Patents by Inventor Arezoo Modiri

Arezoo Modiri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR RADIATION THERAPY USING SPATIAL-FUNCTIONAL MAPPING AND DOSE SENSITIVITY OF BRANCHING STRUCTURES AND FUNCTIONAL SUB-VOLUMES
    Publication number: 20230181930
    Abstract: A method and apparatus for radiation therapy using functional measurements of branching structures. The method includes determining a location of each voxel of a plurality of voxels in a reference frame of a radiation device. The method further includes obtaining measurements that indicate a tissue type at each voxel. The method further includes determining a subset of the voxels based on an anatomical parameter of a respective branching structure of a set of branching structures indicated by the measurements. The method further includes determining a subset of the voxels that enclose an organ-at-risk (OAR) volume. The method further includes determining a value of a utility measure at each voxel. The method further includes determining a series of beam shapes and intensities which minimize a value of an objective function based on a computed dose delivered to each voxel and the utility measure for that voxel summed over all voxels.
    Type: Application
    Filed: February 7, 2023
    Publication date: June 15, 2023
    Inventors: Amit Sawant, Robert Timmerman, Yulong Yan, Henky Wibowo, Esther Vicente, Arezoo Modiri
  • System and method for radiation therapy using spatial-functional mapping and dose sensitivity of branching structures and functional sub-volumes
    Patent number: 11633623
    Abstract: A method and apparatus for radiation therapy using functional measurements of branching structures. The method includes determining a location of each voxel of a plurality of voxels in a reference frame of a radiation device. The method further includes obtaining measurements that indicate a tissue type at each voxel. The method further includes determining a subset of the voxels based on an anatomical parameter of a respective branching structure of a set of branching structures indicated by the measurements. The method further includes determining a subset of the voxels that enclose an organ-at-risk (OAR) volume. The method further includes determining a value of a utility measure at each voxel. The method further includes determining a series of beam shapes and intensities which minimize a value of an objective function based on a computed dose delivered to each voxel and the utility measure for that voxel summed over all voxels.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: April 25, 2023
    Assignees: University of Maryland, Baltimore, The Board of Regents of the University of Texas System, Broncus
    Inventors: Amit Sawant, Robert Timmerman, Yulong Yan, Henky Wibowo, Esther Vicente, Arezoo Modiri
  • SYSTEM AND METHOD FOR RADIATION THERAPY USING SPATIAL-FUNCTIONAL MAPPING AND DOSE SENSITIVITY OF BRANCHING STRUCTURES AND FUNCTIONAL SUB-VOLUMES
    Publication number: 20200330795
    Abstract: A method and apparatus for radiation therapy using functional measurements of branching structures. The method includes determining a location of each voxel of a plurality of voxels in a reference frame of a radiation device. The method further includes obtaining measurements that indicate a tissue type at each voxel. The method further includes determining a subset of the voxels based on an anatomical parameter of a respective branching structure of a set of branching structures indicated by the measurements. The method further includes determining a subset of the voxels that enclose an organ-at-risk (OAR) volume. The method further includes determining a value of a utility measure at each voxel. The method further includes determining a series of beam shapes and intensities which minimize a value of an objective function based on a computed dose delivered to each voxel and the utility measure for that voxel summed over all voxels.
    Type: Application
    Filed: April 20, 2020
    Publication date: October 22, 2020
    Inventors: Amit Sawant, Robert Timmerman, Yulong Yan, Henky Wibowo, Esther Vicente, Arezoo Modiri