Patents by Inventor Araz Raoof

Araz Raoof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense permeation enhancers
    Patent number: 8039444
    Abstract: A pharmaceutical composition comprising an antisense oligonucleotide and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: October 18, 2011
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Araz A. Raoof, Mangaraju Gudipati, David C. Bibby, Susan Weinbach
  • Permeation enhancers
    Patent number: 7820722
    Abstract: A pharmaceutical composition comprising a drug and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: October 26, 2010
    Assignee: Merrion Research III Limited
    Inventors: Araz A. Raoof, Mangaraju Gudipati
  • Nanoparticulate insulin
    Publication number: 20070122486
    Abstract: Nanoparticulate insulin compositions having effective an average particle size of less than about 5 microns are described. The compositions exhibit retention of insulin bioactivity, increased bioavailability, and increased consistency of bioavailability as compared to prior macro-sized insulin compositions. Methods of making nanoparticulate insulin compositions, dosage forms containing them, and the use of such formulations in insulin therapy are also described.
    Type: Application
    Filed: January 26, 2007
    Publication date: May 31, 2007
    Inventors: Simon McGurk, Elaine Liversidge, Daniel O'Mahoney, Amy Weiderhold, Araz Raoof
  • Antisense permeation enhancers
    Publication number: 20070004668
    Abstract: A pharmaceutical composition comprising an antisense oligonucleotide and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.
    Type: Application
    Filed: August 23, 2006
    Publication date: January 4, 2007
    Inventors: Araz Raoof, Mangaraju Gudipati, David Bibby, Susan Reingold
  • Antisense permeation enhancers
    Publication number: 20030176379
    Abstract: A pharmaceutical composition comprising an antisense oligonucleotide and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.
    Type: Application
    Filed: May 13, 2002
    Publication date: September 18, 2003
    Inventors: Araz A. Raoof, Mangaraju Gudipati, David C. Bibby, Susan Weinbach Reingold
  • Nanoparticulate insulin
    Publication number: 20030095928
    Abstract: Nanoparticulate insulin compositions having effective an average particle size of less than about 5 microns are described. The compositions exhibit retention of insulin bioactivity, increased bioavailability, and increased consistency of bioavailability as compared to prior macro-sized insulin compositions. Methods of making nanoparticulate insulin compositions, dosage forms containing them, and the use of such formulations in insulin therapy are also described.
    Type: Application
    Filed: September 19, 2002
    Publication date: May 22, 2003
    Applicant: Elan Pharma International Limited
    Inventors: Simon McGurk, Elaine Liversidge, Daniel O'Mahoney, Amy Weiderhold, Araz Raoof
  • Permeation enhancers
    Publication number: 20030036568
    Abstract: A pharmaceutical composition comprising a drug and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.
    Type: Application
    Filed: May 13, 2002
    Publication date: February 20, 2003
    Inventors: Araz A. Raoof, Mangaraju Gudipati
  • Isostearic acid salts as permeation enhancers
    Publication number: 20030018085
    Abstract: A pharmaceutical composition comprising a drug and a permeation enhancer that comprises a mixture of compounds, said mixture containing a major amount of compound having a multi-carbon backbone having a partially or completely neutralized acid functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.
    Type: Application
    Filed: May 13, 2002
    Publication date: January 23, 2003
    Inventors: Araz A. Raoof, Mangaraju Gudipati