Patents by Inventor Apurva Kumar Srivastava

Apurva Kumar Srivastava has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220074944
    Abstract: Immunoassays to detect the presence of Bcl-2 family heterodimeric complexes are described. The immunoassays are designed to detect one or more of BIM-Bcl-2, BIM-Bcl-xL, BIM-Mcl-1 and BAX-BAK heterodimers. The assays can be used, for example, to select a BH3 mimetic, or other drug targeting the apoptosis pathway, that is effective for treating a specific cancer, or to select a subject who is likely to respond to a particular BH3 mimetic.
    Type: Application
    Filed: January 29, 2020
    Publication date: March 10, 2022
    Applicant: The United States of America, as Represented by the Secretary,Department of Health and Human Service
    Inventors: Apurva Kumar Srivastava, Dominic Esposito, Jeevan Prasaad Govindharajulu, Ralph Ewin Parchment, James Halpern Doroshow