Patents by Inventor Archana V. Boopathy

Archana V. Boopathy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250049908
    Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
    Type: Application
    Filed: June 14, 2024
    Publication date: February 13, 2025
    Inventors: Jiani Li, Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Sarah Schmidt, Hesham Shehata, Felix Stemeseder, Evguenia Svarovskaia, Archana V. Boopathy
  • Publication number: 20220339416
    Abstract: Microneedle and microneedle devices including, e.g., silk fibroin-based microneedles tips for sustained dermal delivery of an anti-cancer agent and/or an immunomodulatory agent, as well as methods of manufacturing and using the same are described herein. In other embodiments, compositions and methods for burst-release or sustained-release administration of an anti-cancer agent and/or an immunomodulatory agent to provide an improved immune response to a cancer in a subject are described.
    Type: Application
    Filed: April 5, 2022
    Publication date: October 27, 2022
    Applicant: VAXESS TECHNOLOGIES, INC.
    Inventors: Kathryn M. Kosuda, Kimberly M. Cirelli, Alexander Beliveau, Archana V. Boopathy, Matthew Dirckx, Jonathan A. Kluge, Michael A. Schrader, Megan Eisele
  • Publication number: 20220218813
    Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 14, 2022
    Inventors: Jiani Li, Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Sarah Schmidt, Hesham Shehata, Felix Stemeseder, Evguenia Svarovskaia, Archana V. Boopathy
  • Publication number: 20210085598
    Abstract: Microneedle and microneedle devices including implantable silk-based tips for sustained dermal delivery of a vaccine, kits, as well as methods of manufacturing and using the same are described herein. In other embodiments, compositions and methods for controlled- or sustained-administration of a vaccine (e.g., an influenza vaccine) to provide improved immunogenicity and/or broad-spectrum immunity to a subject are also described.
    Type: Application
    Filed: April 2, 2019
    Publication date: March 25, 2021
    Inventors: Kathryn M. Kosuda, Jordan A. Stinson, Archana V. Boopathy, Matthew Dirckx, Jonathan A. Kluge, Yichen Zhang, Carter R. Palmer, Michael A. Schrader
  • Patent number: 9840693
    Abstract: This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain embodiments, the disclosure relates to compositions comprising a recombinant polypeptide comprising a cell signaling sequence, e.g., JAG-1 sequence, fused to a hydrogel polypeptide sequence. In certain embodiments, the disclosure relates to methods of cell culture on three dimensional scaffolds/hydrogels composed of self-assembling peptides disclosed herein.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: December 12, 2017
    Assignees: Emory University, Georgia Tech Research Corporation
    Inventors: Michael E. Davis, Archana V. Boopathy
  • Publication number: 20170137785
    Abstract: This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain embodiments, the disclosure relates to compositions comprising a recombinant polypeptide comprising a cell signaling sequence, e.g., JAG-1 sequence, fused to a hydrogel polypeptide sequence. In certain embodiments, the disclosure relates to methods of cell culture on three dimensional scaffolds/hydrogels composed of self-assembling peptides disclosed herein.
    Type: Application
    Filed: January 20, 2017
    Publication date: May 18, 2017
    Inventors: Michael E. Davis, Archana V. Boopathy
  • Patent number: 9585915
    Abstract: This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain embodiments, the disclosure relates to compositions comprising a recombinant polypeptide comprising a cell signaling sequence, e.g., JAG-1 sequence, fused to a hydrogel polypeptide sequence. In certain embodiments, the disclosure relates to methods of cell culture on three dimensional scaffolds/hydrogels composed of self-assembling peptides disclosed herein.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: March 7, 2017
    Assignees: Emory University, Georgia Tech Research Corporation
    Inventors: Michael E. Davis, Archana V. Boopathy
  • Publication number: 20150216906
    Abstract: This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain embodiments, the disclosure relates to compositions comprising a recombinant polypeptide comprising a cell signaling sequence, e.g., JAG-1 sequence, fused to a hydrogel polypeptide sequence. In certain embodiments, the disclosure relates to methods of cell culture on three dimensional scaffolds/hydrogels composed of self-assembling peptides disclosed herein.
    Type: Application
    Filed: January 22, 2015
    Publication date: August 6, 2015
    Inventors: Michael E. Davis, Archana V. Boopathy