Abstract: A recombinant adeno-associated virus (rAAV) vector comprising an AAVhu68 capsid produced in a production system comprising a nucleotide sequence of SEQ ID NO: 1, or a sequence at least 75% identical thereto which encodes SEQ ID NO:2. The AAVhu68 capsid comprises subpopulations of highly deamidated asparagine residues in asparagine-glycine pairs in the amino acid sequence of SEQ ID NO: 2. Also provided are compositions containing the rAAV and uses thereof. Additionally, rAAV having an engineered AAV capsid comprising at least one subpopulation of vp1 or vp2 proteins having a Val at amino acid position 157 with reference to the AAVhu68 vp1 numbering are provided.

Abstract: Notifications used to notify called parties of missed calls can vary based on priority levels of the missed calls. Priority levels can be assigned using characteristics of the missed call, such as a calling number/party associated with the missed call, a number of missed calls received from the calling number/party, whether or not the calling party left a voicemail, a time the missed call was received, or combinations thereof. Different notification levels may be associated with different priority levels, with each notification level specifying different alert setting parameters, e.g., different sounds/volumes, visual notifications, vibration settings, etc. Some notification levels may override a silent mode of the mobile device, while other notifications levels may not. Priority levels can be escalated when users fail to acknowledge a notification prior to expiration of a timer or when notification attempts are unsuccessful.

Abstract: Users can be alerted of important missed calls while away from their mobile device by sending missed call notifications to contacts of the user, which may include friends, family, colleagues, or other people/entities associated with the called party. The missed call notifications may include text or automated voicemail messages, email messages, and/or messages sent via a social networking site or service to name a few, and can specify information pertaining to the missed call and/or the calling party. Missed call notifications can be triggered when one or more predefined conditions are met, such as when the mobile device is deemed not to be in the possession of the user and/or the missed call is deemed to be important. Missed call notifications can originate from the mobile device or a network device.