Patents by Inventor April Cunningham

April Cunningham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphatase inhibitors and methods of use thereof
    Patent number: 6040323
    Abstract: The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: March 21, 2000
    Assignee: University of Pittsburgh
    Inventors: John S. Lazo, Robert L. Rice, April Cunningham, Peter Wipf
  • Phosphatase inhibitors and methods of use thereof
    Patent number: 5925660
    Abstract: The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: July 20, 1999
    Assignee: University of Pittsburgh
    Inventors: John S. Lazo, Robert L. Rice, April Cunningham, Peter Wipf
  • Phosphatase inhibitors and methods of use thereof
    Patent number: 5856506
    Abstract: The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: January 5, 1999
    Assignee: University of Pittsburgh
    Inventors: John S. Lazo, Robert L. Rice, April Cunningham, Peter Wipf
  • Phosphatase inhibitors and methods of use thereof
    Patent number: 5700821
    Abstract: The present invention is directed to compounds having the formula: ##STR1## The invention further provides a method of making the compounds. The compounds are useful as inhibitors of protein phosphatases, for example PP1, PP2A, PP3, CDC25A and CDC25B. The invention is further directed to a method of inhibiting a protein phosphatase, a method of inhibiting cell proliferation, and pharmaceutical compositions comprising the subject compounds.
    Type: Grant
    Filed: July 30, 1996
    Date of Patent: December 23, 1997
    Assignee: University of Pittsburgh
    Inventors: John S. Lazo, Robert L. Rice, April Cunningham, Peter Wipf