Abstract: The present invention relates to a method for differentiating mesenchymal stem cells into osteoblasts, a cell therapeutic agent for treating bone disease including osteoblasts differentiated by the method and a method for producing the same. In addition, the present invention relates to a method for treating bone disease, including the step of administering the osteoblasts obtained by the method to a patient with bone disease. The differentiation method according to the present invention can stably and rapidly differentiate mesenchymal stem cells into osteoblasts. The differentiated osteoblasts have excellent blood vessel-forming ability and excellent bone-forming ability. Accordingly, the method for differentiating stem cells into osteoblasts and the osteoblasts obtained by the method, according to the present invention, can be effectively used as a cell therapeutic agent or treatment method related to bone disease.

Abstract: A composition of a hyper-eutectic alloy related to the production of an intermolecular compound phase and primary Si. The hyper-eutectic alloy includes 1.0 to 3.0 wt % of copper (Cu), 0.1 to 0.3 wt % of magnesium (Mg), 13.5 to 15.5 wt % of silicon (Si), 0.1 wt % or less of nickel (Ni), and a balance of aluminum (Al). Thus, it is possible to have improved abrasion resistance as compared to ADC12 alloy and to have improved elongation and impact resistance as compared to K14 alloy.