Abstract: Ingestible radio frequency identification (RFID) tags are disclosed. A system embodiment includes, but is not limited to, an RFID tag including a flexible substrate foldable between a planar configuration and a tubular configuration, a conductive element disposed on the flexible substrate, and an RFID tag chip electrically coupled with the conductive element; a capsule structured and dimensioned for ingestion by a biological subject, the capsule including a shell structured and dimensioned to enclose a medication for the biological subject simultaneously with the RFID tag when the flexible substrate is in the tubular configuration, but not when the flexible substrate is in the planar configuration; and a pH switch structure coupled to an exterior surface of the capsule, the pH switch configured to deactivate the RFID tag in a first configuration and to permit activation of the RFID tag in a second configuration within the biological subject.

Abstract: The present disclosure relates to applicators for microneedle array patches and methods of application of microneedle array patches to a skin surface. The applicator can include a shaft having an opening at a first end for affixing a microneedle array patch, a plunger positioned substantially within the shaft, a loading mechanism operably associated with the plunger within the shaft, and a force applicator. The method can include affixing the microneedle array patch to a first end of a plunger of a microneedle array patch applicator, loading the plunger and the affixed microneedle array patch to a loaded position, positioning the opening against the skin region of the individual and operating the force applicator to release the plunger.

Abstract: Ingestible radio frequency identification (RFID) tags are disclosed. A system embodiment includes, but is not limited to, an RFID tag including a flexible substrate foldable between a planar configuration and a tubular configuration, a conductive element disposed on the flexible substrate, and an RFID tag chip electrically coupled with the conductive element; a capsule structured and dimensioned for ingestion by a biological subject, the capsule including a shell structured and dimensioned to enclose a medication for the biological subject simultaneously with the RFID tag when the flexible substrate is in the tubular configuration, but not when the flexible substrate is in the planar configuration; and a pH switch structure coupled to an exterior surface of the capsule, the pH switch configured to deactivate the RFID tag in a first configuration and to permit activation of the RFID tag in a second configuration within the biological subject.

Abstract: The present technology relates generally to fluidics devices for measuring platelet coagulation and associated systems and methods. In some embodiments, a fluidics device includes an array of microstructures including pairs of generally rigid blocks and generally flexible posts. The fluidics device further includes at least one fluid channel configured to accept the array. The fluidics device can further include a measuring element configured to measure a degree of deflection of one or more of the flexible posts in the array. In some embodiments, the fluidics device comprises a handheld device and usable for point of care testing of platelet forces and coagulation.