Patents by Inventor Appi Reddy MANDHAPATI

Appi Reddy MANDHAPATI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neomycin and paromomycin derivatives
    Patent number: 11466044
    Abstract: The present disclosure relates to derivatives of neamine-based aminoglycoside antibacterial drugs modified in position C6?, C2? and/or C5?. The modifications impart favorable properties regarding activity against ESKAPE pathogens, evasion of resistance traits and increased selectivity, enabling systemic use of the compounds.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: October 11, 2022
    Assignees: WAYNE STATE UNIVERSITY, UNIVERSITAT ZURICH
    Inventors: David Crich, Girish Sati, Amr Sonousi, Guanyu Yang, Appi Reddy Mandhapati, Michael G. Pirrone, Takayuki Kato, Vikram Sarpe, Andrea Vasella, Erik C. Bottger, Sven N. Hobbie
  • NEOMYCIN AND PAROMOMYCIN DERIVATIVES
    Publication number: 20210107932
    Abstract: The present disclosure relates to derivatives of neamine-based aminoglycoside antibacterial drugs modified in position C6?, C2? and/or C5?. The modifications impart favorable properties regarding activity against ESKAPE pathogens, evasion of resistance traits and increased selectivity, enabling systemic use of the compounds.
    Type: Application
    Filed: April 6, 2018
    Publication date: April 15, 2021
    Applicants: WAYNE STATE UNIVERSITY, UNIVERSITAT ZURICH
    Inventors: David CRICH, Girish SATI, Amr SONOUSI, Guanyu YANG, Appi Reddy MANDHAPATI, Michael G. PIRRONE, Takayuki KATO, Vikram SARPE, Andrea VASELLA, Erik C. BOTTGER, Sven N. HOBBIE