: March 21, 2008
    Publication date: December 25, 2008
    Inventors: Eramus Huber, Juergen Becker, Nicole Horn, Apostolos Kyriatsoulis, Werner Kraus, Rudolf Vogel
  • Stabilization of calibrators containing cytokeratin
    Patent number: 6635485
    Abstract: The invention concerns calibrators or calibration solutions which are based on a human serum matrix and which are used in a method for detecting cytokeratin, a process for producing them, a method for stabilizing cytokeratin and an immunological method for detecting cytokeratin in a sample.
    Type: Grant
    Filed: October 27, 2001
    Date of Patent: October 21, 2003
    Assignee: Roche Diagnostics GmbH
    Inventors: Apostolos Kyriatsoulis, Gunter Pappert, Ellen Moessner, Norbert Franken, Michael Rottmann, Heinz Bodenmueller