Patents by Inventor Ari D. Brooks
Ari D. Brooks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200141940Abstract: One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.Type: ApplicationFiled: December 2, 2019Publication date: May 7, 2020Applicant: Drexel UniversityInventors: Wei-Heng Shih, Wan Y. Shih, Giang Au, Ari D. Brooks, Vanlila K. Swami
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Patent number: 10527625Abstract: One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.Type: GrantFiled: July 6, 2016Date of Patent: January 7, 2020Assignee: Drexel UniversityInventors: Wei-Heng Shih, Wan Y. Shih, Giang Au, Ari D. Brooks, Vanlila K. Swami
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Patent number: 10076247Abstract: A sensor system for measuring an elastic modulus and a shear modulus and a method for evaluating a tissue. The invention pertains to a method for determining the presence of and/or characterizing abnormal growths, using a piezoelectric finger sensor (PEFS) system. The PEFS system may be particularly useful for screening for tumors and various forms of cancer. Additionally, the PEFS system may be useful for various dermatological applications.Type: GrantFiled: August 21, 2014Date of Patent: September 18, 2018Inventors: Wan Y. Shih, Wei-Heng Shih, Hakki Yegingil, Ari D. Brooks
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Publication number: 20170212121Abstract: One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.Type: ApplicationFiled: July 6, 2016Publication date: July 27, 2017Applicant: Drexel UniversityInventors: Wei-Heng Shih, Wan Y. Shih, Giang Au, Ari D. Brooks, Vanlila K. Swami
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Publication number: 20170202218Abstract: Aspects of the present subject matter are directed to a method comprising contacting an fluid, optionally containing an added organic material, with a non-thermal plasma to form a disinfection composition, wherein the disinfection composition is a liquid, and contacting a surface with the disinfection composition, wherein the surface is at least partially disinfected upon contact with the disinfection composition. Additional aspects of the present subject matter are directed to a method comprising forming a disinfection composition by contacting an organic material with a non-thermal plasma, wherein the disinfection composition is a liquid. A further aspect of the present subject matter is directed to a disinfection composition comprising an organic material contacted by a non-thermal plasma, wherein the disinfection composition is a liquid.Type: ApplicationFiled: February 1, 2017Publication date: July 20, 2017Inventors: GREGORY FRIDMAN, SIN PARK, NATALIE SHAINSKY, DANIL V. DOBRYNIN, ALEXANDER RABINOVICH, GENNADY FRIEDMAN, ALEXANDER FRIDMAN, MOOGEGA COOPER, ARI D. BROOKS, SURESH G. JOSHI, ALEXANDER E. POOR, UTKU K. ERCAN, MARK INGERMAN
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Patent number: 9585390Abstract: Aspects of the present subject matter are directed to a method comprising contacting an fluid, optionally containing an added organic material, with a non-thermal plasma to form a disinfection composition, wherein the disinfection composition is a liquid, and contacting a surface with the disinfection composition, wherein the surface is at least partially disinfected upon contact with the disinfection composition. Additional aspects of the present subject matter are directed to a method comprising forming a disinfection composition by contacting an organic material with a non-thermal plasma, wherein the disinfection composition is a liquid. A further aspect of the present subject matter is directed to a disinfection composition comprising an organic material contacted by a non-thermal plasma, wherein the disinfection composition is a liquid.Type: GrantFiled: August 3, 2011Date of Patent: March 7, 2017Assignee: Drexel UniversityInventors: Gregory Fridman, Sin Park, Natalie Shainsky, Danil V. Dobrynin, Alexander Rabinovich, Gennady Friedman, Alexander Fridman, Moogega Cooper, Ari D. Brooks, Suresh G. Joshi, Alexander E. Poor, Utku K. Ercan, Mark Ingerman
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Patent number: 9417240Abstract: One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.Type: GrantFiled: May 25, 2012Date of Patent: August 16, 2016Assignee: Drexel UniversityInventors: Wei-Heng Shih, Wan Y. Shih, Giang Au, Ari D. Brooks, Vanlila K. Swami
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Publication number: 20150038584Abstract: Aspects of the present subject matter are directed to a method comprising contacting an fluid, optionally containing an added organic material, with a non-thermal plasma to form a disinfection composition, wherein the disinfection composition is a liquid, and contacting a surface with the disinfection composition, wherein the surface is at least partially disinfected upon contact with the disinfection composition. Additional aspects of the present subject matter are directed to a method comprising forming a disinfection composition by contacting an organic material with a non-thermal plasma, wherein the disinfection composition is a liquid. A further aspect of the present subject matter is directed to a disinfection composition comprising an organic material contacted by a non-thermal plasma, wherein the disinfection composition is a liquid.Type: ApplicationFiled: August 3, 2011Publication date: February 5, 2015Applicants: Philadelphia Health & Education Corporation d/b/a Drexel University College of Medicine, DREXEL UNIVERSITYInventors: Gregory Fridman, Sin Park, Natalie Shainsky, Danil V. Dobrynin, Alexander Rabinovich, Gennady Friedman, Alexander Fridman, Moogega Cooper, Ari D. Brooks, Suresh G. Joshi, Alexander E. Poor, Utku K. Ercan, Mark Ingerman
