Abstract: A method for translocating a cationic micro/nanoparticle across a mucus layer, the method including (a) contacting the mucus layer with at least one alginate oligomer, the alginate oligomer having at least 70% mannuronate residues, together with the cationic micro/nanoparticle; or (b)(i) contacting the cationic micro/nanoparticle with an alginate oligomer having at least 70% mannuronate residues thereby forming a micro/nanoparticle carrying the alginate oligomer, and (b)(ii) contacting the mucus layer with the micro/nanoparticle prepared in step (b)(i).

Abstract: The invention relates to a method for forming a dried absorbent foam having an open pore network and pores by preparing an aqueous dispersion comprising an enzymatically biodegradable biopolymer and a foaming agent and optionally one or more of gel-forming ions, a plasticizer, a crosslinking agent and a pH modifier, forming, preparing or mixing a foam from the aqueous dispersion and drying the foam to form a dried foam containing open pores. Gelled composites made from the foams are also provided. The invention is particularly useful in providing foams and composites for use in biomedical applications and as an anti-adhesive in tissue regeneration and wound management.