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Publication number: 20150025418Abstract: A sensor system for measuring an elastic modulus and a shear modulus and a method for evaluating a tissue. The invention pertains to a method for determining the presence of and/or characterizing abnormal growths, using a piezoelectric finger sensor (PEFS) system. The PEFS system may be particularly useful for screening for tumors and various forms of cancer. Additionally, the PEFS system may be useful for various dermatological applications.Type: ApplicationFiled: August 21, 2014Publication date: January 22, 2015Applicants: DREXEL UNIVERSITY, PHILADELPHIA HEALTH & EDUCATION CORPORATION d/b/a DREXEL UNIVERSITY COLLEGE OF MEDICINEInventors: Wan Y. SHIH, Wei-Heng SHIH, Hakki YEGINGIL, Ari D. BROOKS
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Patent number: 8845555Abstract: The present invention provides a sensor system for measuring an elastic modulus and a shear modulus and a method for using the sensor system to evaluate a tissue by determining the presence of and/or characterizing abnormal growths. The method involves applying a set of forces of different magnitudes to one or more locations of tissue, detecting the corresponding displacements due to said applied forces, determining the forces acting on those locations of tissue which are a combination of forces from the applied voltages and the countering forces from tissue deformation, obtaining the elastic modulus and/or shear modulus for a plurality of locations, and determining abnormal growth invasiveness, malignancy or the presence of a tumor from said elastic and/or shear moduli.Type: GrantFiled: September 19, 2013Date of Patent: September 30, 2014Assignees: Drexel University, Philadelphia Health & Education CorporationInventors: Wan Y. Shih, Wei-Heng Shih, Hakki Yegingil, Ari D. Brooks
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Publication number: 20140080141Abstract: One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.Type: ApplicationFiled: May 25, 2012Publication date: March 20, 2014Applicants: PHILADELPHIA HEALTH & EDUCATION CORPORATION, DREXEL UNIVERSITYInventors: Wei-Heng Shih, Wan Y. Shih, Giang Au, Ari D. Brooks, Vanlila K. Swami
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Publication number: 20140058260Abstract: The present invention provides a sensor system for measuring an elastic modulus and a shear modulus and a method for using the sensor system to evaluate a tissue by determining the presence of and/or characterizing abnormal growths. The method involves applying a set of forces of different magnitudes to one or more locations of tissue, detecting the corresponding displacements due to said applied forces, determining the forces acting on those locations of tissue which are a combination of forces from the applied voltages and the countering forces from tissue deformation, obtaining the elastic modulus and/or shear modulus for a plurality of locations, and determining abnormal growth invasiveness, malignancy or the presence of a tumor from said elastic and/or shear moduli.Type: ApplicationFiled: September 19, 2013Publication date: February 27, 2014Applicants: PHILADELPHIA HEALTH & EDUCATION CORPORATION d/b/a DREXEL UNIVERSITY COLLEGE OF M, DREXEL UNIVERSITYInventors: Wan Y. SHIH, Wei-Heng SHIH, Hakki YEGINGIL, Ari D. BROOKS
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Patent number: 8562546Abstract: The present invention provides a sensor system for measuring an elastic modulus and a shear modulus and a method for using the sensor system to evaluate a tissue by determining the presence of and/or characterizing abnormal growths. The method involves applying a set of forces of different magnitudes to one or more locations of tissue, detecting the corresponding displacements due to said applied forces, determining the forces acting on those locations of tissue which are a combination of forces from the applied voltages and the countering forces from tissue deformation, obtaining the elastic modulus and/or shear modulus for a plurality of locations, and determining abnormal growth invasiveness, malignancy or the presence of a tumor from said elastic and/or shear moduli.Type: GrantFiled: May 15, 2009Date of Patent: October 22, 2013Assignee: Drexel UniversityInventors: Wan Y. Shih, Wei-Heng Shih, Hakki Yegingil, Ari D. Brooks
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Publication number: 20110172565Abstract: A sensor system for measuring an elastic modulus and a shear modulus and a method for evaluating a tissue. The invention pertains to a method for determining the presence of and/or characterizing abnormal growths, using a piezoelectric finger sensor (PEFS) system. The PEFS system may be particularly useful for screening for tumors and various forms of cancer. Additionally, the PEFS system may be useful for various dermatological applications.Type: ApplicationFiled: May 15, 2009Publication date: July 14, 2011Applicant: DREXEL UNIVERSITYInventors: Wan Y. Shih, Wei-Heng Shih, Hakki Yegingil, Ari D. Brooks
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Publication number: 20100114129Abstract: The instant invention concerns a device for joining tissue comprising a ring and rivet, the ring comprises a biocompatible and biodegradable polymer and contains at least one bioactive agent. The rivet has a hollow lumen. The invention also relates to methods of making such devices and the use of such devices in joining tissue.Type: ApplicationFiled: July 17, 2007Publication date: May 6, 2010Inventors: Margaret A. Wheatley, Ari D. Brooks